Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
P13500 C-C motif chemokine ligand 2 signaling molecule 691 0.353 0.897 0.62 0.580 0.750 10 0 2001 2016
Entrez Id: 959
Gene Symbol: CD40LG
CD40LG
P29965 CD40 ligand signaling molecule 291 0.447 0.828 0.73 0.510 1.000 3 0 2006 2013
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme hydrolase; protease 624 0.367 0.897 1.6E-37 0.400 0.896 97 2 1992 2016
Entrez Id: 4018
Gene Symbol: LPA
LPA
P08519 lipoprotein(a) hydrolase; protease 198 0.489 0.655 5.8E-88 0.400 0.968 64 0 1986 2018
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
P01130 low density lipoprotein receptor 229 0.475 0.828 9.4E-24 0.400 0.967 63 3 1987 2017
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
P29474 nitric oxide synthase 3 467 0.401 0.862 8.9E-07 0.400 0.964 59 1 1996 2018
Entrez Id: 5444
Gene Symbol: PON1
PON1
P27169 paraoxonase 1 324 0.443 0.828 9.0E-11 0.400 0.809 50 2 1996 2018
Entrez Id: 1401
Gene Symbol: CRP
CRP
P02741 C-reactive protein 470 0.399 0.862 3.7E-03 0.400 0.894 48 5 1999 2016
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A signaling molecule 1174 0.298 0.897 2.7E-05 0.400 0.925 42 2 1996 2018
Entrez Id: 335
Gene Symbol: APOA1
APOA1
P02647 apolipoprotein A1 255 0.463 0.759 5.5E-04 0.400 0.889 37 0 1986 2017
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 nucleic acid binding; receptor; transcription factor 686 0.355 0.897 1.00 0.400 0.960 27 2 1998 2018
Entrez Id: 255738
Gene Symbol: PCSK9
PCSK9
Q8NBP7 proprotein convertase subtilisin/kexin type 9 hydrolase; protease 101 0.572 0.552 1.9E-17 0.400 0.955 24 3 2005 2016
Entrez Id: 116519
Gene Symbol: APOA5
APOA5
Q6Q788 apolipoprotein A5 67 0.609 0.483 9.0E-10 0.400 0.913 24 2 2001 2018
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
P09601 heme oxygenase 1 oxidoreductase 460 0.403 0.862 7.9E-03 0.400 0.867 15 0 2002 2015
Entrez Id: 345
Gene Symbol: APOC3
APOC3
P02656 apolipoprotein C3 107 0.552 0.586 9.4E-03 0.400 0.917 13 0 1997 2016
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 674 0.359 0.931 5.6E-09 0.400 0.818 11 2 2003 2015
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
P08254 matrix metallopeptidase 3 hydrolase; protease 309 0.439 0.793 4.9E-15 0.380 0.875 8 0 1996 2006
Entrez Id: 11173
Gene Symbol: ADAMTS7
ADAMTS7
Q9UKP4 ADAM metallopeptidase with thrombospondin type 1 motif 7 enzyme modulator; extracellular matrix protein; hydrolase; protease 26 0.696 0.379 3.2E-13 0.370 1.000 8 1 2011 2015
Entrez Id: 4049
Gene Symbol: LTA
LTA
P01374 lymphotoxin alpha signaling molecule 228 0.463 0.862 0.56 0.370 0.857 7 0 1998 2010
Entrez Id: 9365
Gene Symbol: KL
KL
Q9UEF7 klotho hydrolase 182 0.495 0.621 2.2E-04 0.360 1.000 6 0 2003 2017
Entrez Id: 6272
Gene Symbol: SORT1
SORT1
Q99523 sortilin 1 receptor; transporter 51 0.624 0.448 1.00 0.350 1.000 6 0 2008 2016
Entrez Id: 51129
Gene Symbol: ANGPTL4
ANGPTL4
Q9BY76 angiopoietin like 4 signaling molecule 95 0.567 0.621 2.1E-11 0.350 1.000 6 1 2008 2016
Entrez Id: 3667
Gene Symbol: IRS1
IRS1
P35568 insulin receptor substrate 1 137 0.532 0.621 3.5E-02 0.350 1.000 5 1 1999 2016
Entrez Id: 6943
Gene Symbol: TCF21
TCF21
O43680 transcription factor 21 46 0.633 0.448 0.84 0.340 1.000 6 0 2011 2016
Entrez Id: 221692
Gene Symbol: PHACTR1
PHACTR1
Q9C0D0 phosphatase and actin regulator 1 enzyme modulator 22 0.752 0.172 0.64 0.340 1.000 6 0 2011 2017