Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
Q9HC29 nucleotide binding oligomerization domain containing 2 hydrolase; nucleic acid binding; protease; transcription factor 265 0.458 0.862 1.6E-30 0.900 0.909 653 63 1998 2018
Entrez Id: 55054
Gene Symbol: ATG16L1
ATG16L1
Q676U5 autophagy related 16 like 1 66 0.586 0.586 0.94 0.500 0.927 124 14 2001 2018
Entrez Id: 149233
Gene Symbol: IL23R
IL23R
Q5VWK5 interleukin 23 receptor defense/immunity protein; signaling molecule 170 0.505 0.724 7.0E-04 0.500 0.923 107 27 2006 2017
Entrez Id: 3586
Gene Symbol: IL10
IL10
P22301 interleukin 10 961 0.320 0.931 6.5E-03 0.500 0.945 58 4 1996 2018
Entrez Id: 345611
Gene Symbol: IRGM
IRGM
A1A4Y4 immunity related GTPase M 35 0.648 0.345 0.500 0.913 53 10 2007 2018
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 674 0.359 0.931 5.6E-09 0.500 0.833 38 2 2004 2018
Entrez Id: 5771
Gene Symbol: PTPN2
PTPN2
P17706 protein tyrosine phosphatase, non-receptor type 2 62 0.616 0.483 1.00 0.500 1.000 26 6 2007 2017
Entrez Id: 4485
Gene Symbol: MST1
MST1
P26927 macrophage stimulating 1 hydrolase; protease 150 0.525 0.724 6.2E-17 0.500 1.000 15 1 2008 2017
Entrez Id: 2524
Gene Symbol: FUT2
FUT2
Q10981 fucosyltransferase 2 transferase 76 0.579 0.586 6.5E-14 0.480 1.000 14 5 2010 2017
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
P01589 interleukin 2 receptor subunit alpha receptor 361 0.419 0.828 5.2E-02 0.460 1.000 11 6 2000 2018
Entrez Id: 4689
Gene Symbol: NCF4
NCF4
Q15080 neutrophil cytosolic factor 4 40 0.690 0.345 8.6E-08 0.450 0.600 7 1 2008 2017
Entrez Id: 60468
Gene Symbol: BACH2
BACH2
Q9BYV9 BTB domain and CNC homolog 2 69 0.596 0.586 1.00 0.420 1.000 6 2 2010 2017
Entrez Id: 219771
Gene Symbol: CCNY
CCNY
Q8ND76 cyclin Y 17 0.720 0.207 0.83 0.420 1.000 3 2 2008 2011
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
P84022 SMAD family member 3 transcription factor 273 0.462 0.862 0.84 0.410 1.000 6 3 2010 2017
Entrez Id: 64167
Gene Symbol: ERAP2
ERAP2
Q6P179 endoplasmic reticulum aminopeptidase 2 hydrolase; protease 28 0.685 0.345 9.7E-28 0.410 1.000 6 4 2010 2017
Entrez Id: 7297
Gene Symbol: TYK2
TYK2
P29597 tyrosine kinase 2 115 0.546 0.690 1.4E-06 0.410 1.000 4 2 2010 2017
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor signaling molecule 1640 0.263 0.966 0.80 0.400 0.944 113 3 1996 2018
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 1330 0.287 0.966 0.34 0.400 0.897 32 0 1992 2018
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
P01579 interferon gamma 901 0.323 0.897 0.47 0.400 0.885 29 1 1993 2016
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
P01911 P01912 P04229 P13760 P13761 P20039 Q29974 Q30134 Q30167 Q5Y7A7 Q95IE3 Q9GIY3 Q9TQE0 major histocompatibility complex, class II, DR beta 1 defense/immunity protein 719 0.347 0.897 1.0E-03 0.400 0.870 23 0 1995 2015
Entrez Id: 3593
Gene Symbol: IL12B
IL12B
P29460 interleukin 12B defense/immunity protein; signaling molecule 166 0.506 0.793 1.2E-04 0.400 0.941 17 2 2005 2016
Entrez Id: 159296
Gene Symbol: NKX2-3
NKX2-3
Q8TAU0 NK2 homeobox 3 nucleic acid binding; transcription factor 13 0.762 0.069 0.94 0.400 0.929 16 2 2007 2015
Entrez Id: 1401
Gene Symbol: CRP
CRP
P02741 C-reactive protein 470 0.399 0.862 3.7E-03 0.400 0.929 15 0 2001 2015
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
Q96P20 NLR family pyrin domain containing 3 366 0.435 0.862 7.0E-04 0.400 0.857 14 3 2004 2015
Entrez Id: 6556
Gene Symbol: SLC11A1
SLC11A1
P49279 solute carrier family 11 member 1 transporter 107 0.537 0.793 3.5E-19 0.400 0.700 11 1 1997 2016