Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4763
Gene Symbol: NF1
NF1
P21359 neurofibromin 1 enzyme modulator 308 0.458 0.724 1.00 0.490 0.875 11 0 1994 2015
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
P11362 fibroblast growth factor receptor 1 623 0.388 0.759 1.00 0.440 1.000 6 5 1994 2016
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 650 0.352 0.862 1.8E-03 0.430 1.000 4 1 1994 2004
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11
Q06124 protein tyrosine phosphatase, non-receptor type 11 441 0.429 0.828 1.00 0.410 1.000 3 2 2004 2016
Entrez Id: 3020
Gene Symbol: H3F3A
H3F3A
P84243 H3 histone family member 3A nucleic acid binding 30 0.667 0.310 0.13 0.410 1.000 2 1 2014 2016
Entrez Id: 3418
Gene Symbol: IDH2
IDH2
P48735 isocitrate dehydrogenase (NADP(+)) 2, mitochondrial 237 0.469 0.655 0.87 0.400 1.000 25 2 2009 2018
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase 871 0.352 0.793 1.00 0.400 1.000 23 1 2008 2018
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 hydrolase; protease 790 0.339 0.862 7.0E-18 0.400 0.889 10 0 2000 2012
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha nucleic acid binding; transcription factor 586 0.367 0.793 0.97 0.370 0.857 8 0 2004 2016
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 nucleic acid binding; receptor; transcription factor 686 0.355 0.897 1.00 0.340 1.000 5 0 2001 2015
Entrez Id: 3082
Gene Symbol: HGF
HGF
P14210 hepatocyte growth factor hydrolase; protease 478 0.394 0.793 1.00 0.340 1.000 4 0 2001 2004
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase 407 0.405 0.793 0.99 0.330 1.000 4 0 2001 2013
Entrez Id: 57670
Gene Symbol: KIAA1549
KIAA1549
Q9HCM3 KIAA1549 25 0.676 0.138 0.99 0.330 1.000 4 0 2010 2014
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
P08254 matrix metallopeptidase 3 hydrolase; protease 309 0.439 0.793 4.9E-15 0.330 0.667 3 0 1997 2010
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch 1 389 0.415 0.759 1.00 0.320 1.000 3 0 2010 2013
Entrez Id: 8202
Gene Symbol: NCOA3
NCOA3
Q9Y6Q9 nuclear receptor coactivator 3 transcription factor; transferase 96 0.548 0.448 0.55 0.320 1.000 3 0 2011 2015
Entrez Id: 90
Gene Symbol: ACVR1
ACVR1
Q04771 activin A receptor type 1 kinase; receptor; transferase 102 0.573 0.552 0.38 0.320 1.000 2 0 2014 2015
Entrez Id: 4853
Gene Symbol: NOTCH2
NOTCH2
Q04721 notch 2 287 0.474 0.724 1.00 0.310 1.000 2 0 2011 2013
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase enzyme modulator 886 0.350 0.724 9.0E-04 0.310 2 0 2007 2013
Entrez Id: 9113
Gene Symbol: LATS1
LATS1
O95835 large tumor suppressor kinase 1 calcium-binding protein; kinase; transfer/carrier protein; transferase 54 0.602 0.379 1.00 0.310 1.000 1 0 2007 2007
Entrez Id: 26524
Gene Symbol: LATS2
LATS2
Q9NRM7 large tumor suppressor kinase 2 calcium-binding protein; kinase; transfer/carrier protein; transferase 53 0.616 0.448 0.99 0.310 1.000 1 0 2007 2007
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.300 0.966 150 5 1991 2016
Entrez Id: 10683
Gene Symbol: DLL3
DLL3
Q9NYJ7 delta like canonical Notch ligand 3 72 0.609 0.414 5.7E-05 0.300 1 0 2011 2011
Entrez Id: 23493
Gene Symbol: HEY2
HEY2
Q9UBP5 hes related family bHLH transcription factor with YRPW motif 2 transcription factor 57 0.609 0.517 0.90 0.300 1 0 2011 2011
Entrez Id: 23462
Gene Symbol: HEY1
HEY1
Q9Y5J3 hes related family bHLH transcription factor with YRPW motif 1 transcription factor 70 0.579 0.552 5.1E-02 0.300 1 0 2011 2011