rs10069690
|
|
Breast Carcinoma
|
|
0.750 |
GeneticVariation
|
BEFREE |
The variants rs10069690 and rs2853676 were also described as risk factors for BC.
|
29332343 |
2019 |
rs10069690
|
|
Breast Carcinoma
|
T |
0.750 |
GeneticVariation
|
GWASCAT |
Association analysis identifies 65 new breast cancer risk loci.
|
29059683 |
2017 |
rs10069690
|
|
Breast Carcinoma
|
T |
0.750 |
GeneticVariation
|
GWASCAT |
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.
|
29058716 |
2017 |
rs10069690
|
|
Breast Carcinoma
|
|
0.750 |
GeneticVariation
|
BEFREE |
This meta-analysis suggested that TERT rs2736109, rs2853669, rs2736098, and rs10069690 polymorphisms were associated with increased risk of developing breast cancer.
|
27461695 |
2017 |
rs10069690
|
|
Breast Carcinoma
|
|
0.750 |
GeneticVariation
|
BEFREE |
Different genotypes of rs3803662 (TOX3)/ (TNRC9)) in the case group and the control group are statistically significant (P = 0.044), but the ones of rs10069690 (TERT), rs2046210 (6q25.1), rs2981582 (EGFR2), and rs889312 (MAP3K1) have no significant statistical differences with breast cancer (P = 0.772, 0.308, 0.376, 0.468).
|
26803517 |
2016 |
rs10069690
|
|
Breast Carcinoma
|
T |
0.750 |
GeneticVariation
|
GWASCAT |
Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer.
|
25751625 |
2015 |
rs10069690
|
|
Breast Carcinoma
|
T |
0.750 |
GeneticVariation
|
GWASCAT |
Large-scale genotyping identifies 41 new loci associated with breast cancer risk.
|
23535729 |
2013 |
rs10069690
|
|
Breast Carcinoma
|
|
0.750 |
GeneticVariation
|
BEFREE |
Several TL-related single nucleotide polymorphisms had modest association with breast cancer risk overall, including TEP1 rs93886 (OR 0.82, 95% CI 0.70,0.95); TERF2 rs3785074 (OR 1.13, 95% CI 1.03,1.24); TERT rs4246742 (OR 0.85, 95% CI 0.77,0.93); TERT rs10069690 (OR 1.13, 95% CI 1.03,1.24); TERT rs2242652 (OR 1.51, 95% CI 1.11,2.04); and TNKS rs6990300 (OR 0.89, 95% CI 0.81,0.97).
|
23629941 |
2013 |
rs10069690
|
|
Breast Carcinoma
|
T |
0.750 |
GeneticVariation
|
GWASCAT |
Genome-wide association studies identify four ER negative-specific breast cancer risk loci.
|
23535733 |
2013 |
rs10069690
|
|
Breast Carcinoma
|
|
0.750 |
GeneticVariation
|
BEFREE |
Seven SNPs were statistically significant (P ≤ 0.05) with the risk of overall breast cancer in the same direction as previously reported: rs10069690 (5p15/TERT), rs999737 (14q24/RAD51L1), rs13387042 (2q35/TNP1), rs1219648 (10q26/FGFR2), rs8170 (19p13/BABAM1), rs17817449 (16q12/FTO), and rs13329835 (16q23/DYL2).
|
23593120 |
2013 |
rs10069690
|
|
Breast Carcinoma
|
T |
0.750 |
GeneticVariation
|
GWASCAT |
We identified a common risk variant for ER-negative breast cancer at the TERT-CLPTM1L locus on chromosome 5p15 (rs10069690: per-allele odds ratio (OR) = 1.18 per allele, P = 1.0 × 10(-10)).
|
22037553 |
2011 |