rs759834365
|
|
Depressed mood
|
|
0.100 |
GeneticVariation
|
BEFREE |
The association between BDNF Val66Met and SI was modeled using logistic regression adjusted for age and sex, and in secondary analyses also for depression.
|
30329132 |
2020 |
rs759834365
|
|
Depressive disorder
|
|
0.100 |
GeneticVariation
|
BEFREE |
The association between BDNF Val66Met and SI was modeled using logistic regression adjusted for age and sex, and in secondary analyses also for depression.
|
30329132 |
2020 |
rs759834365
|
|
Depressive Symptoms
|
|
0.100 |
GeneticVariation
|
BEFREE |
Thus, we assessed whether the functional single nucleotide polymorphism (SNP) on the BDNF gene, Val66Met, moderated the relationship between depressive symptoms and perceived social support and unsupportive relationships, and whether these associations differed by gender.
|
31364951 |
2020 |
rs759834365
|
|
Impaired cognition
|
|
0.100 |
GeneticVariation
|
BEFREE |
Carriage of BDNF Val66Met has been associated with faster cognitive decline and greater hippocampal atrophy in cognitively normal elderly.
|
31771052 |
2020 |
rs759834365
|
|
Mental Depression
|
|
0.100 |
GeneticVariation
|
BEFREE |
The association between BDNF Val66Met and SI was modeled using logistic regression adjusted for age and sex, and in secondary analyses also for depression.
|
30329132 |
2020 |
rs759834365
|
|
Nonorganic psychosis
|
|
0.100 |
GeneticVariation
|
BEFREE |
The BDNF-Val66Met polymorphism may index susceptibility to expression of psychosis along a spectrum.
|
29785763 |
2019 |
rs759834365
|
|
Obsessive-Compulsive Disorder
|
|
0.100 |
GeneticVariation
|
BEFREE |
Findings from this meta-analytic investigation of published literature provide little support for the Val66Met variant of BDNF as a predictor of OCD.
|
31291217 |
2019 |
rs759834365
|
|
Psychotic Disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
Chronic methamphetamine interacts with BDNF Val66Met to remodel psychosis pathways in the mesocorticolimbic proteome.
|
31822818 |
2019 |
rs759834365
|
|
Impaired cognition
|
|
0.100 |
GeneticVariation
|
BEFREE |
The association between higher BDNF levels and cognitive impairment, mainly attention in smokers appears to be dependent on the BDNF Val66Met polymorphism.
|
30659208 |
2019 |
rs759834365
|
|
Anxiety
|
|
0.100 |
GeneticVariation
|
BEFREE |
The BDNF Val66Met gene polymorphism is associated with increased alexithymic and anticipatory anxiety in patients with panic disorder.
|
30269521 |
2019 |
rs759834365
|
|
Parkinson Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Our analyses suggested the G196A (Val66Met) polymorphism was significantly associated with cognitive impairment in PD, especially in Caucasian populations.
|
31365694 |
2019 |
rs759834365
|
|
Abnormal behavior
|
|
0.100 |
GeneticVariation
|
BEFREE |
In humans and knock-in mice with a loss of function BDNF SNP (Val66Met), the functionality of this circuit was altered, resulting in social behavioral changes in human and mice.
|
30992540 |
2019 |
rs759834365
|
|
Impaired cognition
|
|
0.100 |
GeneticVariation
|
BEFREE |
A total of 1,081 adults without dementia (375 healthy subjects and 706 individuals with mild cognitive impairment) were recruited from the Alzheimer's Disease Neuroimaging Initiative (ADNI) to test the influence of BDNF Val66Met polymorphism on cognitive impairment, brain structure atrophy, and change in the levels of CSF biomarkers.
|
30775992 |
2019 |
rs759834365
|
|
Bipolar Disorder
|
|
0.100 |
GeneticVariation
|
BEFREE |
Few genetic studies exploring the impact of Val66Met on cognition in BD.
|
30078664 |
2019 |
rs759834365
|
|
Depressed mood
|
|
0.100 |
GeneticVariation
|
BEFREE |
Fifty-two samples from the depressed patient group were genotyped for the Val66Met BDNF polymorphism.
|
29802070 |
2019 |
rs759834365
|
|
Depressed mood
|
|
0.100 |
GeneticVariation
|
BEFREE |
The BDNF Val66Met contributed to the severity of CSI even after adjusting to PTSD, depression and LEC.
|
30904785 |
2019 |
rs759834365
|
|
Depressive Symptoms
|
|
0.100 |
GeneticVariation
|
BEFREE |
The objective was to investigate if high cadence cycling altered non-motor cognition and depression symptoms in individuals with Parkinson's disease (PD) and whether exercise responses were influenced by brain-derived neurotrophic factor (BDNF) Val66Met polymorphism.
|
31197095 |
2019 |
rs759834365
|
|
Depressive disorder
|
|
0.100 |
GeneticVariation
|
BEFREE |
The Val66Met polymorphism did not appear to predict BDNF levels, depression incidence, or modify the relationship between dietary quality and BDNF.
|
29280414 |
2019 |
rs759834365
|
|
Parkinson Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Our meta-analysis implicates Val66Met BDNF polymorphism may be associated with Parkinson's disease cognitive impairment, further well-designed studies with larger populations are required to validate these results owing to the limited research.
|
31104169 |
2019 |
rs759834365
|
|
Major Depressive Disorder
|
|
0.100 |
GeneticVariation
|
BEFREE |
The relationship was investigated between brain-derived neurotrophic factor (BDNF) concentrations, a <i>BDNF</i> polymorphism (196G>A), and the response to selective serotonin reuptake inhibitors (SSRIs) among Chinese patients with major depressive disorder (MDD).
|
31308724 |
2019 |
rs759834365
|
|
Obsessive-Compulsive Disorder
|
|
0.100 |
GeneticVariation
|
BEFREE |
Regression analysis determined the extent to which psychiatric comorbidity, illness severity, OCD symptom dimensions, childhood trauma history, and the Val66Met (rs6265) polymorphism of the brainderived neurotrophic factor (BDNF) gene predict lifetime suicidal ideation and attempts in adults with OCD.
|
31046037 |
2019 |
rs759834365
|
|
Impaired cognition
|
|
0.100 |
GeneticVariation
|
BEFREE |
Replication and Meta-analysis of the Association between BDNF Val66Met Polymorphism and Cognitive Impairment in Patients Receiving Chemotherapy.
|
30382534 |
2019 |
rs759834365
|
|
Impaired cognition
|
|
0.100 |
GeneticVariation
|
BEFREE |
Our meta-analysis implicates Val66Met BDNF polymorphism may be associated with Parkinson's disease cognitive impairment, further well-designed studies with larger populations are required to validate these results owing to the limited research.
|
31104169 |
2019 |
rs759834365
|
|
Psychotic Disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
The BDNF-Val66Met polymorphism may index susceptibility to expression of psychosis along a spectrum.
|
29785763 |
2019 |
rs759834365
|
|
Impaired cognition
|
|
0.100 |
GeneticVariation
|
BEFREE |
We examined whether BDNF Val66Met variation was associated with cognitive impairment in mTLE.
|
29952080 |
2019 |