Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 nucleic acid binding; receptor; transcription factor 686 0.355 0.897 1.00 0.900 0.970 3087 24 1983 2018
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
P38398 BRCA1, DNA repair associated ligase 411 0.410 0.862 1.8E-28 0.900 strong 0.942 2277 131 1987 2018
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2, DNA repair associated nucleic acid binding 358 0.426 0.793 5.5E-24 0.900 strong 0.952 1290 40 1989 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.900 strong 0.966 999 17 1983 2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha kinase; transferase 835 0.341 0.897 1.00 0.900 0.968 318 6 2001 2018
Entrez Id: 580
Gene Symbol: BARD1
BARD1
Q99728 BRCA1 associated RING domain 1 54 0.624 0.379 2.2E-24 0.900 0.912 35 11 1997 2016
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 650 0.352 0.862 1.8E-03 0.800 0.971 3236 15 1987 2018
Entrez Id: 857
Gene Symbol: CAV1
CAV1
Q03135 caveolin 1 enzyme modulator; membrane traffic protein; structural protein; transmembrane receptor regulatory/adaptor protein 421 0.416 0.828 7.2E-03 0.800 0.986 71 0 1998 2017
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 calcium-binding protein; kinase; transfer/carrier protein; transferase 760 0.355 0.862 0.98 0.700 0.987 156 2 1999 2018
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog hydrolase; phosphatase 915 0.334 0.828 0.82 0.700 strong 0.971 143 1 1997 2018
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2
O96017 checkpoint kinase 2 195 0.494 0.621 1.2E-23 0.700 0.942 122 10 2001 2018
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Q86YC2 partner and localizer of BRCA2 122 0.569 0.552 7.3E-20 0.700 strong 0.968 96 10 2007 2018
Entrez Id: 83990
Gene Symbol: BRIP1
BRIP1
Q9BX63 BRCA1 interacting protein C-terminal helicase 1 nucleic acid binding 89 0.586 0.552 4.8E-17 0.700 0.977 45 4 2001 2017
Entrez Id: 2033
Gene Symbol: EP300
EP300
Q09472 E1A binding protein p300 nucleic acid binding; transcription factor; transferase 322 0.489 0.828 1.00 0.620 1.000 3 0 2004 2018
Entrez Id: 367
Gene Symbol: AR
AR
P10275 androgen receptor nucleic acid binding; receptor; transcription factor 564 0.380 0.793 0.98 0.600 0.940 153 2 1990 2018
Entrez Id: 472
Gene Symbol: ATM
ATM
Q13315 ATM serine/threonine kinase kinase; nucleic acid binding; transferase 486 0.401 0.862 6.0E-46 0.600 0.949 138 17 1996 2018
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
P21802 fibroblast growth factor receptor 2 665 0.398 0.759 1.00 0.600 0.948 98 10 1991 2018
Entrez Id: 5888
Gene Symbol: RAD51
RAD51
Q06609 RAD51 recombinase 174 0.517 0.724 3.3E-02 0.600 0.970 68 5 1998 2016
Entrez Id: 999
Gene Symbol: CDH1
CDH1
P12830 cadherin 1 322 0.432 0.759 0.11 0.600 0.962 58 8 1997 2017
Entrez Id: 142
Gene Symbol: PARP1
PARP1
P09874 poly(ADP-ribose) polymerase 1 312 0.432 0.862 5.5E-04 0.600 0.943 54 5 2005 2018
Entrez Id: 5744
Gene Symbol: PTHLH
PTHLH
P12272 parathyroid hormone like hormone 238 0.472 0.793 0.83 0.600 0.942 52 0 1992 2016
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
P46527 cyclin dependent kinase inhibitor 1B 334 0.424 0.724 0.66 0.600 1.000 44 2 1997 2017
Entrez Id: 2625
Gene Symbol: GATA3
GATA3
P23771 GATA binding protein 3 nucleic acid binding; transcription factor 208 0.477 0.793 0.90 0.600 0.951 41 2 1999 2018
Entrez Id: 3169
Gene Symbol: FOXA1
FOXA1
P55317 forkhead box A1 nucleic acid binding; transcription factor 68 0.590 0.586 0.24 0.600 1.000 41 0 2004 2018
Entrez Id: 2335
Gene Symbol: FN1
FN1
P02751 fibronectin 1 signaling molecule 461 0.399 0.828 1.2E-03 0.600 1.000 38 1 1997 2018