DisGeNET - a database of gene-disease associations

Source: BEFREE

Disease: Colorectal Carcinoma ×

Variant: rs1042028 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs1042028

SULT1A1

CUI:	C0009402
Disease:	Colorectal Carcinoma

Colorectal Carcinoma

0.030

GeneticVariation

BEFREE

This meta-analysis demonstrates that there is no association between the SULT1A1 R213H polymorphism and CRC.

21695180

2011

dbSNP:

rs1042028

SULT1A1

CUI:	C0009402
Disease:	Colorectal Carcinoma

Colorectal Carcinoma

0.030

GeneticVariation

BEFREE

Of the 224 SNPs investigated, 20 potential candidates associated with CRC were identified, including IL6 -174G>C (g.22062318G>C), XRCC1 c.685 C>T (p.Arg194Trp), PPARGC1A g.92945042C>T (3'UTR 96516), GSTP1 c.342A>C (p.Ile105Val), GSTM1 c.573C>G (p.Lys173Asn), and SULT1A1 g.19934792G>A (p.Arg213His).

16395669

2006

dbSNP:

rs1042028

SULT1A1

CUI:	C0009402
Disease:	Colorectal Carcinoma

Colorectal Carcinoma

0.030

GeneticVariation

BEFREE

From this study, we conclude that the SULT1A1 R213H polymorphism is not linked with colorectal cancer in this elderly Australian population.

12165038

2002