Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10012
rs10012
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.020 GeneticVariation BEFREE Haplotypes of rs1056827 and rs10012 or rs1056827 and rs1056836 revealed an association with colorectal cancer which was significantly stronger in the homozygous carriers. 20701755

2010

dbSNP: rs10012
rs10012
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.020 GeneticVariation BEFREE In summary, this meta-analysis indicates that CYP1A2*F, CYP1B1 Leu432Val, Asn453Ser, and Arg48Gly polymorphisms do not support an association with colorectal cancer, and further studies are needed to investigate the association. 25115775

2014

dbSNP: rs10036748
rs10036748
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.010 GeneticVariation BEFREE Additionally, SNPs in this study except rs7708392 and rs10036748 were found a modest connection with CRC risk. 28915643

2017

dbSNP: rs10046
rs10046
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.010 GeneticVariation BEFREE Two SNPs including rs2069521 and rs10046 in genes of cytochrome P450 (CYP) superfamily were found significantly associated with CRC risk. 25109722

2014

dbSNP: rs10049390
rs10049390
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
A 0.700 GeneticVariation GWASCAT Discovery of common and rare genetic risk variants for colorectal cancer. 30510241

2019

dbSNP: rs10090154
rs10090154
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.030 GeneticVariation BEFREE None of the other three single nucleotide polymorphisms, two associated with prostate (rs10090154 and rs7000448) and one with both prostate and colorectal cancers (rs6583267), was associated with breast cancer risk in our study. 18349290

2008

dbSNP: rs10090154
rs10090154
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.030 GeneticVariation BEFREE We found an increased risk of CRC with rs6983267 but not with rs10090154. 19857256

2009

dbSNP: rs10090154
rs10090154
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.030 GeneticVariation BEFREE Two correlated SNPs--rs10090154 and rs4242382--in Region 1 of chromosome 8q24, a prostate cancer susceptibility region, demonstrated statistically significant associations with colorectal cancer risk. 23935004

2014

dbSNP: rs1011970
rs1011970
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
T 0.700 GeneticVariation GWASCAT Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations. 27197191

2016

dbSNP: rs10152518
rs10152518
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
G 0.700 GeneticVariation GWASCAT Association analyses identify 31 new risk loci for colorectal cancer susceptibility. 31089142

2019

dbSNP: rs10165970
rs10165970
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.010 GeneticVariation BEFREE Study distribution by tumor was as follows: breast cancer (n=15), prostate cancer (n=3), pancreatic cancer (n=2), non-Hodgkin's lymphoma (n=2), glioma (n=1), chronic lymphocytic leukemia (n=1), colorectal cancer (n=1), non-small cell lung cancer (n=1) and ovarian cancer (n=1).We identified 10 single nucleotide polymorphisms (SNPs) significantly associated with cancer risk: NPAS2 rs10165970 (mixed and breast cancer shiftworkers), rs895520 (mixed), rs17024869 (breast) and rs7581886 (breast); CLOCK rs3749474 (breast) and rs11943456 (breast); RORA rs7164773 (breast and breast cancer postmenopausal), rs10519097 (breast); RORB rs7867494 (breast cancer postmenopausal), PER3 rs1012477 (breast cancer subgroups) and assessed the level of quality evidence to be intermediate. 28177907

2017

dbSNP: rs10203853
rs10203853
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.010 GeneticVariation BEFREE UGT1A haplotype analysis found that the T-G haplotype in UGT1A10 exon 1 (block 2: rs17864678, rs10929251) decreased cancer risk for the colon [proximal (OR = 0.28, 95% CI = 0.11–0.69) and for the distal colon (OR = 0.32, 95% CI = 0.12–0.91)], and that the C-T-G haplotype in the 3′ region flanking the UGT1A shared exons (block 11: rs7578153, rs10203853, rs6728940) increased CRC risk in males (OR = 2.56, 95% CI = 1.10–5.95). 24822274

2014

dbSNP: rs10204525
rs10204525
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.010 GeneticVariation BEFREE Among the 14 SNPs, CCL2 rs4586 and PDCD1 rs10204525 were found to have an influence on the survival outcomes of the patients with resectable CRC. 27339628

