Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 351
Gene Symbol: APP
APP
P05067 amyloid beta precursor protein enzyme modulator 371 0.430 0.862 6.2E-02 0.900 0.967 1764 39 1987 2018
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 770 0.352 0.931 1.7E-03 0.700 0.922 2356 11 1991 2018
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1
P49768 presenilin 1 calcium-binding protein; hydrolase; protease; signaling molecule 268 0.490 0.690 0.98 0.700 0.939 535 40 1990 2018
Entrez Id: 6653
Gene Symbol: SORL1
SORL1
Q92673 sortilin related receptor 1 receptor; transporter 69 0.619 0.483 1.1E-09 0.700 0.986 79 12 2004 2018
Entrez Id: 627
Gene Symbol: BDNF
BDNF
P23560 brain derived neurotrophic factor signaling molecule 591 0.382 0.828 0.70 0.600 0.976 126 7 1992 2018
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme hydrolase; protease 624 0.367 0.897 1.6E-37 0.600 0.859 71 4 1998 2018
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1035 0.312 0.931 0.13 0.600 0.946 60 0 1989 2017
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
P49841 glycogen synthase kinase 3 beta kinase; transferase 185 0.488 0.793 0.96 0.600 0.919 43 1 2000 2016
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2, apoptosis regulator signaling molecule 987 0.312 0.862 0.57 0.600 1.000 15 0 1996 2016
Entrez Id: 3643
Gene Symbol: INSR
INSR
P06213 insulin receptor 338 0.459 0.724 2.0E-05 0.590 1.000 11 0 2002 2016
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
P00749 plasminogen activator, urokinase hydrolase; protease 325 0.434 0.690 2.1E-06 0.580 1.000 18 1 1994 2014
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 498 0.400 0.793 0.39 0.580 1.000 10 0 2005 2018
Entrez Id: 3481
Gene Symbol: IGF2
IGF2
P01344 insulin like growth factor 2 505 0.399 0.828 4.7E-02 0.550 1.000 7 0 2002 2015
Entrez Id: 4852
Gene Symbol: NPY
NPY
P01303 neuropeptide Y signaling molecule 243 0.469 0.690 0.16 0.550 0.600 7 0 2000 2016
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
P08069 insulin like growth factor 1 receptor 373 0.433 0.828 0.99 0.520 1.000 5 0 2005 2013
Entrez Id: 3630
Gene Symbol: INS
INS
P01308 insulin 309 0.458 0.828 0.32 0.520 1.000 5 0 1991 2007
Entrez Id: 581
Gene Symbol: BAX
BAX
Q07812 BCL2 associated X, apoptosis regulator signaling molecule 267 0.450 0.862 0.30 0.510 1.000 5 0 1997 2011
Entrez Id: 5664
Gene Symbol: PSEN2
PSEN2
P49810 presenilin 2 hydrolase; protease; signaling molecule 108 0.567 0.517 2.4E-03 0.500 0.978 148 9 1995 2018
Entrez Id: 1191
Gene Symbol: CLU
CLU
P10909 clusterin 266 0.456 0.793 5.7E-05 0.500 0.963 85 6 1991 2018
Entrez Id: 54209
Gene Symbol: TREM2
TREM2
Q9NZC2 triggering receptor expressed on myeloid cells 2 178 0.572 0.552 4.0E-09 0.500 0.963 82 3 2007 2018
Entrez Id: 8301
Gene Symbol: PICALM
PICALM
Q13492 phosphatidylinositol binding clathrin assembly protein membrane traffic protein 36 0.639 0.310 1.00 0.500 0.957 50 16 2009 2018
Entrez Id: 10347
Gene Symbol: ABCA7
ABCA7
Q8IZY2 ATP binding cassette subfamily A member 7 transporter 46 0.690 0.379 4.5E-55 0.500 1.000 36 8 2011 2018
Entrez Id: 23607
Gene Symbol: CD2AP
CD2AP
Q9Y5K6 CD2 associated protein signaling molecule 52 0.642 0.448 0.29 0.500 1.000 13 2 2011 2018
Entrez Id: 1378
Gene Symbol: CR1
CR1
P17927 complement C3b/C4b receptor 1 (Knops blood group) 51 0.607 0.621 1.1E-33 0.460 1.000 11 8 2009 2018
Entrez Id: 7447
Gene Symbol: VSNL1
VSNL1
P62760 visinin like 1 40 0.652 0.345 0.49 0.450 1.000 6 3 2002 2016