Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1471
Gene Symbol: CST3
CST3
P01034 cystatin C 370 0.436 0.808 3.9E-03 0.020 None 1.000 2 0 2017 2019
Entrez Id: 2696
Gene Symbol: GIPR
GIPR
P48546 gastric inhibitory polypeptide receptor G-protein coupled receptor 58 0.670 0.538 2.0E-29 0.020 None 1.000 2 0 2011 2017
Entrez Id: 6611
Gene Symbol: SMS
SMS
P52788 spermine synthase 263 0.491 0.846 0.97 0.020 None 1.000 2 0 1993 2018
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.020 None 1.000 2 1 2014 2015
Entrez Id: 811
Gene Symbol: CALR
CALR
P27797 calreticulin Calcium-binding protein 487 0.413 0.923 0.89 0.020 None 1.000 2 0 2018 2019
Entrez Id: 9365
Gene Symbol: KL
KL
Q9UEF7 klotho Enzyme 332 0.448 0.769 2.2E-04 0.020 None 1.000 2 0 2013 2019
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.020 None 1.000 2 0 2019 2020
Entrez Id: 5979
Gene Symbol: RET
RET
P07949 ret proto-oncogene Kinase 607 0.392 0.885 1.00 0.020 None 1.000 2 0 2010 2019
Entrez Id: 7421
Gene Symbol: VDR
VDR
P11473 vitamin D receptor Nuclear receptor 852 0.352 0.885 1.7E-05 0.020 None 1.000 2 0 2015 2019
Entrez Id: 183
Gene Symbol: AGT
AGT
P01019 angiotensinogen Enzyme modulator 765 0.367 0.923 5.0E-08 0.020 None 1.000 2 1 2011 2017
Entrez Id: 5443
Gene Symbol: POMC
POMC
P01189 proopiomelanocortin 873 0.356 0.846 1.2E-04 0.020 None 1.000 2 0 2019 2020
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.020 None 1.000 2 1 1999 2017
Entrez Id: 54845
Gene Symbol: ESRP1
ESRP1
Q6NXG1 epithelial splicing regulatory protein 1 Nucleic acid binding 56 0.628 0.500 1.00 0.020 None 1.000 2 0 2012 2013
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.020 None 1.000 2 0 1993 2014
Entrez Id: 408
Gene Symbol: ARRB1
ARRB1
P49407 arrestin beta 1 Enzyme modulator 92 0.588 0.846 0.99 0.020 None 1.000 2 0 2013 2015
Entrez Id: 26291
Gene Symbol: FGF21
FGF21
Q9NSA1 fibroblast growth factor 21 Signaling 236 0.485 0.769 2.9E-02 0.020 None 1.000 2 0 2017 2019
Entrez Id: 2668
Gene Symbol: GDNF
GDNF
P39905 glial cell derived neurotrophic factor Signaling 409 0.434 0.885 0.20 0.020 None 1.000 2 0 2014 2019
Entrez Id: 6751
Gene Symbol: SSTR1
SSTR1
P30872 somatostatin receptor 1 G-protein coupled receptor 71 0.606 0.615 0.75 0.020 None 1.000 2 0 2018 2019
Entrez Id: 5567
Gene Symbol: PRKACB
PRKACB
P22694 protein kinase cAMP-activated catalytic subunit beta Kinase 33 0.670 0.577 0.35 0.010 None 1.000 1 0 2014 2014
Entrez Id: 5894
Gene Symbol: RAF1
RAF1
P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 470 0.418 0.885 0.85 0.010 None 1.000 1 0 2015 2015
Entrez Id: 9993
Gene Symbol: DGCR2
DGCR2
P98153 DiGeorge syndrome critical region gene 2 77 0.623 0.731 5.2E-06 0.010 None 1.000 1 0 2018 2018
Entrez Id: 581
Gene Symbol: BAX
BAX
Q07812 BCL2 associated X, apoptosis regulator Signaling 420 0.417 0.885 0.32 0.010 None 1.000 1 0 2005 2005
Entrez Id: 55890
Gene Symbol: GPRC5C
GPRC5C
Q9NQ84 G protein-coupled receptor class C group 5 member C G-protein coupled receptor 37 0.674 0.538 4.7E-04 0.010 None 1.000 1 0 2018 2018
Entrez Id: 56654
Gene Symbol: NPDC1
NPDC1
Q9NQX5 neural proliferation, differentiation and control 1 25 0.711 0.423 3.0E-02 0.010 None 1.000 1 0 2018 2018
Entrez Id: 55226
Gene Symbol: NAT10
NAT10
Q9H0A0 N-acetyltransferase 10 133 0.536 0.769 4.1E-22 0.010 None 1.000 1 0 2018 2018