Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
P01130 low density lipoprotein receptor 229 0.475 0.828 9.4E-24 0.700 0.964 148 4 1980 2018
Entrez Id: 183
Gene Symbol: AGT
AGT
P01019 angiotensinogen enzyme modulator 451 0.406 0.862 3.9E-08 0.600 0.979 51 0 1998 2018
Entrez Id: 177
Gene Symbol: AGER
AGER
Q15109 advanced glycosylation end-product specific receptor cell adhesion molecule; receptor 232 0.472 0.724 3.4E-16 0.600 1.000 24 0 1999 2017
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Q96EB6 sirtuin 1 hydrolase; nucleic acid binding 325 0.432 0.828 8.2E-02 0.600 0.929 14 0 2008 2017
Entrez Id: 3240
Gene Symbol: HP
HP
P00738 haptoglobin hydrolase; protease 228 0.461 0.793 7.4E-05 0.600 1.000 12 0 1990 2017
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 770 0.352 0.931 1.7E-03 0.500 0.952 345 3 1983 2018
Entrez Id: 1593
Gene Symbol: CYP27A1
CYP27A1
Q02318 cytochrome P450 family 27 subfamily A member 1 oxidoreductase 122 0.582 0.655 2.4E-19 0.450 1.000 5 0 2001 2014
Entrez Id: 5444
Gene Symbol: PON1
PON1
P27169 paraoxonase 1 324 0.443 0.828 9.0E-11 0.400 0.949 108 2 1998 2018
Entrez Id: 1401
Gene Symbol: CRP
CRP
P02741 C-reactive protein 470 0.399 0.862 3.7E-03 0.400 0.929 93 4 2000 2016
Entrez Id: 19
Gene Symbol: ABCA1
ABCA1
O95477 ATP binding cassette subfamily A member 1 transporter 236 0.484 0.793 3.5E-12 0.400 1.000 81 4 2000 2017
Entrez Id: 4018
Gene Symbol: LPA
LPA
P08519 lipoprotein(a) hydrolase; protease 198 0.489 0.655 5.8E-88 0.400 0.921 78 2 1987 2016
Entrez Id: 1071
Gene Symbol: CETP
CETP
P11597 cholesteryl ester transfer protein 116 0.555 0.655 1.0E-23 0.400 0.938 69 0 1995 2018
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor signaling molecule 1640 0.263 0.966 0.80 0.400 0.969 68 1 1997 2017
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
P13500 C-C motif chemokine ligand 2 signaling molecule 691 0.353 0.897 0.62 0.400 0.982 61 0 1996 2016
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 674 0.359 0.931 5.6E-09 0.400 0.930 60 2 2002 2018
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
P29474 nitric oxide synthase 3 467 0.401 0.862 8.9E-07 0.400 0.980 54 2 1999 2016
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 1330 0.287 0.966 0.34 0.400 0.956 49 1 1997 2017
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma nucleic acid binding; receptor; transcription factor 540 0.388 0.828 0.14 0.400 1.000 40 2 1999 2017
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
P05121 serpin family E member 1 enzyme modulator 506 0.384 0.793 4.7E-02 0.400 1.000 36 0 1992 2017
Entrez Id: 7412
Gene Symbol: VCAM1
VCAM1
P19320 vascular cell adhesion molecule 1 232 0.466 0.793 0.74 0.400 0.963 30 0 1997 2017
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A signaling molecule 1174 0.298 0.897 2.7E-05 0.400 0.963 29 0 1997 2017
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
P05362 intercellular adhesion molecule 1 489 0.386 0.897 3.8E-02 0.400 0.958 26 1 1997 2016
Entrez Id: 246
Gene Symbol: ALOX15
ALOX15
P16050 arachidonate 15-lipoxygenase oxidoreductase 115 0.543 0.690 4.0E-24 0.400 0.882 19 0 2005 2013
Entrez Id: 240
Gene Symbol: ALOX5
ALOX5
P09917 arachidonate 5-lipoxygenase oxidoreductase 214 0.482 0.724 1.5E-06 0.400 1.000 18 1 2004 2016
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 oxidoreductase 832 0.338 0.897 1.00 0.400 0.933 17 1 2000 2017