|
rs11571833
|
|
Squamous cell carcinoma
|
|
0.720 |
GeneticVariation
|
BEFREE |
Association of BRCA2 K3326* With Small Cell Lung Cancer and Squamous Cell Cancer of the Skin.
|
29767749 |
2018 |
|
rs11571833
|
|
Squamous cell carcinoma
|
|
0.720 |
GeneticVariation
|
BEFREE |
We analyzed the association between BRCA2 SNP rs11571833 and upper aerodigestive tract (UADT) cancer risk with multivariable unconditional logistic regression adjusted by sex and combinations of study and country for 5942 UADT squamous cell carcinoma case patients and 8086 control patients from nine different studies.All statistical tests were two-sided. rs11571833 was associated with UADT cancers (odds ratio = 2.53, 95% confidence interval = 1.89 to 3.38, P = 3x10(-10)) and was present in European, Latin American, and Indian populations but extremely rare in Japanese populations.
|
25838448 |
2015 |
|
rs1126809
|
|
Squamous cell carcinoma
|
|
0.710 |
GeneticVariation
|
BEFREE |
The TYR haplotype carrying only the Arg402Gln variant allele was significantly associated with SCC risk (OR, 1.35; 95% CI, 1.04-1.74).
|
19384953 |
2009 |
|
rs12203592
|
|
Squamous cell carcinoma
|
|
0.710 |
GeneticVariation
|
BEFREE |
Along with two known pigmentation loci, MC1R and OCA2, the IRF4 rs12203592 T allele was associated with an increased risk of each type of skin cancer (P value, 6.6 × 10(-4) for melanoma, 7.0 × 10(-7) for SCC, and 0.04 for BCC).
|
21270109 |
2011 |
|
rs12296850
|
|
Squamous cell carcinoma
|
|
0.710 |
GeneticVariation
|
BEFREE |
We found that rs12296850 in SLC17A8-NR1H4 gene region at12q23.1 was significantly associated with risk of lung SqCC at genome-wide significance level [additive model: odds ratio (OR) = 0.78, 95% confidence interval (CI) = 0.72-0.84, P = 1.19×10(-10)].
|
23341777 |
2013 |
|
rs16891982
|
|
Squamous cell carcinoma
|
|
0.710 |
GeneticVariation
|
BEFREE |
A melanoma- and pigmentation-associated variant in the SLC45A2 gene, L374F, is associated with risk of both BCC and squamous cell carcinoma.
|
19578363 |
2009 |
|
rs1800407
|
|
Squamous cell carcinoma
|
|
0.710 |
GeneticVariation
|
BEFREE |
The TYR haplotype carrying only the Arg402Gln variant allele was significantly associated with SCC risk (OR, 1.35; 95% CI, 1.04-1.74).
|
19384953 |
2009 |
|
rs1042522
|
|
Squamous cell carcinoma
|
|
0.090 |
GeneticVariation
|
BEFREE |
Effect of TP53 rs1042522 on the susceptibility of patients to oral squamous cell carcinoma and oral leukoplakia: a meta-analysis.
|
30126398 |
2018 |
|
rs1042522
|
|
Squamous cell carcinoma
|
|
0.090 |
GeneticVariation
|
BEFREE |
In this study, we analyzed the association of TP53 Pro72Arg polymorphism with squamous cell carcinoma of oral tongue (SCCOT) and esophagus (ESCC) in India.
|
25436609 |
2014 |
|
rs1042522
|
|
Squamous cell carcinoma
|
|
0.090 |
GeneticVariation
|
BEFREE |
Polymorphism Arg72Pro of p53 confers susceptibility to squamous cell carcinoma of lungs in a North Indian population.
|
23317414 |
2013 |
|
rs1042522
|
|
Squamous cell carcinoma
|
|
0.090 |
GeneticVariation
|
BEFREE |
P53 (Pro72Arg) polymorphism associated with the risk of oral squamous cell carcinoma in gutka, niswar and manpuri addicted patients of Pakistan.
|
23683469 |
2013 |
|
rs1042522
|
|
Squamous cell carcinoma
|
|
0.090 |
GeneticVariation
|
BEFREE |
In a large prospective cohort, p53 Arg72Pro Pro/Pro was associated with a 2-fold increased risk of death in all esophageal cancers, whereas MDM2 T309G G/G was associated with a 7-fold increased risk of death in squamous cell carcinoma.
|
19383811 |
2009 |
|
rs1042522
|
|
Squamous cell carcinoma
|
|
0.090 |
GeneticVariation
|
BEFREE |
We evaluated the effect of MDM2 SNP309 and its interaction with the p53 Arg72Pro polymorphism on pigmentary phenotypes and skin cancer risk in a nested case-control study within the Nurses' Health Study (NHS) among 219 melanoma cases, 286 squamous cell carcinoma (SCC) cases, 300 basal cell carcinoma (BCC) cases, and 873 controls, and among controls from other studies.
