Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3630
Gene Symbol: INS
INS
P01308 insulin 405 0.445 0.923 0.30 0.700 None 0.963 163 3 1981 2020
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 0.500 None 0.935 108 6 1999 2019
Entrez Id: 1356
Gene Symbol: CP
CP
P00450 ceruloplasmin Enzyme 283 0.466 0.846 4.2E-10 0.460 None 1.000 7 2 1995 2017
Entrez Id: 5879
Gene Symbol: RAC1
RAC1
P63000 Rac family small GTPase 1 Enzyme modulator 415 0.429 0.962 0.76 0.450 None 1.000 6 0 2013 2018
Entrez Id: 26060
Gene Symbol: APPL1
APPL1
Q9UKG1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 63 0.626 0.500 0.80 0.430 strong 1.000 3 4 2015 2017
Entrez Id: 1968
Gene Symbol: EIF2S3
EIF2S3
P41091 eukaryotic translation initiation factor 2 subunit gamma Enzyme 107 0.604 0.731 0.96 0.410 strong 1.000 2 1 2002 2017
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
Q15848 adiponectin, C1Q and collagen domain containing 679 0.376 0.885 4.6E-09 0.400 None 0.967 152 9 2002 2020
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Q96EB6 sirtuin 1 Epigenetic regulator 675 0.378 0.885 8.7E-02 0.400 None 1.000 55 1 2007 2019
Entrez Id: 5444
Gene Symbol: PON1
PON1
P27169 paraoxonase 1 496 0.409 0.885 9.8E-11 0.400 None 0.977 43 2 1998 2020
Entrez Id: 847
Gene Symbol: CAT
CAT
P04040 catalase Enzyme 794 0.359 0.962 1.6E-10 0.400 None 0.976 41 0 2000 2020
Entrez Id: 3667
Gene Symbol: IRS1
IRS1
P35568 insulin receptor substrate 1 233 0.488 0.769 2.4E-02 0.400 None 0.969 32 1 1995 2019
Entrez Id: 2335
Gene Symbol: FN1
FN1
P02751 fibronectin 1 Signaling 724 0.365 0.962 1.4E-03 0.400 None 1.000 19 0 1990 2019
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
P00441 superoxide dismutase 1 Enzyme 689 0.379 0.962 0.18 0.400 None 1.000 14 0 2001 2019
Entrez Id: 8856
Gene Symbol: NR1I2
NR1I2
O75469 nuclear receptor subfamily 1 group I member 2 Nuclear receptor 462 0.418 0.846 7.3E-09 0.400 None 1.000 14 0 2010 2020
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.400 None 0.923 13 1 2004 2019
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
P48357 leptin receptor Signaling 416 0.433 0.808 0.99 0.400 None 1.000 12 1 1996 2019
Entrez Id: 5443
Gene Symbol: POMC
POMC
P01189 proopiomelanocortin 873 0.356 0.846 1.2E-04 0.400 None 0.833 12 0 1996 2019
Entrez Id: 4508
Gene Symbol: ATP6
ATP6
P00846 ATP synthase F0 subunit 6 Transporter 226 0.541 0.731 0.400 None 1.000 1 0 2008 2008
Entrez Id: 8639
Gene Symbol: AOC3
AOC3
Q16853 amine oxidase copper containing 3 106 0.561 0.769 6.3E-11 0.390 None 1.000 10 0 2003 2019
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
P01589 interleukin 2 receptor subunit alpha Receptor 540 0.389 0.885 5.5E-02 0.380 None 1.000 9 0 2002 2018
Entrez Id: 5080
Gene Symbol: PAX6
PAX6
P26367 paired box 6 340 0.450 0.769 1.00 0.380 strong 1.000 8 0 2002 2019
Entrez Id: 1536
Gene Symbol: CYBB
CYBB
P04839 cytochrome b-245 beta chain Ion channel 343 0.452 0.885 1.00 0.360 None 1.000 7 0 2009 2019
Entrez Id: 9970
Gene Symbol: NR1I3
NR1I3
Q14994 nuclear receptor subfamily 1 group I member 3 Nuclear receptor 318 0.448 0.846 3.5E-08 0.350 None 1.000 6 0 2010 2019
Entrez Id: 4217
Gene Symbol: MAP3K5
MAP3K5
Q99683 mitogen-activated protein kinase kinase kinase 5 Kinase 170 0.513 0.808 0.52 0.340 None 1.000 5 1 2006 2018
Entrez Id: 4502
Gene Symbol: MT2A
MT2A
P02795 metallothionein 2A 117 0.553 0.808 1.2E-05 0.340 None 1.000 4 1 2007 2018