Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
P05305 endothelin 1 Signaling 679 0.380 0.846 0.46 0.310 None 1.000 2 0 2007 2018
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
P00749 plasminogen activator, urokinase Enzyme 439 0.425 0.923 2.3E-06 0.300 None 1.000 2 0 1976 2007
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.100 None 0.960 50 0 1992 2019
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.100 None 0.826 23 1 1995 2018
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.100 None 0.929 14 1 1998 2018
Entrez Id: 4854
Gene Symbol: NOTCH3
NOTCH3
Q9UM47 notch receptor 3 418 0.435 0.808 0.41 0.100 None 1.000 10 0 2002 2018
Entrez Id: 183
Gene Symbol: AGT
AGT
P01019 angiotensinogen Enzyme modulator 765 0.367 0.923 5.0E-08 0.070 None 1.000 7 3 1995 2018
Entrez Id: 4023
Gene Symbol: LPL
LPL
P06858 lipoprotein lipase Enzyme 290 0.474 0.808 1.3E-09 0.070 None 1.000 7 0 2000 2016
Entrez Id: 4018
Gene Symbol: LPA
LPA
P08519 lipoprotein(a) Enzyme 340 0.444 0.769 6.6E-89 0.070 None 1.000 7 0 1992 2018
Entrez Id: 57674
Gene Symbol: RNF213
RNF213
Q63HN8 ring finger protein 213 59 0.628 0.538 4.9E-55 0.060 None 1.000 6 1 2015 2019
Entrez Id: 5972
Gene Symbol: REN
REN
P00797 renin Enzyme 721 0.370 0.923 2.4E-07 0.060 None 1.000 6 1 1995 2019
Entrez Id: 3240
Gene Symbol: HP
HP
P00738 haptoglobin Enzyme 464 0.412 0.885 1.7E-05 0.050 None 0.800 5 0 2008 2019
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
P29474 nitric oxide synthase 3 706 0.378 0.885 6.7E-07 0.050 None 1.000 5 0 2000 2018
Entrez Id: 5444
Gene Symbol: PON1
PON1
P27169 paraoxonase 1 496 0.409 0.885 9.8E-11 0.050 None 0.600 5 2 2001 2018
Entrez Id: 3082
Gene Symbol: HGF
HGF
P14210 hepatocyte growth factor Enzyme 671 0.374 0.885 1.00 0.050 None 1.000 5 0 2001 2018
Entrez Id: 1282
Gene Symbol: COL4A1
COL4A1
P02462 collagen type IV alpha 1 chain 277 0.484 0.731 1.00 0.050 None 1.000 5 2 2009 2019
Entrez Id: 889
Gene Symbol: KRIT1
KRIT1
O00522 KRIT1 ankyrin repeat containing 201 0.500 0.808 6.9E-04 0.040 None 1.000 4 0 2014 2019
Entrez Id: 59
Gene Symbol: ACTA2
ACTA2
P62736 actin alpha 2, smooth muscle Cellular structure 200 0.508 0.846 0.93 0.040 None 1.000 4 1 2012 2018
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.040 None 1.000 4 0 1998 2016
Entrez Id: 1535
Gene Symbol: CYBA
CYBA
P13498 cytochrome b-245 alpha chain 177 0.520 0.769 8.9E-06 0.040 None 1.000 4 1 2000 2015
Entrez Id: 351
Gene Symbol: APP
APP
P05067 amyloid beta precursor protein Enzyme modulator 485 0.422 0.846 4.7E-02 0.040 None 0.750 4 0 1993 2019
Entrez Id: 2147
Gene Symbol: F2
F2
P00734 coagulation factor II, thrombin Enzyme 490 0.415 0.885 1.1E-03 0.040 None 1.000 4 1 1995 2011
Entrez Id: 338
Gene Symbol: APOB
APOB
P04114 apolipoprotein B 339 0.453 0.808 1.9E-16 0.030 None 1.000 3 2 1999 2007
Entrez Id: 1666
Gene Symbol: DECR1
DECR1
Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 399 0.426 0.885 4.5E-14 0.030 None 1.000 3 0 2000 2008
Entrez Id: 2717
Gene Symbol: GLA
GLA
P06280 galactosidase alpha 190 0.537 0.769 1.00 0.030 None 1.000 3 1 2005 2015