Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2131
Gene Symbol: EXT1
EXT1
Q16394 exostosin glycosyltransferase 1 Enzyme 205 0.522 0.769 1.00 0.800 None 0.947 19 2 1995 2018
Entrez Id: 1280
Gene Symbol: COL2A1
COL2A1
P02458 collagen type II alpha 1 chain 496 0.444 0.846 1.00 0.330 None 1.000 3 0 2013 2015
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
P42345 mechanistic target of rapamycin kinase Kinase 960 0.343 0.885 1.00 0.220 None 1.000 2 0 2012 2018
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
P22607 fibroblast growth factor receptor 3 Kinase 654 0.391 0.846 1.6E-05 0.210 None 1.000 2 1 2007 2013
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
O75874 isocitrate dehydrogenase (NADP(+)) 1 399 0.424 0.808 2.6E-12 0.200 None 1.000 26 1 2011 2020
Entrez Id: 3418
Gene Symbol: IDH2
IDH2
P48735 isocitrate dehydrogenase (NADP(+)) 2 380 0.434 0.808 0.88 0.200 None 1.000 19 0 2011 2019
Entrez Id: 8013
Gene Symbol: NR4A3
NR4A3
Q92570 nuclear receptor subfamily 4 group A member 3 Nuclear receptor 186 0.502 0.808 0.91 0.190 None 1.000 9 0 1999 2019
Entrez Id: 2132
Gene Symbol: EXT2
EXT2
Q93063 exostosin glycosyltransferase 2 Enzyme 137 0.576 0.654 1.3E-09 0.160 None 1.000 6 1 1999 2017
Entrez Id: 8148
Gene Symbol: TAF15
TAF15
Q92804 TATA-box binding protein associated factor 15 Nucleic acid binding 74 0.626 0.500 0.17 0.120 None 1.000 2 0 1999 2019
Entrez Id: 5745
Gene Symbol: PTH1R
PTH1R
Q03431 parathyroid hormone 1 receptor G-protein coupled receptor 187 0.544 0.731 0.57 0.110 None 1.000 1 0 2004 2004
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.100 None 1.000 24 0 1997 2019
Entrez Id: 4322
Gene Symbol: MMP13
MMP13
P45452 matrix metallopeptidase 13 Enzyme 328 0.452 0.923 7.9E-18 0.100 None 1.000 17 0 2001 2018
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.100 None 1.000 17 0 2004 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.100 None 1.000 16 0 1992 2018
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.100 None 1.000 10 0 2000 2019
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.100 None 0.900 10 0 1996 2020
Entrez Id: 4312
Gene Symbol: MMP1
MMP1
P03956 matrix metallopeptidase 1 Enzyme 589 0.385 0.885 7.7E-18 0.100 None 1.000 10 0 2003 2018
Entrez Id: 6662
Gene Symbol: SOX9
SOX9
P48436 SRY-box transcription factor 9 466 0.419 0.846 1.00 0.090 None 1.000 9 0 2002 2019
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
P08254 matrix metallopeptidase 3 Enzyme 473 0.408 0.885 5.7E-15 0.070 None 1.000 7 0 2007 2018
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.070 None 1.000 7 0 2004 2019
Entrez Id: 860
Gene Symbol: RUNX2
RUNX2
Q13950 RUNX family transcription factor 2 Transcription factor 405 0.437 0.846 0.95 0.070 None 1.000 7 0 2006 2018
Entrez Id: 1019
Gene Symbol: CDK4
CDK4
P11802 cyclin dependent kinase 4 Kinase 433 0.412 0.808 6.3E-02 0.060 None 1.000 6 0 1998 2019
Entrez Id: 2130
Gene Symbol: EWSR1
EWSR1
Q01844 EWS RNA binding protein 1 Nucleic acid binding 251 0.474 0.692 1.00 0.060 None 1.000 6 0 1995 2017
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.060 None 1.000 6 0 2003 2019
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
P08253 matrix metallopeptidase 2 Enzyme 1021 0.333 0.923 0.84 0.060 None 1.000 6 0 2007 2018