|
18814047 |
2009 |
|
rs1042522
|
|
Squamous cell carcinoma
|
|
0.090 |
GeneticVariation
|
BEFREE |
Our data indicate that the TP53 Arg72Pro polymorphism increases the risk for squamous-cell carcinoma mainly in heavy smokers.
|
17059853 |
2007 |
|
rs1042522
|
|
Squamous cell carcinoma
|
|
0.090 |
GeneticVariation
|
BEFREE |
We evaluated the association of the Arg72Pro polymorphism with skin cancer risk among Caucasians in a nested case-control study within the Nurses' Health Study (NHS) (219 melanoma, 286 squamous cell carcinoma (SCC), and 300 basal cell carcinoma (BCC) and 874 controls).
|
16739124 |
2006 |
|
rs1042522
|
|
Squamous cell carcinoma
|
|
0.090 |
GeneticVariation
|
BEFREE |
p53 codon 72 ARG/PRO polymorphism is not related to HPV type or lesion grade in low- and high-grade squamous intra-epithelial lesions and invasive squamous carcinoma of the cervix.
|
10449610 |
1999 |
|
rs1131691014
|
|
Squamous cell carcinoma
|
|
0.080 |
GeneticVariation
|
BEFREE |
In this study, we analyzed the association of TP53 Pro72Arg polymorphism with squamous cell carcinoma of oral tongue (SCCOT) and esophagus (ESCC) in India.
|
25436609 |
2014 |
|
rs1131691014
|
|
Squamous cell carcinoma
|
|
0.080 |
GeneticVariation
|
BEFREE |
P53 (Pro72Arg) polymorphism associated with the risk of oral squamous cell carcinoma in gutka, niswar and manpuri addicted patients of Pakistan.
|
23683469 |
2013 |
|
rs1131691014
|
|
Squamous cell carcinoma
|
|
0.080 |
GeneticVariation
|
BEFREE |
Polymorphism Arg72Pro of p53 confers susceptibility to squamous cell carcinoma of lungs in a North Indian population.
|
23317414 |
2013 |
|
rs1131691014
|
|
Squamous cell carcinoma
|
|
0.080 |
GeneticVariation
|
BEFREE |
In a large prospective cohort, p53 Arg72Pro Pro/Pro was associated with a 2-fold increased risk of death in all esophageal cancers, whereas MDM2 T309G G/G was associated with a 7-fold increased risk of death in squamous cell carcinoma.
|
19383811 |
2009 |
|
rs1131691014
|
|
Squamous cell carcinoma
|
|
0.080 |
GeneticVariation
|
BEFREE |
We evaluated the effect of MDM2 SNP309 and its interaction with the p53 Arg72Pro polymorphism on pigmentary phenotypes and skin cancer risk in a nested case-control study within the Nurses' Health Study (NHS) among 219 melanoma cases, 286 squamous cell carcinoma (SCC) cases, 300 basal cell carcinoma (BCC) cases, and 873 controls, and among controls from other studies.
|
18814047 |
2009 |
|
rs1131691014
|
|
Squamous cell carcinoma
|
|
0.080 |
GeneticVariation
|
BEFREE |
Our data indicate that the TP53 Arg72Pro polymorphism increases the risk for squamous-cell carcinoma mainly in heavy smokers.
|
17059853 |
2007 |
|
rs1131691014
|
|
Squamous cell carcinoma
|
|
0.080 |
GeneticVariation
|
BEFREE |
We evaluated the association of the Arg72Pro polymorphism with skin cancer risk among Caucasians in a nested case-control study within the Nurses' Health Study (NHS) (219 melanoma, 286 squamous cell carcinoma (SCC), and 300 basal cell carcinoma (BCC) and 874 controls).
|
16739124 |
2006 |
|
rs1131691014
|
|
Squamous cell carcinoma
|
|
0.080 |
GeneticVariation
|
BEFREE |
p53 codon 72 ARG/PRO polymorphism is not related to HPV type or lesion grade in low- and high-grade squamous intra-epithelial lesions and invasive squamous carcinoma of the cervix.
|
10449610 |
1999 |
|
rs878854066
|
|
Squamous cell carcinoma
|
|
0.080 |
GeneticVariation
|
BEFREE |
In this study, we analyzed the association of TP53 Pro72Arg polymorphism with squamous cell carcinoma of oral tongue (SCCOT) and esophagus (ESCC) in India.
|
25436609 |
2014 |