Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs80357474
rs80357474
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.800 GeneticVariation UNIPROT Recommendations for reporting of secondary findings in clinical exome and genome sequencing, 2016 update (ACMG SF v2.0): a policy statement of the American College of Medical Genetics and Genomics. 27854360

2017

dbSNP: rs80357474
rs80357474
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.800 GeneticVariation UNIPROT ACMG policy statement: updated recommendations regarding analysis and reporting of secondary findings in clinical genome-scale sequencing. 25356965

2015

dbSNP: rs80357474
rs80357474
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.800 GeneticVariation UNIPROT A practice guideline from the American College of Medical Genetics and Genomics and the National Society of Genetic Counselors: referral indications for cancer predisposition assessment. 25394175

2015

dbSNP: rs80357474
rs80357474
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.800 GeneticVariation UNIPROT American Society of Clinical Oncology Expert Statement: collection and use of a cancer family history for oncology providers. 24493721

2014

dbSNP: rs80357474
rs80357474
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.800 GeneticVariation UNIPROT Summaries for patients. Assessing the genetic risk for BRCA-related breast or ovarian cancer in women: recommendations from the U.S. Preventive Services Task Force. 24366402

2014

dbSNP: rs80357474
rs80357474
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.800 GeneticVariation UNIPROT Risk assessment, genetic counseling, and genetic testing for BRCA-related cancer in women: U.S. Preventive Services Task Force recommendation statement. 24366376

2014

dbSNP: rs80357474
rs80357474
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.800 GeneticVariation UNIPROT NSGC practice guideline: risk assessment and genetic counseling for hereditary breast and ovarian cancer. 23188549

2013

dbSNP: rs80357474
rs80357474
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.800 GeneticVariation UNIPROT ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing. 23788249

2013

dbSNP: rs80357474
rs80357474
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.800 GeneticVariation UNIPROT Tamoxifen and risk of contralateral breast cancer for BRCA1 and BRCA2 mutation carriers. 23918944

2013

dbSNP: rs80357474
rs80357474
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.800 GeneticVariation UNIPROT American Society of Clinical Oncology policy statement update: genetic and genomic testing for cancer susceptibility. 20065170

2010

dbSNP: rs80357474
rs80357474
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.800 GeneticVariation UNIPROT ACOG Practice Bulletin No. 103: Hereditary breast and ovarian cancer syndrome. 19305347

2009

dbSNP: rs80357474
rs80357474
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.800 GeneticVariation UNIPROT The emerging landscape of breast cancer susceptibility. 18163131

2008

dbSNP: rs80357474
rs80357474
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.800 GeneticVariation UNIPROT Risk assessment and genetic counseling for hereditary breast and ovarian cancer: recommendations of the National Society of Genetic Counselors. 17508274

2007

dbSNP: rs80357474
rs80357474
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.800 GeneticVariation UNIPROT American Cancer Society guidelines for breast screening with MRI as an adjunct to mammography. 17392385

2007

dbSNP: rs80357474
rs80357474
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.800 GeneticVariation UNIPROT Genetic cancer risk assessment and counseling: recommendations of the national society of genetic counselors. 15604628

2004

dbSNP: rs80357474
rs80357474
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
0.800 GeneticVariation UNIPROT American Society of Clinical Oncology policy statement update: genetic testing for cancer susceptibility. 12692171

2003

dbSNP: rs80357474
rs80357474
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
G 0.800 CausalMutation CLINVAR

dbSNP: rs1057517574
rs1057517574
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
T 0.700 GeneticVariation CLINVAR

dbSNP: rs1057517574
rs1057517574
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
T 0.700 CausalMutation CLINVAR

dbSNP: rs1057517590
rs1057517590
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
C 0.700 GeneticVariation CLINVAR

dbSNP: rs1057517637
rs1057517637
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
GC 0.700 GeneticVariation CLINVAR Detection of high frequency of mutations in a breast and/or ovarian cancer cohort: implications of embracing a multi-gene panel in molecular diagnosis in India. 26911350

2016

dbSNP: rs1057517637
rs1057517637
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
GC 0.700 GeneticVariation CLINVAR Functional assay for BRCA1: mutagenesis of the COOH-terminal region reveals critical residues for transcription activation. 10811118

2000

dbSNP: rs1057518636
rs1057518636
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
GA 0.700 CausalMutation CLINVAR

dbSNP: rs1057518639
rs1057518639
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
G 0.700 GeneticVariation CLINVAR

dbSNP: rs1057519558
rs1057519558
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
A 0.700 CausalMutation CLINVAR