Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
P22607 fibroblast growth factor receptor 3 Kinase 654 0.391 0.846 1.6E-05 0.800 None 0.979 94 10 1999 2019
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase Enzyme modulator 698 0.378 0.885 8.0E-02 0.700 None 1.000 17 4 1983 2018
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.700 None 1.000 11 2 2000 2019
Entrez Id: 999
Gene Symbol: CDH1
CDH1
P12830 cadherin 1 508 0.401 0.808 0.15 0.690 None 1.000 11 1 2000 2016
Entrez Id: 472
Gene Symbol: ATM
ATM
Q13315 ATM serine/threonine kinase Kinase 684 0.374 0.885 5.6E-47 0.690 None 1.000 10 2 2008 2017
Entrez Id: 5925
Gene Symbol: RB1
RB1
P06400 RB transcriptional corepressor 1 Nucleic acid binding 339 0.444 0.885 1.00 0.610 None 1.000 1 2 2002 2002
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.600 None 0.970 230 5 1991 2020
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
P09211 glutathione S-transferase pi 1 610 0.383 0.923 1.4E-02 0.600 None 0.862 29 2 1995 2019
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 499 0.420 0.846 7.1E-20 0.600 None 1.000 21 4 2001 2016
Entrez Id: 1728
Gene Symbol: NQO1
NQO1
P15559 NAD(P)H quinone dehydrogenase 1 368 0.434 0.885 1.2E-09 0.600 None 0.947 19 2 1996 2017
Entrez Id: 10735
Gene Symbol: STAG2
STAG2
Q8N3U4 stromal antigen 2 Nucleic acid binding 132 0.568 0.731 1.00 0.560 None 1.000 7 0 2013 2018
Entrez Id: 7403
Gene Symbol: KDM6A
KDM6A
O15550 lysine demethylase 6A Epigenetic regulator 238 0.498 0.769 1.00 0.560 None 1.000 6 0 2011 2017
Entrez Id: 8000
Gene Symbol: PSCA
PSCA
O43653 prostate stem cell antigen 111 0.555 0.615 0.17 0.500 None 1.000 21 6 2001 2019
Entrez Id: 10460
Gene Symbol: TACC3
TACC3
Q9Y6A5 transforming acidic coiled-coil containing protein 3 62 0.615 0.615 2.7E-07 0.470 None 1.000 10 1 2010 2018
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
P09488 glutathione S-transferase mu 1 627 0.380 0.923 2.1E-03 0.400 None 0.938 112 2 1993 2019
Entrez Id: 10
Gene Symbol: NAT2
NAT2
P11245 N-acetyltransferase 2 Enzyme 311 0.451 0.885 3.3E-06 0.400 None 0.939 99 2 1995 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.400 None 1.000 64 1 1991 2020
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.400 None 1.000 57 1 1995 2019
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.400 None 0.968 31 3 1994 2020
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.400 None 1.000 30 1 1999 2019
Entrez Id: 406937
Gene Symbol: MIR145
MIR145
microRNA 145 366 0.431 0.846 0.400 None 0.923 26 0 2010 2019
Entrez Id: 7015
Gene Symbol: TERT
TERT
O14746 telomerase reverse transcriptase Enzyme 703 0.374 0.846 0.99 0.400 None 0.960 25 2 1999 2020
Entrez Id: 9
Gene Symbol: NAT1
NAT1
P18440 N-acetyltransferase 1 Enzyme 133 0.536 0.846 1.9E-14 0.400 None 0.750 24 0 1995 2018
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 821 0.344 0.923 1.00 0.400 None 1.000 21 0 1990 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.400 None 0.950 20 0 1991 2018