Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
Q9HC29 nucleotide binding oligomerization domain containing 2 hydrolase; nucleic acid binding; protease; transcription factor 265 0.458 0.862 1.6E-30 0.900 0.827 83 50 1998 2017
Entrez Id: 149233
Gene Symbol: IL23R
IL23R
Q5VWK5 interleukin 23 receptor defense/immunity protein; signaling molecule 170 0.505 0.724 7.0E-04 0.500 0.976 49 17 2006 2017
Entrez Id: 3586
Gene Symbol: IL10
IL10
P22301 interleukin 10 961 0.320 0.931 6.5E-03 0.500 0.905 46 1 1995 2017
Entrez Id: 9966
Gene Symbol: TNFSF15
TNFSF15
O95150 TNF superfamily member 15 signaling molecule 82 0.584 0.621 3.0E-03 0.500 0.941 21 8 2004 2016
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 nucleic acid binding; transcription factor 706 0.358 0.862 1.00 0.500 0.875 20 3 2008 2017
Entrez Id: 4485
Gene Symbol: MST1
MST1
P26927 macrophage stimulating 1 hydrolase; protease 150 0.525 0.724 6.2E-17 0.490 1.000 15 1 2008 2017
Entrez Id: 5771
Gene Symbol: PTPN2
PTPN2
P17706 protein tyrosine phosphatase, non-receptor type 2 62 0.616 0.483 1.00 0.470 1.000 9 4 2008 2017
Entrez Id: 2212
Gene Symbol: FCGR2A
FCGR2A
P12318 Fc fragment of IgG receptor IIa cell adhesion molecule 142 0.511 0.724 8.2E-05 0.450 1.000 9 3 2010 2017
Entrez Id: 345611
Gene Symbol: IRGM
IRGM
A1A4Y4 immunity related GTPase M 35 0.648 0.345 0.450 0.800 8 6 2009 2017
Entrez Id: 64170
Gene Symbol: CARD9
CARD9
Q9H257 caspase recruitment domain family member 9 52 0.624 0.448 9.8E-12 0.430 1.000 9 5 2008 2017
Entrez Id: 1611
Gene Symbol: DAP
DAP
P51397 death associated protein enzyme modulator 114 0.542 0.690 3.8E-03 0.420 1.000 5 3 2011 2017
Entrez Id: 3575
Gene Symbol: IL7R
IL7R
P16871 interleukin 7 receptor receptor 121 0.538 0.724 4.3E-07 0.420 1.000 3 2 2011 2016
Entrez Id: 2768
Gene Symbol: GNA12
GNA12
Q03113 G protein subunit alpha 12 enzyme modulator 82 0.594 0.690 0.97 0.410 1.000 6 2 2011 2017
Entrez Id: 400935
Gene Symbol: IL17REL
IL17REL
Q6ZVW7 interleukin 17 receptor E like 4 0.886 0.172 1.6E-03 0.410 1.000 3 3 2010 2017
Entrez Id: 219771
Gene Symbol: CCNY
CCNY
Q8ND76 cyclin Y 17 0.720 0.207 0.83 0.410 1.000 2 1 2008 2011
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor signaling molecule 1640 0.263 0.966 0.80 0.400 1.000 55 1 1996 2016
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
P01911 P01912 P04229 P13760 P13761 P20039 Q29974 Q30134 Q30167 Q5Y7A7 Q95IE3 Q9GIY3 Q9TQE0 major histocompatibility complex, class II, DR beta 1 defense/immunity protein 719 0.347 0.897 1.0E-03 0.400 0.884 43 0 1993 2015
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1035 0.312 0.931 0.13 0.400 0.870 28 1 1992 2015
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
P10145 C-X-C motif chemokine ligand 8 signaling molecule 758 0.342 0.862 0.400 0.947 20 0 1994 2016
Entrez Id: 159296
Gene Symbol: NKX2-3
NKX2-3
Q8TAU0 NK2 homeobox 3 nucleic acid binding; transcription factor 13 0.762 0.069 0.94 0.400 1.000 13 1 2008 2015
Entrez Id: 999
Gene Symbol: CDH1
CDH1
P12830 cadherin 1 322 0.432 0.759 0.11 0.400 0.900 10 0 1997 2016
Entrez Id: 113
Gene Symbol: ADCY7
ADCY7
P51828 adenylate cyclase 7 25 0.685 0.345 7.6E-07 0.400 3 2 2015 2017
Entrez Id: 3593
Gene Symbol: IL12B
IL12B
P29460 interleukin 12B defense/immunity protein; signaling molecule 166 0.506 0.793 1.2E-04 0.390 1.000 12 0 2008 2016
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
P05362 intercellular adhesion molecule 1 489 0.386 0.897 3.8E-02 0.390 0.857 10 2 1995 2016
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
O60674 Janus kinase 2 373 0.430 0.690 0.47 0.380 0.875 10 0 2009 2016