|
rs397507444
|
|
Prostate carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Methylenetetrahydrofolate reductase (MTHFR) c.677C>T and c.1298A>C variants were known to be associated with prostate cancer (PCa) risk with conflicting results, because of MTHFR and nutrient status interaction in the prostate development.
|
27819322 |
2016 |
|
rs397507444
|
|
Prostate carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
The association between the MTHFR A1298C CC genotype and prostate cancer risk may vary within different populations.
|
26782572 |
2015 |
|
rs397507444
|
|
Prostate carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Genetic polymorphisms in MTHFR (C677T, A1298C), MTR (A2756G) and MTRR (A66G) genes associated with pathological characteristics of prostate cancer in the Ecuadorian population.
|
23459165 |
2013 |
|
rs397507444
|
|
Prostate carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
No evidence of an association of MTHFR A1298C polymorphism with prostate cancer was found.
|
22370724 |
2012 |
|
rs397507444
|
|
Prostate carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Relationship between three polymorphisms of methylenetetrahydrofolate reductase (MTHFR C677T, A1298C, and G1793A) gene and risk of prostate cancer: a case-control study.
|
20564317 |
2010 |
|
rs397507444
|
|
Prostate carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
As for the A1298C polymorphism, there was no difference in distribution between the prostate cancer and control groups.
|
20944139 |
2010 |
|
rs397507444
|
|
Prostate carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
In this study, it has been observed that C677T polymorphism of the MTHFR gene produces no statistically significant difference for T allele frequency and the genotype frequency in prostate cancer patients and male controls with benign prostate hyperplasia not having prostate cancer, whereas it has been observed that A1298C polymorphism produces a statistically significant difference for C allele frequency in prostate cancer patients and controls and that it also produces a statistically marginal significance for genotype frequencies.
|
19814618 |
2009 |
|
rs397507444
|
|
Prostate carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
No evidence of an association of MTHFR A1298C polymorphism with prostate cancer was found.
|
19223177 |
2009 |
|
rs397507444
|
|
Prostate carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Neither the MTHFR 677C-->T nor the MTHFR 1298A-->C polymorphism was statistically significantly associated with the risk of prostate cancer in univariate analysis by conditional logistic regression.
|
16374229 |
2006 |
|
rs397507444
|
|
Prostate carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
In this study we examined the C677T and A1298C polymorphisms of the MTHFR gene in specimens from 81 patients with prostate cancer and 42 controls selected from patients with benign prostatic hypertrophy (BPH).
|
15492840 |
2004 |
|
rs397507444
|
|
Prostate carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Among all study subjects, we observed no association between the C677T variant and prostate cancer but a slight positive association between the A1298C variant and risk of this disease [odds ratio (OR) 1.41, 95% confidence interval (CI) 0.96-2.06; P = 0.08].
|
15298954 |
2004 |