Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1042522
rs1042522
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.080 GeneticVariation BEFREE We conducted a case-control study to examine whether two polymorphisms (i.e., rs4938723 in the promoter of pri-miR-34b/c and TP53 Arg72Pro) were linked to the carcinogenesis of cervical cancer among Chinese Han women. 26619844

2016

dbSNP: rs1042522
rs1042522
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.080 GeneticVariation BEFREE So, as to find the association of p53Arg <sup>72</sup> Pro towards lung carcinogenesis and overall survival of North Indian lung cancer patients, single nucleotide polymorphic variant (rs1042522) was analyzed. 27614750

2016

dbSNP: rs1042522
rs1042522
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.080 GeneticVariation BEFREE It is evident from our study that Arg72Pro SNP of TP53 gene is connected with higher susceptibility to thyroid cancer especially in young age group, female gender, non-smokers and patients with elevated TSH levels, hence, implicated in thyroid carcinogenesis. 25835179

2015

dbSNP: rs1042522
rs1042522
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.080 GeneticVariation BEFREE Polymorphism of p53 gene codon72 arginine (Arg)/proline (Pro) (rs1042522) may influence the function of p53 protein and then affect the processing of carcinogenesis. 24326769

2014

dbSNP: rs1042522
rs1042522
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.080 GeneticVariation BEFREE Similar thus inconclusive results are observed in ovarian cancer, which may suggest that the rs1042522 does not influence ovarian carcinogenesis directly, but might be linked to another pathogenic alteration. 23192612

2013

dbSNP: rs1042522
rs1042522
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.080 GeneticVariation BEFREE In case-only analysis, the homozygous p73 G4C14-to-A4T14 variant of p73 genotype was associated with the presence of the p53 exon 4 Arg72Pro allele (OR = 1.30, 95% CI, 1.02-1.64), which is suggestive of a biological interaction between the two genes in carcinogenesis. 21976716

2012

dbSNP: rs1042522
rs1042522
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.080 GeneticVariation BEFREE These findings suggest that under at least some conditions, the modulation of apoptosis by the R72P polymorphism does not affect the process of carcinogenesis. 20587514

2010

dbSNP: rs1042522
rs1042522
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.080 GeneticVariation BEFREE In addition to TP53 gene mutations, a common polymorphism, Arg72Pro, has been involved in the carcinogenesis process. 18068527

2008