Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		P51587 BRCA2 DNA repair associated Nucleic acid binding 656 0.379 0.846 2.4E-25 0.100 None 1.000 22 0 1996 2011
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		P38398 BRCA1 DNA repair associated Enzyme 747 0.367 0.923 9.2E-29 0.100 None 0.941 17 1 1996 2017
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.100 None 1.000 15 0 1990 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.070 None 1.000 7 0 1995 2019
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.050 None 0.800 5 0 2005 2019
Entrez Id: 367
Gene Symbol: AR
AR 		P10275 androgen receptor Nuclear receptor 854 0.351 0.846 0.99 0.050 None 1.000 5 0 1999 2018
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		Q86YC2 partner and localizer of BRCA2 260 0.485 0.769 3.0E-19 0.040 None 1.000 4 0 2011 2017
Entrez Id: 5241
Gene Symbol: PGR
PGR 		P06401 progesterone receptor Nuclear receptor 392 0.426 0.885 5.1E-02 0.030 None 0.667 3 0 2002 2019
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		O96017 checkpoint kinase 2 Kinase 297 0.460 0.808 1.2E-24 0.030 None 1.000 3 0 2004 2009
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1 		P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 519 0.410 0.885 1.7E-05 0.030 None 1.000 3 0 2005 2018
Entrez Id: 1312
Gene Symbol: COMT
COMT 		P21964 catechol-O-methyltransferase Enzyme 622 0.400 0.923 1.1E-06 0.030 None 1.000 3 3 2004 2013
Entrez Id: 354
Gene Symbol: KLK3
KLK3 		P07288 kallikrein related peptidase 3 Enzyme 358 0.443 0.885 4.4E-06 0.020 None 0.500 2 0 1997 1998
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.020 None 1.000 2 0 1996 2013
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2 		P21802 fibroblast growth factor receptor 2 Kinase 731 0.380 0.808 1.00 0.020 None 1.000 2 0 2009 2013
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.020 None 1.000 2 0 2001 2012
Entrez Id: 5245
Gene Symbol: PHB
PHB 		P35232 prohibitin 177 0.511 0.846 0.76 0.020 None 1.000 2 0 2012 2013
Entrez Id: 1586
Gene Symbol: CYP17A1
CYP17A1 		P05093 cytochrome P450 family 17 subfamily A member 1 326 0.462 0.769 2.6E-04 0.020 None 0.500 2 0 2003 2005
Entrez Id: 11186
Gene Symbol: RASSF1
RASSF1 		Q9NS23 Ras association domain family member 1 Enzyme modulator 400 0.420 0.808 4.9E-06 0.020 None 1.000 2 0 2011 2012
Entrez Id: 5919
Gene Symbol: RARRES2
RARRES2 		Q99969 retinoic acid receptor responder 2 180 0.519 0.731 2.7E-05 0.010 None 1.000 1 0 2018 2018
Entrez Id: 5890
Gene Symbol: RAD51B
RAD51B 		O15315 RAD51 paralog B 126 0.556 0.769 2.1E-15 0.010 None 1.000 1 3 2016 2016
Entrez Id: 57534
Gene Symbol: MIB1
MIB1 		Q86YT6 mindbomb E3 ubiquitin protein ligase 1 Enzyme 329 0.438 0.769 3.4E-88 0.010 None < 0.001 1 0 2005 2005
Entrez Id: 85320
Gene Symbol: ABCC11
ABCC11 		Q96J66 ATP binding cassette subfamily C member 11 Transporter 91 0.565 0.769 4.0E-46 0.010 None 1.000 1 0 2011 2011
Entrez Id: 55655
Gene Symbol: NLRP2
NLRP2 		Q9NX02 NLR family pyrin domain containing 2 155 0.515 0.731 1.4E-38 0.010 None 1.000 1 0 2006 2006
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.010 None 1.000 1 0 2016 2016
Entrez Id: 8856
Gene Symbol: NR1I2
NR1I2 		O75469 nuclear receptor subfamily 1 group I member 2 Nuclear receptor 462 0.418 0.846 7.3E-09 0.010 None < 0.001 1 0 2007 2007