rs1130409
|
|
Colorectal Carcinoma
|
|
0.090 |
GeneticVariation
|
BEFREE |
Using DNA isolated from blood taken from patients (<i>n</i> = 312) and a control group (<i>n</i> = 320) with CRC, we have analyzed the polymorphisms of selected DNA repair genes and we have demonstrated that genotypes 51Gln/His and 148Asp/Glu of APEX gene and 23Gly/Ala of XPA gene may increase the risk of colorectal cancer.
|
28386271 |
2017 |
rs1130409
|
|
Colorectal Carcinoma
|
|
0.090 |
GeneticVariation
|
BEFREE |
To evaluate the effects of OGG1 (Ser326Cys, 11657A/G, and Arg154His) and APE1 (Asp148Glu, and T-656G) polymorphisms on colorectal cancer (CRC) risk.
|
27022219 |
2016 |
rs1130409
|
|
Colorectal Carcinoma
|
|
0.090 |
GeneticVariation
|
BEFREE |
APE1 Asp148Glu is associated with increased CRC risk and smoking alters the association between XRCC1 Arg399Gln and CRC risk in the Chinese Han population.
|
25024628 |
2014 |
rs1130409
|
|
Colorectal Carcinoma
|
|
0.090 |
GeneticVariation
|
BEFREE |
This meta-analysis suggested that the APE1 Asp148Glu polymorphism was not associated with colorectal cancer susceptibility among Asians or Caucasians.
|
24254302 |
2014 |
rs1130409
|
|
Colorectal Carcinoma
|
|
0.090 |
GeneticVariation
|
BEFREE |
Effect of APE1 T2197G (Asp148Glu) polymorphism on APE1, XRCC1, PARP1 and OGG1 expression in patients with colorectal cancer.
|
25268610 |
2014 |
rs1130409
|
|
Colorectal Carcinoma
|
|
0.090 |
GeneticVariation
|
BEFREE |
In conclusion, APE1 (Asp148Glu), PARP1 (Ala762Val), and XRCC1 (Arg399Gln, Arg194Trp) were associated with the susceptibility to CRC, but were not associated with the prognosis of CRC.
|
23430444 |
2013 |
rs1130409
|
|
Colorectal Carcinoma
|
|
0.090 |
GeneticVariation
|
BEFREE |
APE1 Asp148Glu and hOGG1 Ser326Cys polymorphisms might be associated with increasing risk of CRC in a Turkish population.
|
21561390 |
2011 |
rs1130409
|
|
Colorectal Carcinoma
|
|
0.090 |
GeneticVariation
|
BEFREE |
Using a family-based study, we investigated the role of polymorphisms in 4 BER genes (APEX1 Gln51His, Asp148Glu; OGG1 Ser236Cys; PARP Val742Ala; and XRCC1 Arg194Trp, Arg280His, Arg399Gln) as potential CRC risk factors and modifiers of the association between diets high in red meat or poultry and CRC risk.
|
21037106 |
2010 |
rs1130409
|
|
Colorectal Carcinoma
|
|
0.090 |
GeneticVariation
|
BEFREE |
The MUTYH Gln324His is strongly associated with colorectal cancer</span> susceptibility in never smoking history, whereas the APEX1 Asp148Glu genotype constitutes an increased risk of colorectal cancer when accompanied by smoking exposure.
|
18823566 |
2008 |