Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 891 0.321 0.828 0.38 0.700 0.956 226 2 1994 2018
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
P18074 ERCC excision repair 2, TFIIH core complex helicase subunit nucleic acid binding 362 0.447 0.828 1.7E-20 0.700 1.000 15 3 2002 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.600 0.943 570 6 1991 2018
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase enzyme modulator 545 0.404 0.828 8.7E-02 0.600 0.969 34 1 1986 2016
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch 1 389 0.415 0.759 1.00 0.600 1.000 14 0 2008 2018
Entrez Id: 355
Gene Symbol: FAS
FAS
P25445 Fas cell surface death receptor 490 0.393 0.862 0.84 0.600 1.000 13 3 2000 2014
Entrez Id: 7508
Gene Symbol: XPC
XPC
Q01831 XPC complex subunit, DNA damage recognition and repair factor nucleic acid binding 159 0.523 0.655 2.7E-11 0.540 0.667 5 0 2005 2016
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor 892 0.325 0.862 0.50 0.500 0.965 251 6 1984 2018
Entrez Id: 4921
Gene Symbol: DDR2
DDR2
Q16832 discoidin domain receptor tyrosine kinase 2 128 0.579 0.621 0.88 0.480 1.000 10 4 2008 2018
Entrez Id: 51741
Gene Symbol: WWOX
WWOX
Q9NZC7 WW domain containing oxidoreductase oxidoreductase 214 0.489 0.655 7.0E-16 0.440 1.000 6 1 2002 2012
Entrez Id: 51151
Gene Symbol: SLC45A2
SLC45A2
Q9UMX9 solute carrier family 45 member 2 transporter 68 0.619 0.448 2.0E-06 0.430 1.000 4 3 2002 2017
Entrez Id: 2706
Gene Symbol: GJB2
GJB2
P29033 gap junction protein beta 2 cell junction protein 233 0.484 0.690 6.5E-16 0.420 1.000 2 0 2004 2011
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 enzyme modulator 589 0.365 0.828 0.90 0.400 0.987 85 0 1989 2018
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 oxidoreductase 832 0.338 0.897 1.00 0.400 0.963 70 0 1997 2017
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A signaling molecule 1174 0.298 0.897 2.7E-05 0.400 0.976 58 0 1998 2017
Entrez Id: 8626
Gene Symbol: TP63
TP63
Q9H3D4 tumor protein p63 transcription factor 475 0.419 0.759 1.00 0.400 0.976 49 0 2001 2016
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha kinase; transferase 835 0.341 0.897 1.00 0.400 0.977 48 2 2001 2018
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
P09488 glutathione S-transferase mu 1 423 0.403 0.828 2.0E-03 0.400 0.897 44 0 1993 2015
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 hydrolase; protease 790 0.339 0.862 7.0E-18 0.400 0.960 35 1 2000 2016
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 nucleic acid binding; transcription factor 706 0.358 0.862 1.00 0.400 0.964 34 0 2002 2016
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase enzyme modulator 886 0.350 0.724 9.0E-04 0.400 1.000 32 0 1990 2017
Entrez Id: 999
Gene Symbol: CDH1
CDH1
P12830 cadherin 1 322 0.432 0.759 0.11 0.400 0.909 27 0 2001 2017
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 signaling molecule 847 0.336 0.931 0.17 0.400 1.000 25 0 1993 2016
Entrez Id: 6317
Gene Symbol: SERPINB3
SERPINB3
P29508 serpin family B member 3 enzyme modulator 72 0.590 0.483 5.4E-16 0.400 1.000 23 0 1995 2013
Entrez Id: 6657
Gene Symbol: SOX2
SOX2
P48431 SRY-box 2 transcription factor 251 0.459 0.759 0.73 0.400 0.957 23 0 2009 2016