Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs759834365
rs759834365
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.100 GeneticVariation BEFREE The BDNF Val66Met polymorphism was not independently associated with PSA during either the acute or chronic phase after stroke, but there was a significant interactive effect between BDNF methylation and genotype on PSA at 2 weeks. 31368178

2019

dbSNP: rs759834365
rs759834365
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.100 GeneticVariation BEFREE The effects of age on val66met associated alteration</span>s in plasticity and potential </span>consequences in terms of stroke are also discussed. 30118755

2019

dbSNP: rs759834365
rs759834365
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.100 GeneticVariation BEFREE Conclusions Our results suggest that the Val66Met polymorphism does not predict long-term, functional mobility following stroke. 29480080

2018

dbSNP: rs759834365
rs759834365
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.100 GeneticVariation BEFREE BDNF Val66Met is a determinant of motor skill learning after stroke and could be important for prognostic models. tDCS does not modulate motor skill learning in our study and might be less effective than previously assumed. 28751226

2018

dbSNP: rs759834365
rs759834365
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.100 GeneticVariation BEFREE Sixteen dysphagic stroke patients that completed a single-blind randomized sham controlled trial of pharyngeal electrical stimulation (PES) within 6 weeks of their stroke (N=38), were genotyped for the BDNF SNP Val66Met (rs6265) from saliva samples. 28317287

2017

dbSNP: rs759834365
rs759834365
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.100 GeneticVariation BEFREE The Role of the BDNF Val66Met Polymorphism in Recovery of Aphasia After Stroke. 28818006

2017

dbSNP: rs759834365
rs759834365
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.100 GeneticVariation BEFREE For the first time in an Iranian population, it was demonstrated that BDNF G196A variant plays a major role in stroke occurrence and consequences. 27077983

2016

dbSNP: rs759834365
rs759834365
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.100 GeneticVariation BEFREE Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism is associated with functional and cognitive outcomes of stroke and plays a key role in preventing neuronal death. 27071687

2016

dbSNP: rs759834365
rs759834365
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.100 GeneticVariation BEFREE The brain-derived neurotrophic factor Val66Met polymorphism and degeneration of the corticospinal tract after stroke: a diffusion tensor imaging study. 26228236

2016

dbSNP: rs759834365
rs759834365
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.100 GeneticVariation BEFREE The current study examined whether the presence of the BDNF val(66)met polymorphism is associated with reduced motor system activation after stroke. 26381810

2016

dbSNP: rs759834365
rs759834365
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.100 GeneticVariation BEFREE The impact of the Val66Met polymorphism on motor learning post-stroke has not been explored. 26487176

2016

dbSNP: rs759834365
rs759834365
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.100 GeneticVariation BEFREE The aim of present study was to assess the role of BDNF -196 G≯A (val66met) and -270 C≯T on clinical parameters and functional outcome in patients with ischemic and hemorrhagic stroke. 24722042

2014

dbSNP: rs759834365
rs759834365
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.100 GeneticVariation BEFREE To investigate the impact of this common BDNF SNP on stroke recovery, we used a mouse model that contains the human BDNF Val66Met variant in both alleles (BDNF(M/M)). 24523540

2014

dbSNP: rs759834365
rs759834365
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.100 GeneticVariation BEFREE This study aimed to investigate whether BDNF gene promoter methylation status and val66met polymorphism were associated with depression ascertained at two weeks and one year after stroke. 23399480

2013

dbSNP: rs759834365
rs759834365
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.100 GeneticVariation BEFREE The AA genotype of the BDNF G196A was associated with a poor outcome of recovery 3 months after stroke onset (P=0.008) was a novel finding, independent of other known predictors of poor outcome (P=0.012). 24035862

2013

dbSNP: rs759834365
rs759834365
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.100 GeneticVariation BEFREE This study aimed to investigate whether BDNF val66met polymorphism and promoter methylation status were associated with outcomes at two weeks and one year after stroke. 23240009

2012

dbSNP: rs759834365
rs759834365
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.100 GeneticVariation BEFREE This study hypothesized that the ApoE ε4 polymorphism and the val(66) met polymorphism for brain-derived neurotrophic factor (BDNF) are each associated with poorer outcome after stroke. 22221491

2012

dbSNP: rs759834365
rs759834365
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.100 GeneticVariation BEFREE Genetic variant of BDNF (Val66Met) polymorphism attenuates stroke-induced angiogenic responses by enhancing anti-angiogenic mediator CD36 expression. 21228186

2011

dbSNP: rs759834365
rs759834365
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.100 GeneticVariation BEFREE The BDNF val66met polymorphism may modify the association between stroke and depression. 17222482

2008