Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 770 0.352 0.931 1.7E-03 0.500 0.961 154 4 1983 2018
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 699 0.354 0.828 1.2E-09 0.500 0.863 106 5 1991 2018
Entrez Id: 4018
Gene Symbol: LPA
LPA
P08519 lipoprotein(a) hydrolase; protease 198 0.489 0.655 5.8E-88 0.500 0.970 105 3 1986 2018
Entrez Id: 338
Gene Symbol: APOB
APOB
P04114 apolipoprotein B 232 0.477 0.724 1.6E-16 0.500 0.987 79 2 1986 2017
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
P01130 low density lipoprotein receptor 229 0.475 0.828 9.4E-24 0.500 0.945 78 3 1986 2017
Entrez Id: 7941
Gene Symbol: PLA2G7
PLA2G7
Q13093 phospholipase A2 group VII hydrolase 75 0.584 0.552 8.9E-22 0.500 0.893 30 2 1997 2017
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
Q9NQB0 transcription factor 7 like 2 145 0.538 0.621 0.99 0.450 0.750 8 2 2008 2017
Entrez Id: 6927
Gene Symbol: HNF1A
HNF1A
P20823 HNF1 homeobox A nucleic acid binding; transcription factor 187 0.515 0.621 0.96 0.450 1.000 8 3 1998 2017
Entrez Id: 64240
Gene Symbol: ABCG5
ABCG5
Q9H222 ATP binding cassette subfamily G member 5 transporter 91 0.602 0.414 3.5E-21 0.410 1.000 3 2 2009 2015
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme hydrolase; protease 624 0.367 0.897 1.6E-37 0.400 0.862 145 2 1992 2017
Entrez Id: 5444
Gene Symbol: PON1
PON1
P27169 paraoxonase 1 324 0.443 0.828 9.0E-11 0.400 0.893 88 5 1997 2018
Entrez Id: 51530
Gene Symbol: ZC3HC1
ZC3HC1
Q86WB0 zinc finger C3HC-type containing 1 14 0.773 0.207 1.6E-04 0.400 5 1 2011 2017
Entrez Id: 8701
Gene Symbol: DNAH11
DNAH11
Q96DT5 dynein axonemal heavy chain 11 cytoskeletal protein; hydrolase 35 0.690 0.345 8.8E-57 0.400 2 1 2009 2011
Entrez Id: 22808
Gene Symbol: MRAS
MRAS
O14807 muscle RAS oncogene homolog enzyme modulator 21 0.727 0.276 0.92 0.400 2 2 2011 2017
Entrez Id: 1524
Gene Symbol: CX3CR1
CX3CR1
P49238 C-X3-C motif chemokine receptor 1 185 0.496 0.828 5.7E-02 0.390 1.000 9 0 2001 2013
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
P08254 matrix metallopeptidase 3 hydrolase; protease 309 0.439 0.793 4.9E-15 0.380 0.875 8 1 1996 2010
Entrez Id: 3667
Gene Symbol: IRS1
IRS1
P35568 insulin receptor substrate 1 137 0.532 0.621 3.5E-02 0.350 1.000 6 0 1999 2017
Entrez Id: 948
Gene Symbol: CD36
CD36
P16671 CD36 molecule receptor 180 0.505 0.828 6.6E-61 0.350 1.000 5 1 2000 2012
Entrez Id: 79001
Gene Symbol: VKORC1
VKORC1
Q9BQB6 vitamin K epoxide reductase complex subunit 1 oxidoreductase 59 0.639 0.655 0.16 0.340 0.750 4 1 2006 2013
Entrez Id: 8997
Gene Symbol: KALRN
KALRN
O60229 kalirin RhoGEF kinase signaling molecule 23 0.720 0.207 1.00 0.320 1.000 2 0 2007 2016
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
P00749 plasminogen activator, urokinase hydrolase; protease 325 0.434 0.690 2.1E-06 0.310 1.000 3 0 1992 2015
Entrez Id: 2100
Gene Symbol: ESR2
ESR2
Q92731 estrogen receptor 2 nucleic acid binding; receptor; transcription factor 297 0.445 0.828 5.4E-08 0.310 1.000 2 1 2008 2009
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 hydrolase; protease 790 0.339 0.862 7.0E-18 0.300 1.000 16 0 2003 2017
Entrez Id: 80212
Gene Symbol: CCDC92
CCDC92
Q53HC0 coiled-coil domain containing 92 9 0.886 0.103 0.18 0.300 1 0 2017 2017
Entrez Id: 407975
Gene Symbol: MIR17HG
MIR17HG
Q75NE6 miR-17-92a-1 cluster host gene 137 0.522 0.759 0.300 1 0 2017 2017