Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3172
Gene Symbol: HNF4A
HNF4A
P41235 hepatocyte nuclear factor 4 alpha nucleic acid binding; receptor; transcription factor 236 0.486 0.690 0.16 0.900 0.930 136 16 1992 2017
Entrez Id: 3667
Gene Symbol: IRS1
IRS1
P35568 insulin receptor substrate 1 137 0.532 0.621 3.5E-02 0.900 0.941 108 6 1993 2017
Entrez Id: 5078
Gene Symbol: PAX4
PAX4
O43316 paired box 4 23 0.707 0.207 4.3E-04 0.900 0.929 14 2 1999 2015
Entrez Id: 5506
Gene Symbol: PPP1R3A
PPP1R3A
Q16821 protein phosphatase 1 regulatory subunit 3A enzyme modulator 52 0.681 0.379 1.7E-15 0.900 0.917 13 2 1994 2016
Entrez Id: 208
Gene Symbol: AKT2
AKT2
P31751 AKT serine/threonine kinase 2 calcium-binding protein; kinase; transfer/carrier protein; transferase 163 0.512 0.655 0.61 0.830 1.000 6 1 2001 2014
Entrez Id: 6517
Gene Symbol: SLC2A4
SLC2A4
P14672 solute carrier family 2 member 4 90 0.564 0.586 3.2E-05 0.800 0.958 52 1 1990 2016
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
Q9NQB0 transcription factor 7 like 2 145 0.538 0.621 0.99 0.700 0.961 310 24 2006 2018
Entrez Id: 2645
Gene Symbol: GCK
GCK
P35557 glucokinase 160 0.547 0.586 0.66 0.700 0.922 156 5 1992 2018
Entrez Id: 6927
Gene Symbol: HNF1A
HNF1A
P20823 HNF1 homeobox A nucleic acid binding; transcription factor 187 0.515 0.621 0.96 0.700 0.938 109 14 1995 2018
Entrez Id: 11132
Gene Symbol: CAPN10
CAPN10
Q9HC96 calpain 10 calcium-binding protein; hydrolase; protease 46 0.630 0.483 2.2E-12 0.700 0.939 105 4 2000 2016
Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1
Q5VV42 CDK5 regulatory subunit associated protein 1 like 1 56 0.639 0.483 1.5E-02 0.700 0.987 103 90 2007 2018
Entrez Id: 3643
Gene Symbol: INSR
INSR
P06213 insulin receptor 338 0.459 0.724 2.0E-05 0.700 0.932 95 5 1985 2016
Entrez Id: 3767
Gene Symbol: KCNJ11
KCNJ11
Q14654 potassium voltage-gated channel subfamily J member 11 179 0.542 0.552 9.8E-03 0.700 0.961 89 10 1996 2017
Entrez Id: 3651
Gene Symbol: PDX1
PDX1
P52945 pancreatic and duodenal homeobox 1 135 0.557 0.483 2.0E-02 0.700 0.909 37 7 1998 2016
Entrez Id: 6928
Gene Symbol: HNF1B
HNF1B
P35680 HNF1 homeobox B nucleic acid binding; transcription factor 152 0.526 0.621 1.00 0.700 0.962 37 9 1999 2017
Entrez Id: 6514
Gene Symbol: SLC2A2
SLC2A2
P11168 solute carrier family 2 member 2 89 0.596 0.552 3.3E-08 0.700 0.833 30 5 1991 2017
Entrez Id: 4760
Gene Symbol: NEUROD1
NEUROD1
Q13562 neuronal differentiation 1 nucleic acid binding; transcription factor 84 0.572 0.690 0.77 0.700 0.842 21 3 1999 2016
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2, apoptosis regulator signaling molecule 987 0.312 0.862 0.57 0.610 1.000 4 1 2007 2017
Entrez Id: 9479
Gene Symbol: MAPK8IP1
MAPK8IP1
Q9UQF2 mitogen-activated protein kinase 8 interacting protein 1 enzyme modulator; signaling molecule 12 0.799 0.207 1.00 0.610 1.000 1 1 2000 2000
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
Q15848 adiponectin, C1Q and collagen domain containing 201 0.485 0.724 5.0E-09 0.600 0.929 117 15 1999 2018
Entrez Id: 3630
Gene Symbol: INS
INS
P01308 insulin 309 0.458 0.828 0.32 0.600 0.900 105 2 1985 2016
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor signaling molecule 1640 0.263 0.966 0.80 0.600 0.956 93 7 1995 2018
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
Q9UBK2 PPARG coactivator 1 alpha transcription factor 191 0.497 0.828 1.00 0.600 0.935 67 3 2002 2018
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 498 0.400 0.793 0.39 0.600 0.893 62 0 1995 2015
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
P48357 leptin receptor defense/immunity protein; signaling molecule 264 0.474 0.793 1.00 0.600 0.875 49 5 1979 2018