rs74535574
|
|
Colorectal Neoplasms
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
"APC mutations in sporadic colorectal tumors: A mutational ""hotspot"" and interdependence of the ""two hits""."
|
10737795 |
2000 |
rs121913332
|
|
Colorectal Neoplasms
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
"APC mutations in sporadic colorectal tumors: A mutational ""hotspot"" and interdependence of the ""two hits""."
|
10737795 |
2000 |
rs121913328
|
|
Colorectal Neoplasms
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
"APC mutations in sporadic colorectal tumors: A mutational ""hotspot"" and interdependence of the ""two hits""."
|
10737795 |
2000 |
rs121913327
|
|
Colorectal Neoplasms
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
"APC mutations in sporadic colorectal tumors: A mutational ""hotspot"" and interdependence of the ""two hits""."
|
10737795 |
2000 |
rs113488022
|
|
Colorectal Neoplasms
|
T |
0.790 |
CausalMutation
|
CLINVAR |
A genetic progression model of Braf(V600E)-induced intestinal tumorigenesis reveals targets for therapeutic intervention.
|
23845441 |
2013 |
rs121913332
|
|
Colorectal Neoplasms
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
A single-nucleotide substitution mutator phenotype revealed by exome sequencing of human colon adenomas.
|
23204322 |
2012 |
rs121913327
|
|
Colorectal Neoplasms
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
A single-nucleotide substitution mutator phenotype revealed by exome sequencing of human colon adenomas.
|
23204322 |
2012 |
rs121913328
|
|
Colorectal Neoplasms
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
A unique profile of adenomatous polyposis coli gene mutations in Iranian patients suffering sporadic colorectal cancer.
|
24518971 |
2014 |
rs727502902
|
|
Colorectal Neoplasms
|
TGTA |
0.700 |
CausalMutation
|
CLINVAR |
Alterations of BRAF and HIPK2 loci predominate in sporadic pilocytic astrocytoma.
|
19794125 |
2009 |
rs113488022
|
|
Colorectal Neoplasms
|
T |
0.790 |
CausalMutation
|
CLINVAR |
Antitumor activity of BRAF inhibitor vemurafenib in preclinical models of BRAF-mutant colorectal cancer.
|
22180495 |
2012 |
rs121913361
|
|
Colorectal Neoplasms
|
G |
0.700 |
CausalMutation
|
CLINVAR |
Antitumor activity of BRAF inhibitor vemurafenib in preclinical models of BRAF-mutant colorectal cancer.
|
22180495 |
2012 |
rs104894229
|
|
Colorectal Neoplasms
|
G |
0.700 |
GeneticVariation
|
CLINVAR |
APC inhibits ERK pathway activation and cellular proliferation induced by RAS.
|
16478791 |
2006 |
rs74535574
|
|
Colorectal Neoplasms
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
APC mutations occur early during colorectal tumorigenesis.
|
1528264 |
1992 |
rs121913462
|
|
Colorectal Neoplasms
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
APC mutations occur early during colorectal tumorigenesis.
|
1528264 |
1992 |
rs121913333
|
|
Colorectal Neoplasms
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
APC mutations occur early during colorectal tumorigenesis.
|
1528264 |
1992 |
rs121913332
|
|
Colorectal Neoplasms
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
APC mutations occur early during colorectal tumorigenesis.
|
1528264 |
1992 |
rs121913328
|
|
Colorectal Neoplasms
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
APC mutations occur early during colorectal tumorigenesis.
|
1528264 |
1992 |
rs121913327
|
|
Colorectal Neoplasms
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
APC mutations occur early during colorectal tumorigenesis.
|
1528264 |
1992 |
rs121913326
|
|
Colorectal Neoplasms
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
APC mutations occur early during colorectal tumorigenesis.
|
1528264 |
1992 |
rs112445441
|
|
Colorectal Neoplasms
|
T |
0.700 |
CausalMutation
|
CLINVAR |
Association of KRAS G13D tumor mutations with outcome in patients with metastatic colorectal cancer treated with first-line chemotherapy with or without cetuximab.
|
22734028 |
2012 |
rs112445441
|
|
Colorectal Neoplasms
|
T |
0.700 |
CausalMutation
|
CLINVAR |
Association of KRAS p.G13D mutation with outcome in patients with chemotherapy-refractory metastatic colorectal cancer treated with cetuximab.
|
20978259 |
2010 |
rs121913250
|
|
Colorectal Neoplasms
|
T |
0.700 |
CausalMutation
|
CLINVAR |
AZD6244 (ARRY-142886), a potent inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1/2 kinases: mechanism of action in vivo, pharmacokinetic/pharmacodynamic relationship, and potential for combination in preclinical models.
|
17699718 |
2007 |
rs121913250
|
|
Colorectal Neoplasms
|
A |
0.700 |
CausalMutation
|
CLINVAR |
AZD6244 (ARRY-142886), a potent inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1/2 kinases: mechanism of action in vivo, pharmacokinetic/pharmacodynamic relationship, and potential for combination in preclinical models.
|
17699718 |
2007 |
rs121913237
|
|
Colorectal Neoplasms
|
A |
0.700 |
CausalMutation
|
CLINVAR |
AZD6244 (ARRY-142886), a potent inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1/2 kinases: mechanism of action in vivo, pharmacokinetic/pharmacodynamic relationship, and potential for combination in preclinical models.
|
17699718 |
2007 |
rs121913237
|
|
Colorectal Neoplasms
|
T |
0.700 |
CausalMutation
|
CLINVAR |
AZD6244 (ARRY-142886), a potent inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1/2 kinases: mechanism of action in vivo, pharmacokinetic/pharmacodynamic relationship, and potential for combination in preclinical models.
|
17699718 |
2007 |