Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.400 None 0.957 23 1 2000 2019
Entrez Id: 240
Gene Symbol: ALOX5
ALOX5
P09917 arachidonate 5-lipoxygenase Enzyme 342 0.447 0.885 1.2E-06 0.400 None 0.950 20 1 2003 2019
Entrez Id: 5320
Gene Symbol: PLA2G2A
PLA2G2A
P14555 phospholipase A2 group IIA Enzyme 215 0.488 0.808 9.7E-02 0.400 None 1.000 19 0 1999 2018
Entrez Id: 1535
Gene Symbol: CYBA
CYBA
P13498 cytochrome b-245 alpha chain 177 0.520 0.769 8.9E-06 0.400 None 1.000 16 1 2000 2019
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.400 None 0.933 15 0 2002 2019
Entrez Id: 857
Gene Symbol: CAV1
CAV1
Q03135 caveolin 1 Enzyme modulator 633 0.388 0.885 8.3E-03 0.400 None 1.000 15 0 2005 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.400 None 1.000 14 0 2007 2019
Entrez Id: 337
Gene Symbol: APOA4
APOA4
P06727 apolipoprotein A4 88 0.582 0.577 5.5E-06 0.400 None 1.000 13 0 1994 2019
Entrez Id: 4312
Gene Symbol: MMP1
MMP1
P03956 matrix metallopeptidase 1 Enzyme 589 0.385 0.885 7.7E-18 0.400 None 1.000 11 0 1998 2018
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
P09488 glutathione S-transferase mu 1 627 0.380 0.923 2.1E-03 0.380 None 0.889 9 0 2001 2019
Entrez Id: 241
Gene Symbol: ALOX5AP
ALOX5AP
P20292 arachidonate 5-lipoxygenase activating protein Enzyme 76 0.612 0.731 7.1E-02 0.370 None 1.000 8 0 2006 2018
Entrez Id: 5327
Gene Symbol: PLAT
PLAT
P00750 plasminogen activator, tissue type Enzyme 392 0.445 0.885 5.7E-05 0.360 None 1.000 7 0 1995 2010
Entrez Id: 9021
Gene Symbol: SOCS3
SOCS3
O14543 suppressor of cytokine signaling 3 Enzyme modulator 375 0.434 0.808 0.75 0.360 None 1.000 7 0 2008 2019
Entrez Id: 1269
Gene Symbol: CNR2
CNR2
P34972 cannabinoid receptor 2 G-protein coupled receptor 197 0.509 0.846 6.5E-06 0.360 None 1.000 6 0 2005 2019
Entrez Id: 196
Gene Symbol: AHR
AHR
P35869 aryl hydrocarbon receptor Transcription factor 532 0.410 0.923 1.00 0.350 None 1.000 6 0 2004 2019
Entrez Id: 64240
Gene Symbol: ABCG5
ABCG5
Q9H222 ATP binding cassette subfamily G member 5 Transporter 108 0.592 0.577 3.1E-21 0.350 None 1.000 6 0 2000 2014
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
P00441 superoxide dismutase 1 Enzyme 689 0.379 0.962 0.18 0.350 None 0.833 6 0 1997 2018
Entrez Id: 142
Gene Symbol: PARP1
PARP1
P09874 poly(ADP-ribose) polymerase 1 565 0.389 0.923 3.3E-04 0.340 None 1.000 5 0 2009 2019
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
P35228 nitric oxide synthase 2 783 0.364 0.923 4.0E-15 0.340 None 1.000 5 0 1999 2012
Entrez Id: 9971
Gene Symbol: NR1H4
NR1H4
Q96RI1 nuclear receptor subfamily 1 group H member 4 Nuclear receptor 187 0.513 0.808 9.4E-04 0.340 None 1.000 4 0 2018 2019
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
P04179 superoxide dismutase 2 Enzyme 668 0.379 0.923 0.15 0.330 None 1.000 5 0 2002 2017
Entrez Id: 3481
Gene Symbol: IGF2
IGF2
P01344 insulin like growth factor 2 604 0.390 0.885 4.4E-02 0.330 None 1.000 4 0 2002 2013
Entrez Id: 4048
Gene Symbol: LTA4H
LTA4H
P09960 leukotriene A4 hydrolase 63 0.617 0.654 3.0E-08 0.330 None 1.000 4 0 2006 2018
Entrez Id: 6351
Gene Symbol: CCL4
CCL4
P13236 Q8NHW4 C-C motif chemokine ligand 4 Signaling 276 0.466 0.923 0.24 0.330 None 1.000 4 0 2009 2020
Entrez Id: 3269
Gene Symbol: HRH1
HRH1
P35367 histamine receptor H1 G-protein coupled receptor 66 0.647 0.654 1.9E-06 0.310 None 1.000 2 0 1995 2014