Source: GWASCAT

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2066844
rs2066844
NOD2
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		1.000 GeneticVariation GWASCAT Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. 28067908

2017
dbSNP: rs2066845
rs2066845
NOD2
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		1.000 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007

2016
dbSNP: rs11209026
rs11209026
IL23R
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		G 0.900 GeneticVariation GWASCAT A genome-wide association study on a southern European population identifies a new Crohn's disease susceptibility locus at RBX1-EP300. 22936669

2013
dbSNP: rs11209026
rs11209026
IL23R
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		G 0.900 GeneticVariation GWASCAT A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci. 22412388

2012
dbSNP: rs11209026
rs11209026
IL23R
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.900 GeneticVariation GWASCAT One is SNP rs11209026 in exon 9 of IL23R for association with Crohn's disease, which is predicted to be probably damaging by PolyPhen2. 22293688

2012
dbSNP: rs11209026
rs11209026
IL23R
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		G 0.900 GeneticVariation GWASCAT Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. 21102463

2010
dbSNP: rs11209026
rs11209026
IL23R
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.900 GeneticVariation GWASCAT Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci. 17804789

2007
dbSNP: rs11209026
rs11209026
IL23R
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.900 GeneticVariation GWASCAT Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4. 17447842

2007
dbSNP: rs2241880
rs2241880
ATG16L1 ; SCARNA5
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		G 0.900 GeneticVariation GWASCAT A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci. 22412388

2012
dbSNP: rs2241880
rs2241880
ATG16L1 ; SCARNA5
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		G 0.900 GeneticVariation GWASCAT Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. 17435756

2007
dbSNP: rs2066847
rs2066847
NOD2
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		T 0.890 GeneticVariation GWASCAT Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. 23128233

2012
dbSNP: rs2066847
rs2066847
NOD2
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.890 GeneticVariation GWASCAT Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease. 20570966

2010
dbSNP: rs2066847
rs2066847
NOD2
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		C 0.890 GeneticVariation GWASCAT Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. 18587394

2008
dbSNP: rs2542151
rs2542151
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		G 0.880 GeneticVariation GWASCAT Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. 18587394

2008
dbSNP: rs2542151
rs2542151
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		G 0.880 GeneticVariation GWASCAT Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. 17554300

2007
dbSNP: rs2542151
rs2542151
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.880 GeneticVariation GWASCAT Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. 17554261

2007
dbSNP: rs7517847
rs7517847
IL23R ; C1orf141
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.880 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007

2016
dbSNP: rs7517847
rs7517847
IL23R ; C1orf141
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		A 0.880 GeneticVariation GWASCAT Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. 26192919

2015
dbSNP: rs7517847
rs7517847
IL23R ; C1orf141
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.880 GeneticVariation GWASCAT Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. 17435756

2007
dbSNP: rs744166
rs744166
STAT3
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		A 0.870 GeneticVariation GWASCAT Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. 18587394

2008
dbSNP: rs1004819
rs1004819
IL23R ; C1orf141
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.860 GeneticVariation GWASCAT Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci. 17804789

2007
dbSNP: rs2476601
rs2476601
PTPN22 ; AP4B1-AS1
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.860 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007

2016
dbSNP: rs2476601
rs2476601
PTPN22 ; AP4B1-AS1
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.860 GeneticVariation GWASCAT Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. 26192919

2015
dbSNP: rs2476601
rs2476601
PTPN22 ; AP4B1-AS1
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		G 0.860 GeneticVariation GWASCAT Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. 21102463

2010
dbSNP: rs2476601
rs2476601
PTPN22 ; AP4B1-AS1
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		G 0.860 GeneticVariation GWASCAT Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. 18587394

2008