Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 498 0.400 0.793 0.39 0.600 1.000 18 0 2003 2017
Entrez Id: 338
Gene Symbol: APOB
APOB
P04114 apolipoprotein B 232 0.477 0.724 1.6E-16 0.600 1.000 17 0 2001 2015
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Q96EB6 sirtuin 1 hydrolase; nucleic acid binding 325 0.432 0.828 8.2E-02 0.600 1.000 14 0 2010 2018
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
P01130 low density lipoprotein receptor 229 0.475 0.828 9.4E-24 0.530 1.000 13 0 1997 2016
Entrez Id: 7351
Gene Symbol: UCP2
UCP2
P55851 uncoupling protein 2 148 0.530 0.690 1.3E-10 0.520 1.000 4 0 2000 2012
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
P05181 cytochrome P450 family 2 subfamily E member 1 212 0.473 0.759 3.9E-07 0.520 1.000 4 0 2003 2011
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog hydrolase; phosphatase 915 0.334 0.828 0.82 0.510 1.000 3 0 2008 2016
Entrez Id: 847
Gene Symbol: CAT
CAT
P04040 catalase oxidoreductase 446 0.397 0.828 1.9E-10 0.510 < 0.001 3 0 1995 2011
Entrez Id: 80339
Gene Symbol: PNPLA3
PNPLA3
Q9NST1 patatin like phospholipase domain containing 3 hydrolase; transferase 85 0.584 0.552 4.0E-07 0.400 0.945 56 1 2008 2018
Entrez Id: 6720
Gene Symbol: SREBF1
SREBF1
P36956 sterol regulatory element binding transcription factor 1 90 0.570 0.517 1.9E-02 0.400 1.000 23 0 2003 2017
Entrez Id: 2875
Gene Symbol: GPT
GPT
P24298 glutamic--pyruvic transaminase transferase 155 0.510 0.828 7.1E-19 0.400 0.875 21 0 2001 2015
Entrez Id: 5465
Gene Symbol: PPARA
PPARA
Q07869 peroxisome proliferator activated receptor alpha nucleic acid binding; receptor; transcription factor 247 0.465 0.793 3.7E-02 0.400 1.000 19 0 2006 2018
Entrez Id: 4547
Gene Symbol: MTTP
MTTP
P55157 microsomal triglyceride transfer protein transfer/carrier protein; transporter 144 0.526 0.690 1.4E-05 0.400 1.000 17 0 2001 2017
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor signaling molecule 1640 0.263 0.966 0.80 0.390 1.000 10 0 2003 2014
Entrez Id: 26291
Gene Symbol: FGF21
FGF21
Q9NSA1 fibroblast growth factor 21 signaling molecule 60 0.614 0.483 3.0E-02 0.380 1.000 9 0 2011 2016
Entrez Id: 9971
Gene Symbol: NR1H4
NR1H4
Q96RI1 nuclear receptor subfamily 1 group H member 4 nucleic acid binding; receptor; transcription factor 149 0.522 0.655 1.3E-03 0.350 1.000 6 0 2009 2017
Entrez Id: 10062
Gene Symbol: NR1H3
NR1H3
Q13133 nuclear receptor subfamily 1 group H member 3 nucleic acid binding; receptor; transcription factor 48 0.621 0.517 0.91 0.340 1.000 5 0 2011 2015
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 674 0.359 0.931 5.6E-09 0.330 1.000 5 0 2008 2016
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
Q03181 peroxisome proliferator activated receptor delta nucleic acid binding; receptor; transcription factor 122 0.551 0.621 0.99 0.330 1.000 4 0 2008 2013
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Q16236 nuclear factor, erythroid 2 like 2 cytoskeletal protein; hydrolase; nucleic acid binding; transcription factor 376 0.420 0.862 3.5E-03 0.330 1.000 4 0 2012 2017
Entrez Id: 7494
Gene Symbol: XBP1
XBP1
P17861 X-box binding protein 1 113 0.540 0.690 2.3E-02 0.320 1.000 3 0 2014 2016
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
P48357 leptin receptor defense/immunity protein; signaling molecule 264 0.474 0.793 1.00 0.320 1.000 3 0 2008 2018
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
P05121 serpin family E member 1 enzyme modulator 506 0.384 0.793 4.7E-02 0.320 1.000 3 0 2008 2012
Entrez Id: 407040
Gene Symbol: MIR34A
MIR34A
microRNA 34a 220 0.470 0.759 0.320 1.000 3 0 2014 2016
Entrez Id: 8856
Gene Symbol: NR1I2
NR1I2
O75469 nuclear receptor subfamily 1 group I member 2 nucleic acid binding; receptor; transcription factor 263 0.455 0.793 6.2E-09 0.320 1.000 2 1 2013 2016