Variant Gene Disease Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1801131
rs1801131
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.060 GeneticVariation BEFREE In this hospital-based case-control study, the role of MTHFR C677T (rs1801133) and A1298C (rs1801131) genotypes in determining CRC risk were investigated among 362 patients with CRC and an equal number of age- and gender-matched healthy individuals. 29599316

2018

dbSNP: rs1801131
rs1801131
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.060 GeneticVariation BEFREE We genotyped MTHFR polymorphisms C677T (rs1801133) and A1298C (rs1801131) for 498 CRC patients treated with 5-FU-based chemotherapy after receiving surgery. 28044213

2017

dbSNP: rs1801131
rs1801131
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.060 GeneticVariation BEFREE The present meta-analysis showed that rs1801133 and rs1801131 might be CRC susceptibility variants in Americans and Australians and rs1801133 in Brazilians and Japanese. 25823789

2016

dbSNP: rs1801131
rs1801131
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.060 GeneticVariation BEFREE MTHFR Glu429Ala and ERCC5 His46His polymorphisms are associated with prognosis in colorectal cancer patients: analysis of two independent cohorts from Newfoundland. 23626689

2013

dbSNP: rs1801131
rs1801131
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.060 GeneticVariation BEFREE In the present study, we have assessed the association of six polymorphisms and relative haplotypes in the MTHFR gene (rs1801133 and rs1801131) and in the MTRR gene (rs1801394, rs1532268, rs162036, and rs10380) with the risk for colorectal cancer in 666 patients and 1377 controls from the Czech Republic. 21211571

2011

dbSNP: rs1801131
rs1801131
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.060 GeneticVariation BEFREE From studying the population-based families, the C677T (rs1801133) and A1298C (rs1801131) polymorphisms were associated with a decreased colorectal cancer risk overall [odds ratio (OR), 0.81; 95% confidence interval (95% CI), 0.63-1.04; and OR, 0.82; 95% CI, 0.64-1.07, respectively]. 20056627

2010