Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 434 0.423 0.923 2.0E-30 0.700 None 0.909 88 22 1998 2019
Entrez Id: 149233
Gene Symbol: IL23R
IL23R
Q5VWK5 interleukin 23 receptor Signaling 306 0.466 0.769 5.6E-04 0.700 None 0.982 56 20 2006 2020
Entrez Id: 5771
Gene Symbol: PTPN2
PTPN2
P17706 protein tyrosine phosphatase non-receptor type 2 134 0.538 0.692 1.00 0.680 None 1.000 10 5 2008 2016
Entrez Id: 6364
Gene Symbol: CCL20
CCL20
P78556 C-C motif chemokine ligand 20 Signaling 242 0.474 0.846 2.4E-04 0.640 None 1.000 7 1 2004 2017
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.600 None 0.971 170 3 1996 2020
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.600 None 0.959 49 2 1992 2020
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
P05362 intercellular adhesion molecule 1 737 0.364 0.962 3.5E-02 0.600 None 0.929 14 2 1995 2018
Entrez Id: 3663
Gene Symbol: IRF5
IRF5
Q13568 interferon regulatory factor 5 Transcription factor 226 0.489 0.731 9.0E-03 0.570 None 1.000 8 1 2007 2019
Entrez Id: 3586
Gene Symbol: IL10
IL10
P22301 interleukin 10 1679 0.281 0.923 5.9E-03 0.500 None 0.968 63 3 1995 2020
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1018 0.333 0.923 1.1E-03 0.500 None 0.885 52 2 1993 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.500 None 1.000 28 7 2008 2018
Entrez Id: 9966
Gene Symbol: TNFSF15
TNFSF15
O95150 TNF superfamily member 15 Signaling 143 0.531 0.692 2.8E-03 0.500 None 0.960 25 8 2004 2019
Entrez Id: 2212
Gene Symbol: FCGR2A
FCGR2A
P12318 Fc fragment of IgG receptor IIa Cell adhesion 227 0.480 0.769 2.0E-06 0.500 None 1.000 17 4 2009 2019
Entrez Id: 4485
Gene Symbol: MST1
MST1
P26927 macrophage stimulating 1 Enzyme 281 0.465 0.885 4.8E-19 0.470 None 1.000 13 1 2008 2017
Entrez Id: 345611
Gene Symbol: IRGM
IRGM
A1A4Y4 immunity related GTPase M 57 0.617 0.538 0.450 None 0.875 8 6 2009 2016
Entrez Id: 64170
Gene Symbol: CARD9
CARD9
Q9H257 caspase recruitment domain family member 9 103 0.566 0.654 8.1E-13 0.430 None 1.000 9 5 2008 2017
Entrez Id: 400935
Gene Symbol: IL17REL
IL17REL
Q6ZVW7 interleukin 17 receptor E like 5 0.861 0.192 1.9E-03 0.420 None 1.000 4 4 2010 2018
Entrez Id: 219771
Gene Symbol: CCNY
CCNY
Q8ND76 cyclin Y 26 0.711 0.269 0.81 0.420 None 1.000 3 1 2008 2011
Entrez Id: 3575
Gene Symbol: IL7R
IL7R
P16871 interleukin 7 receptor Receptor 231 0.487 0.769 3.8E-07 0.420 None 1.000 3 1 2011 2016
Entrez Id: 2768
Gene Symbol: GNA12
GNA12
Q03113 G protein subunit alpha 12 Enzyme modulator 130 0.547 0.769 0.97 0.410 None 1.000 6 2 2011 2017
Entrez Id: 113
Gene Symbol: ADCY7
ADCY7
P51828 adenylate cyclase 7 38 0.656 0.462 9.5E-07 0.410 None 1.000 3 2 2015 2017
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.400 None 0.921 38 8 1992 2018
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
P10145 C-X-C motif chemokine ligand 8 Signaling 1254 0.310 0.962 2.7E-04 0.400 None 1.000 28 0 1994 2020
Entrez Id: 4353
Gene Symbol: MPO
MPO
P05164 myeloperoxidase Enzyme 653 0.377 0.923 7.1E-15 0.400 None 1.000 15 0 2010 2019
Entrez Id: 159296
Gene Symbol: NKX2-3
NKX2-3
Q8TAU0 NK2 homeobox 3 Transcription factor 22 0.716 0.231 0.95 0.400 None 1.000 14 2 2008 2014