Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor signaling molecule 1640 0.263 0.966 0.80 0.700 0.951 531 3 1989 2018
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Q9Y2R2 protein tyrosine phosphatase, non-receptor type 22 210 0.497 0.793 3.6E-19 0.700 0.905 141 5 2004 2018
Entrez Id: 1401
Gene Symbol: CRP
CRP
P02741 C-reactive protein 470 0.399 0.862 3.7E-03 0.600 0.939 73 0 1989 2016
Entrez Id: 3572
Gene Symbol: IL6ST
IL6ST
P40189 interleukin 6 signal transducer defense/immunity protein; signaling molecule 140 0.522 0.759 1.00 0.560 1.000 8 0 2000 2014
Entrez Id: 23569
Gene Symbol: PADI4
PADI4
Q9UM07 peptidyl arginine deiminase 4 76 0.592 0.586 2.6E-16 0.500 0.877 87 10 2003 2018
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
Q14765 signal transducer and activator of transcription 4 nucleic acid binding; transcription factor 161 0.515 0.690 0.78 0.500 0.891 51 6 2000 2016
Entrez Id: 7185
Gene Symbol: TRAF1
TRAF1
Q13077 TNF receptor associated factor 1 signaling molecule 76 0.580 0.690 1.2E-02 0.500 0.903 35 3 2007 2016
Entrez Id: 940
Gene Symbol: CD28
CD28
P10747 CD28 molecule 187 0.488 0.793 0.37 0.500 1.000 32 2 1997 2016
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3
P21580 TNF alpha induced protein 3 hydrolase; nucleic acid binding; protease 104 0.538 0.621 1.00 0.500 1.000 32 6 2007 2017
Entrez Id: 3663
Gene Symbol: IRF5
IRF5
Q13568 interferon regulatory factor 5 nucleic acid binding; transcription factor 161 0.518 0.690 8.5E-03 0.500 0.870 29 4 2005 2016
Entrez Id: 958
Gene Symbol: CD40
CD40
P25942 CD40 molecule 323 0.433 0.862 0.86 0.500 0.909 25 5 2002 2016
Entrez Id: 3115
Gene Symbol: HLA-DPB1
HLA-DPB1
P04440 major histocompatibility complex, class II, DP beta 1 defense/immunity protein 215 0.484 0.862 4.3E-09 0.500 0.955 25 62 1988 2015
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
P01589 interleukin 2 receptor subunit alpha receptor 361 0.419 0.828 5.2E-02 0.500 1.000 24 2 1992 2016
Entrez Id: 1235
Gene Symbol: CCR6
CCR6
P51684 C-C motif chemokine receptor 6 148 0.522 0.724 6.2E-03 0.500 1.000 17 8 2001 2016
Entrez Id: 3570
Gene Symbol: IL6R
IL6R
P08887 interleukin 6 receptor defense/immunity protein; signaling molecule 165 0.496 0.724 2.8E-05 0.500 1.000 17 5 2001 2016
Entrez Id: 4261
Gene Symbol: CIITA
CIITA
P33076 class II major histocompatibility complex transactivator 105 0.564 0.724 1.0E-07 0.500 0.643 16 1 2005 2017
Entrez Id: 177
Gene Symbol: AGER
AGER
Q15109 advanced glycosylation end-product specific receptor cell adhesion molecule; receptor 232 0.472 0.724 3.4E-16 0.470 1.000 10 7 2003 2014
Entrez Id: 4795
Gene Symbol: NFKBIL1
NFKBIL1
Q9UBC1 NFKB inhibitor like 1 16 0.735 0.483 0.38 0.470 1.000 10 4 2001 2011
Entrez Id: 3899
Gene Symbol: AFF3
AFF3
P51826 AF4/FMR2 family member 3 transcription factor 39 0.672 0.448 1.00 0.470 1.000 8 1 2009 2013
Entrez Id: 5966
Gene Symbol: REL
REL
Q04864 REL proto-oncogene, NF-kB subunit nucleic acid binding; transcription factor 70 0.588 0.655 1.00 0.460 0.833 9 2 2009 2015
Entrez Id: 5788
Gene Symbol: PTPRC
PTPRC
P08575 protein tyrosine phosphatase, receptor type C hydrolase; phosphatase; receptor 196 0.488 0.759 1.00 0.460 0.833 8 1 1991 2016
Entrez Id: 7189
Gene Symbol: TRAF6
TRAF6
Q9Y4K3 TNF receptor associated factor 6 signaling molecule 120 0.528 0.724 1.00 0.460 1.000 8 1 2009 2015
Entrez Id: 5771
Gene Symbol: PTPN2
PTPN2
P17706 protein tyrosine phosphatase, non-receptor type 2 62 0.616 0.483 1.00 0.450 1.000 6 3 2012 2014
Entrez Id: 7297
Gene Symbol: TYK2
TYK2
P29597 tyrosine kinase 2 115 0.546 0.690 1.4E-06 0.440 0.750 6 2 2007 2016
Entrez Id: 79258
Gene Symbol: MMEL1
MMEL1
Q495T6 membrane metalloendopeptidase like 1 hydrolase; protease 44 0.672 0.517 5.4E-20 0.440 1.000 6 3 2008 2018