Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.600 None 0.970 100 3 1991 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.400 None 0.938 16 0 1998 2020
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 499 0.420 0.846 7.1E-20 0.400 None 0.923 13 3 1999 2017
Entrez Id: 7507
Gene Symbol: XPA
XPA
P23025 XPA, DNA damage recognition and repair factor Nucleic acid binding 209 0.520 0.846 7.9E-05 0.380 None 1.000 10 0 1994 2018
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase Enzyme modulator 698 0.378 0.885 8.0E-02 0.350 None 1.000 12 0 1988 2015
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Q16236 nuclear factor, erythroid 2 like 2 Enzyme 823 0.357 0.885 3.6E-03 0.350 None 1.000 6 0 2008 2019
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
P30711 glutathione S-transferase theta 1 541 0.393 0.923 1.5E-04 0.340 None 0.750 4 0 2011 2015
Entrez Id: 7517
Gene Symbol: XRCC3
XRCC3
O43542 X-ray repair cross complementing 3 184 0.505 0.769 1.9E-10 0.330 None 0.800 5 0 2000 2014
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
Q03181 peroxisome proliferator activated receptor delta Nuclear receptor 197 0.513 0.846 0.99 0.330 None 1.000 5 0 2010 2019
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1
Q13635 patched 1 604 0.398 0.885 1.00 0.330 None 0.750 4 0 1998 2018
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch receptor 1 693 0.369 0.885 1.00 0.330 None 1.000 4 0 2008 2018
Entrez Id: 7299
Gene Symbol: TYR
TYR
P14679 tyrosinase Enzyme 281 0.473 0.808 5.0E-32 0.320 None 1.000 3 1 2008 2011
Entrez Id: 360
Gene Symbol: AQP3
AQP3
Q92482 aquaporin 3 (Gill blood group) Ion channel 124 0.546 0.769 0.13 0.320 None 1.000 3 0 2011 2019
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.320 None 1.000 3 0 2009 2019
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
P04179 superoxide dismutase 2 Enzyme 668 0.379 0.923 0.15 0.310 None 1.000 5 1 2001 2015
Entrez Id: 4953
Gene Symbol: ODC1
ODC1
P11926 ornithine decarboxylase 1 Enzyme 184 0.510 0.731 0.17 0.310 None 1.000 3 0 1989 2017
Entrez Id: 25913
Gene Symbol: POT1
POT1
Q9NUX5 protection of telomeres 1 Nucleic acid binding 107 0.560 0.731 0.85 0.310 None 1.000 2 0 2011 2014
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.310 None 1.000 2 0 1994 2005
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.310 None 1.000 2 0 2008 2008
Entrez Id: 1050
Gene Symbol: CEBPA
CEBPA
P49715 CCAAT enhancer binding protein alpha Transcription factor 201 0.496 0.692 0.55 0.310 None 1.000 2 0 2011 2012
Entrez Id: 434
Gene Symbol: ASIP
ASIP
P42127 agouti signaling protein Signaling 89 0.584 0.692 1.6E-02 0.310 None 1.000 2 0 2008 2009
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
P05019 insulin like growth factor 1 1206 0.318 0.885 0.27 0.310 None 1.000 2 0 2010 2013
Entrez Id: 6667
Gene Symbol: SP1
SP1
P08047 Sp1 transcription factor Nucleic acid binding 209 0.493 0.769 1.00 0.310 None 1.000 2 0 2011 2017
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
P07099 epoxide hydrolase 1 196 0.500 0.846 3.2E-09 0.310 None 1.000 1 1 2015 2015
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
P21860 erb-b2 receptor tyrosine kinase 3 Kinase 318 0.448 0.808 1.7E-15 0.310 None 1.000 1 0 2015 2015