rs397514495
|
|
LI-FRAUMENI SYNDROME 1
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
Frequency of mutations in individuals with breast cancer referred for BRCA1 and BRCA2 testing using next-generation sequencing with a 25-gene panel.
|
25186627 |
2015 |
rs397514495
|
|
LI-FRAUMENI SYNDROME 1
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
Clinical Application of Multigene Panels: Challenges of Next-Generation Counseling and Cancer Risk Management.
|
26484312 |
2015 |
rs397514495
|
|
LI-FRAUMENI SYNDROME 1
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
Frequent germline deleterious mutations in DNA repair genes in familial prostate cancer cases are associated with advanced disease.
|
24556621 |
2014 |
rs397514495
|
|
LI-FRAUMENI SYNDROME 1
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
Prevalence of germline TP53 mutations in a prospective series of unselected patients with adrenocortical carcinoma.
|
23175693 |
2013 |
rs397514495
|
|
LI-FRAUMENI SYNDROME 1
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
Dominant-negative features of mutant TP53 in germline carriers have limited impact on cancer outcomes.
|
21343334 |
2011 |
rs397514495
|
|
LI-FRAUMENI SYNDROME 1
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
Analysis of the DNA-binding activity of p53 mutants using functional protein microarrays and its relationship to transcriptional activation.
|
20128691 |
2010 |
rs397514495
|
|
LI-FRAUMENI SYNDROME 1
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
Radio-induced malignancies after breast cancer postoperative radiotherapy in patients with Li-Fraumeni syndrome.
|
21059199 |
2010 |
rs397514495
|
|
LI-FRAUMENI SYNDROME 1
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
DNA binding cooperativity of p53 modulates the decision between cell-cycle arrest and apoptosis.
|
20471942 |
2010 |
rs397514495
|
|
LI-FRAUMENI SYNDROME 1
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
Mutant p53 protein localized in the cytoplasm inhibits autophagy.
|
18818522 |
2008 |
rs397514495
|
|
LI-FRAUMENI SYNDROME 1
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
Transcriptional functionality of germ line p53 mutants influences cancer phenotype.
|
17606709 |
2007 |
rs397514495
|
|
LI-FRAUMENI SYNDROME 1
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database.
|
17311302 |
2007 |
rs397514495
|
|
LI-FRAUMENI SYNDROME 1
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
Functional protein microarrays for parallel characterisation of p53 mutants.
|
15221755 |
2004 |
rs397514495
|
|
LI-FRAUMENI SYNDROME 1
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
Screening for germ line TP53 mutations in breast cancer patients.
|
1591732 |
1992 |
rs397514495
|
|
LI-FRAUMENI SYNDROME 1
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
Germ-line mutations of the p53 tumor suppressor gene in patients with high risk for cancer inactivate the p53 protein.
|
1631137 |
1992 |