Source: BEFREE

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1805087
rs1805087
MTR
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.050 GeneticVariation BEFREE This meta-analysis suggests that the MTR A2756G polymorphism is not associated with CRC/CRA susceptibility and that gene-environment interaction may exist. 23593229

2013
dbSNP: rs1805087
rs1805087
MTR
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.050 GeneticVariation BEFREE No significant association was found between MTHFR A1298C and MTR A2756G polymorphisms and the risk of CRC. 22719222

2012
dbSNP: rs1805087
rs1805087
MTR
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.050 GeneticVariation BEFREE The A2756G MTR polymorphism was not associated with the risk of developing CRC. 18996879

2008
dbSNP: rs1805087
rs1805087
MTR
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.050 GeneticVariation BEFREE We evaluated the relation between the polymorphisms 677C --> T of the methylenetetrahydrofolate reductase (MTHFR) and 2756A --> G of the methionine synthase (MTR) genes and risk of colorectal cancer. 15598777

2004
dbSNP: rs1805087
rs1805087
MTR
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.050 GeneticVariation BEFREE In this study, we examined the relationship of a polymorphism (2756A-->G, asp-->gly) in the gene (MTR) for methionine synthase, another important enzyme in the same folate/methionine/homocyst(e)ine metabolic pathway, with risk of colorectal cancer among 356 cases and 476 cancer-free controls. 10498402

1999