2016

dbSNP: rs10211
rs10211
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.010 GeneticVariation BEFREE In the Czech population, carriers of the ancestral alleles of AGT rs699 and CYP3A7 rs10211 showed an increased risk of CRC (OR 1.26 and 1.38, respectively; two-sided p≤0.05), whereas carriers of the ancestral allele of ENPP1 rs1044498 had a decreased risk (OR 0.79; p≤0.05). 23036011

2012

dbSNP: rs1021737
rs1021737
CTH
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.010 GeneticVariation BEFREE In subsequent univariate analyses, participants with variant rs1021737 genotype had a decreased risk of KRAS-mutated CRC (OR per allele = 0.72, 95% CI = 0.50, 1.05), and an increased risk of BRAF-mutated CRC (OR per allele = 1.56, 95% CI = 1.07, 2.30), with weak evidence for heterogeneity (Pheterogeneity = 0.01). 29694444

2018

dbSNP: rs1023890
rs1023890
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
A 0.700 GeneticVariation GWASDB A colorectal cancer susceptibility new variant at 4q26 in the Spanish population identified by genome-wide association analysis. 24978480

2014

dbSNP: rs1028166
rs1028166
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
G 0.700 GeneticVariation GWASCAT No evidence of gene-calcium interactions from genome-wide analysis of colorectal cancer risk. 25192705

2014

dbSNP: rs1031245702
rs1031245702
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.010 GeneticVariation BEFREE Using a family-based study, we investigated the role of polymorphisms in 4 BER genes (APEX1 Gln51His, Asp148Glu; OGG1 Ser236Cys; PARP Val742Ala; and XRCC1 Arg194Trp, Arg280His, Arg399Gln) as potential CRC risk factors and modifiers of the association between diets high in red meat or poultry and CRC risk. 21037106

2010

dbSNP: rs10318
rs10318
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.730 GeneticVariation BEFREE At 15q13.3, rs10318 was associated with CRC in both populations. 20659471

2010

dbSNP: rs10318
rs10318
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.730 GeneticVariation BEFREE This meta-analysis demonstrated that the rs4779584 and rs10318 polymorphism at 15q13.3 is a risk factor associated with increased CRC/CRA susceptibility, but these associations vary in different ethnic populations. 25475391

2015

dbSNP: rs10318
rs10318
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.730 GeneticVariation BEFREE In two of the five genes originally associated with CRC, we found evidence for association in AAs including rs1862748 in CDH1 (OR(Add) = 0.82, P = 0.02) and in GREM1 the SNPs rs10318 (OR(Rec) = 60.1, P = 0.01), rs11632715 (OR(Rec) = 2.36; P = 0.004) and rs12902616 (OR(Rec) = 1.28, P = 0.005), the latter which is in linkage disequilibrium with the previously identified SNP rs4779584. 24753543

2014

dbSNP: rs10318
rs10318
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.730 GeneticVariation GWASDB Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer. 19011631

2008

dbSNP: rs1035209
rs1035209
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
T 0.810 GeneticVariation GWASDB We conducted replication of top ranked single nucleotide polymorphisms (SNPs) in additional series totalling 14 037 cases and 15 937 controls, identifying a new CRC risk locus at 10q24.2 [rs1035209; odds ratio (OR) = 1.13, P = 4.54 × 10(-11)]. 24737748

2014

dbSNP: rs1035209
rs1035209
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.810 GeneticVariation BEFREE We conducted replication of top ranked single nucleotide polymorphisms (SNPs) in additional series totalling 14 037 cases and 15 937 controls, identifying a new CRC risk locus at 10q24.2 [rs1035209; odds ratio (OR) = 1.13, P = 4.54 × 10(-11)]. 24737748

2014

dbSNP: rs1035209
rs1035209
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
T 0.810 GeneticVariation GWASCAT We conducted replication of top ranked single nucleotide polymorphisms (SNPs) in additional series totalling 14 037 cases and 15 937 controls, identifying a new CRC risk locus at 10q24.2 [rs1035209; odds ratio (OR) = 1.13, P = 4.54 × 10(-11)]. 24737748

2014