Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 367
Gene Symbol: AR
AR
P10275 androgen receptor nucleic acid binding; receptor; transcription factor 564 0.380 0.793 0.98 0.600 0.900 11 0 2003 2016
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog hydrolase; phosphatase 915 0.334 0.828 0.82 0.430 1.000 4 2 2009 2017
Entrez Id: 8405
Gene Symbol: SPOP
SPOP
O43791 speckle type BTB/POZ protein 37 0.656 0.207 1.00 0.420 1.000 3 9 2015 2017
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase 871 0.352 0.793 1.00 0.420 0.500 3 7 2006 2016
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 calcium-binding protein; kinase; transfer/carrier protein; transferase 760 0.355 0.862 0.98 0.420 1.000 3 1 2002 2016
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor 892 0.325 0.862 0.50 0.310 1.000 1 0 2008 2008
Entrez Id: 1316
Gene Symbol: KLF6
KLF6
Q99612 Kruppel like factor 6 nucleic acid binding; transcription factor 125 0.534 0.690 0.98 0.310 1.000 1 0 1996 1996
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Q86YC2 partner and localizer of BRCA2 122 0.569 0.552 7.3E-20 0.300 0 0
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2, DNA repair associated nucleic acid binding 358 0.426 0.793 5.5E-24 0.300 0 0
Entrez Id: 8312
Gene Symbol: AXIN1
AXIN1
O15169 axin 1 69 0.600 0.483 0.73 0.300 0 0
Entrez Id: 8379
Gene Symbol: MAD1L1
MAD1L1
Q9Y6D9 mitotic arrest deficient 1 like 1 56 0.609 0.483 3.8E-15 0.300 0 0
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2
O96017 checkpoint kinase 2 195 0.494 0.621 1.2E-23 0.300 0 0
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor nucleic acid binding; transcription factor 499 0.382 0.724 1.00 0.300 0 0
Entrez Id: 3169
Gene Symbol: FOXA1
FOXA1
P55317 forkhead box A1 nucleic acid binding; transcription factor 68 0.590 0.586 0.24 0.300 0 0
Entrez Id: 2048
Gene Symbol: EPHB2
EPHB2
P29323 EPH receptor B2 331 0.425 0.759 1.00 0.300 0 0
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
P38398 BRCA1, DNA repair associated ligase 411 0.410 0.862 1.8E-28 0.300 0 1
Entrez Id: 3066
Gene Symbol: HDAC2
HDAC2
Q92769 histone deacetylase 2 hydrolase; nucleic acid binding; oxidoreductase 119 0.534 0.759 1.00 0.300 0 0
Entrez Id: 2175
Gene Symbol: FANCA
FANCA
O15360 FA complementation group A 123 0.567 0.621 4.3E-68 0.300 0 0
Entrez Id: 472
Gene Symbol: ATM
ATM
Q13315 ATM serine/threonine kinase kinase; nucleic acid binding; transferase 486 0.401 0.862 6.0E-46 0.300 0 0
Entrez Id: 6790
Gene Symbol: AURKA
AURKA
O14965 aurora kinase A kinase; transferase 164 0.508 0.621 0.86 0.300 0 0
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.200 0.923 14 29 1992 2016
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 650 0.352 0.862 1.8E-03 0.160 0.833 7 1 1993 2016
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 891 0.321 0.828 0.38 0.110 1.000 2 1 2016 2016
Entrez Id: 354
Gene Symbol: KLK3
KLK3
P07288 kallikrein related peptidase 3 hydrolase; protease 153 0.519 0.793 4.8E-06 0.100 1.000 12 0 1991 2014
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
P09211 glutathione S-transferase pi 1 398 0.406 0.828 7.1E-02 0.100 1.000 11 1 1998 2016