Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 641
Gene Symbol: BLM
BLM 		P54132 BLM RecQ like helicase 158 0.535 0.808 1.5E-15 1.000 definitive 0.994 159 128 1994 2020
Entrez Id: 7374
Gene Symbol: UNG
UNG 		P13051 uracil DNA glycosylase 66 0.617 0.654 1.7E-03 0.350 None 1.000 5 0 1986 1991
Entrez Id: 286053
Gene Symbol: NSMCE2
NSMCE2 		Q96MF7 NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase 50 0.682 0.615 3.8E-02 0.200 None 0 0
Entrez Id: 7486
Gene Symbol: WRN
WRN 		Q14191 WRN RecQ like helicase Enzyme 172 0.524 0.808 2.6E-34 0.100 None 1.000 14 1 1996 2017
Entrez Id: 3978
Gene Symbol: LIG1
LIG1 		P18858 DNA ligase 1 Enzyme 30 0.678 0.500 4.2E-03 0.100 None 0.900 10 0 1987 1994
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.080 None 0.875 8 0 1998 2007
Entrez Id: 9401
Gene Symbol: RECQL4
RECQL4 		O94761 RecQ like helicase 4 Enzyme 249 0.496 0.808 3.3E-35 0.050 None 1.000 5 0 1999 2017
Entrez Id: 472
Gene Symbol: ATM
ATM 		Q13315 ATM serine/threonine kinase Kinase 684 0.374 0.885 5.6E-47 0.050 None 1.000 5 0 2002 2018
Entrez Id: 164045
Gene Symbol: HFM1
HFM1 		A2PYH4 helicase for meiosis 1 39 0.659 0.615 4.7E-32 0.040 None 1.000 4 0 2002 2016
Entrez Id: 11073
Gene Symbol: TOPBP1
TOPBP1 		Q92547 DNA topoisomerase II binding protein 1 48 0.644 0.692 1.00 0.040 None 1.000 4 0 2013 2017
Entrez Id: 4609
Gene Symbol: MYC
MYC 		P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 821 0.344 0.923 1.00 0.030 None 1.000 3 0 1989 1995
Entrez Id: 2176
Gene Symbol: FANCC
FANCC 		Q00597 FA complementation group C 218 0.507 0.808 2.8E-13 0.030 None 1.000 3 0 2002 2012
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.030 None 1.000 3 0 2018 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2367 0.248 0.962 0.32 0.030 None 1.000 3 0 2017 2018
Entrez Id: 57697
Gene Symbol: FANCM
FANCM 		Q8IYD8 FA complementation group M Enzyme 147 0.543 0.731 2.4E-15 0.030 None 1.000 3 0 2009 2012
Entrez Id: 2242
Gene Symbol: FES
FES 		P07332 FES proto-oncogene, tyrosine kinase Kinase 101 0.593 0.769 3.8E-15 0.030 None 1.000 3 0 1994 1996
Entrez Id: 2993
Gene Symbol: GYPA
GYPA 		P02724 glycophorin A (MNS blood group) 136 0.538 0.885 1.1E-03 0.030 None 1.000 3 0 1989 1998
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2 		Q16236 nuclear factor, erythroid 2 like 2 Enzyme 823 0.357 0.885 3.6E-03 0.030 None 1.000 3 0 2018 2019
Entrez Id: 2551
Gene Symbol: GABPA
GABPA 		Q06546 GA binding protein transcription factor subunit alpha Transcription factor 632 0.379 0.885 1.00 0.030 None 1.000 3 0 2018 2019
Entrez Id: 5888
Gene Symbol: RAD51
RAD51 		Q06609 RAD51 recombinase 363 0.447 0.846 2.7E-02 0.030 None 1.000 3 0 1994 2000
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.020 None 1.000 2 0 2017 2017
Entrez Id: 80198
Gene Symbol: MUS81
MUS81 		Q96NY9 MUS81 structure-specific endonuclease subunit 32 0.686 0.462 8.8E-13 0.020 None 1.000 2 0 2008 2011
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		P51587 BRCA2 DNA repair associated Nucleic acid binding 656 0.379 0.846 2.4E-25 0.020 None 1.000 2 0 2004 2005
Entrez Id: 3014
Gene Symbol: H2AX
H2AX 		P16104 H2A.X variant histone Nucleic acid binding 212 0.484 0.808 0.18 0.020 None 1.000 2 0 2004 2007
Entrez Id: 9156
Gene Symbol: EXO1
EXO1 		Q9UQ84 exonuclease 1 Enzyme 87 0.578 0.692 8.1E-13 0.020 None 1.000 2 0 2017 2019