Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 64127
Gene Symbol: NOD2
NOD2 		Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 434 0.423 0.923 2.0E-30 1.000 moderate 0.937 714 75 1998 2019
Entrez Id: 55054
Gene Symbol: ATG16L1
ATG16L1 		Q676U5 autophagy related 16 like 1 120 0.543 0.769 0.96 0.700 None 0.953 150 23 2001 2020
Entrez Id: 149233
Gene Symbol: IL23R
IL23R 		Q5VWK5 interleukin 23 receptor Signaling 306 0.466 0.769 5.6E-04 0.700 None 0.950 120 29 2006 2020
Entrez Id: 3586
Gene Symbol: IL10
IL10 		P22301 interleukin 10 1679 0.281 0.923 5.9E-03 0.700 strong 0.962 78 5 1996 2020
Entrez Id: 345611
Gene Symbol: IRGM
IRGM 		A1A4Y4 immunity related GTPase M 57 0.617 0.538 0.700 None 0.939 66 11 2007 2020
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1 		P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1018 0.333 0.923 1.1E-03 0.700 None 0.880 25 5 1994 2019
Entrez Id: 7297
Gene Symbol: TYK2
TYK2 		P29597 tyrosine kinase 2 Kinase 172 0.505 0.769 4.5E-08 0.620 None 0.800 5 4 2010 2016
Entrez Id: 3593
Gene Symbol: IL12B
IL12B 		P29460 interleukin 12B Signaling 249 0.480 0.885 1.1E-04 0.600 None 1.000 19 3 2004 2018
Entrez Id: 7099
Gene Symbol: TLR4
TLR4 		O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.500 None 0.940 50 6 2004 2019
Entrez Id: 6583
Gene Symbol: SLC22A4
SLC22A4 		Q9H015 solute carrier family 22 member 4 Transporter 90 0.603 0.769 1.8E-08 0.500 None 0.896 48 5 2003 2017
Entrez Id: 6774
Gene Symbol: STAT3
STAT3 		P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.500 strong 0.969 32 9 2008 2019
Entrez Id: 5771
Gene Symbol: PTPN2
PTPN2 		P17706 protein tyrosine phosphatase non-receptor type 2 134 0.538 0.692 1.00 0.500 None 1.000 31 8 2007 2018
Entrez Id: 120892
Gene Symbol: LRRK2
LRRK2 		Q5S007 leucine rich repeat kinase 2 Kinase 231 0.510 0.808 2.6E-30 0.500 None 1.000 24 10 2008 2019
Entrez Id: 2524
Gene Symbol: FUT2
FUT2 		Q10981 fucosyltransferase 2 Enzyme 126 0.552 0.731 5.3E-14 0.500 None 1.000 17 6 2010 2020
Entrez Id: 4485
Gene Symbol: MST1
MST1 		P26927 macrophage stimulating 1 Enzyme 281 0.465 0.885 4.8E-19 0.500 None 1.000 17 1 2008 2018
Entrez Id: 3717
Gene Symbol: JAK2
JAK2 		O60674 Janus kinase 2 Kinase 644 0.385 0.885 0.65 0.500 None 1.000 12 3 2008 2018
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA 		P01589 interleukin 2 receptor subunit alpha Receptor 540 0.389 0.885 5.5E-02 0.460 None 1.000 11 6 1999 2018
Entrez Id: 4689
Gene Symbol: NCF4
NCF4 		Q15080 neutrophil cytosolic factor 4 58 0.644 0.615 9.0E-08 0.450 None 0.714 7 1 2007 2017
Entrez Id: 60468
Gene Symbol: BACH2
BACH2 		Q9BYV9 BTB domain and CNC homolog 2 130 0.539 0.731 1.00 0.440 None 1.000 8 2 2010 2018
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3 		P84022 SMAD family member 3 Transcription factor 470 0.415 0.923 0.80 0.430 None 1.000 8 3 2010 2019
Entrez Id: 219771
Gene Symbol: CCNY
CCNY 		Q8ND76 cyclin Y 26 0.711 0.269 0.81 0.430 None 1.000 4 2 2008 2011
Entrez Id: 64167
Gene Symbol: ERAP2
ERAP2 		Q6P179 endoplasmic reticulum aminopeptidase 2 Enzyme 58 0.615 0.577 1.0E-28 0.420 None 1.000 7 6 2010 2017
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.400 None 0.950 281 5 1996 2020
Entrez Id: 1401
Gene Symbol: CRP
CRP 		P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.400 None 0.989 94 1 2001 2020
Entrez Id: 3458
Gene Symbol: IFNG
IFNG 		P01579 interferon gamma 1519 0.288 0.962 0.47 0.400 None 0.930 43 2 1993 2020