Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.420 None 0.667 3 4 1997 2018
Entrez Id: 3417
Gene Symbol: IDH1
IDH1 		O75874 isocitrate dehydrogenase (NADP(+)) 1 399 0.424 0.808 2.6E-12 0.360 None 1.000 6 2 2011 2018
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		P48735 isocitrate dehydrogenase (NADP(+)) 2 380 0.434 0.808 0.88 0.340 None 1.000 4 2 2011 2017
Entrez Id: 10413
Gene Symbol: YAP1
YAP1 		P46937 Yes associated protein 1 Enzyme modulator 374 0.432 0.808 1.00 0.300 None 1.000 1 0 2019 2019
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		P31749 AKT serine/threonine kinase 1 Kinase 1250 0.311 0.962 0.98 0.180 None 0.875 8 0 2013 2020
Entrez Id: 2776
Gene Symbol: GNAQ
GNAQ 		P50148 G protein subunit alpha q Enzyme modulator 219 0.516 0.808 0.98 0.140 None 1.000 4 3 2017 2019
Entrez Id: 7428
Gene Symbol: VHL
VHL 		P40337 von Hippel-Lindau tumor suppressor Enzyme 372 0.443 0.846 8.0E-02 0.130 None 1.000 3 0 1999 2005
Entrez Id: 2324
Gene Symbol: FLT4
FLT4 		P35916 fms related receptor tyrosine kinase 4 Kinase 306 0.457 0.808 1.00 0.120 None 1.000 2 1 2002 2013
Entrez Id: 2736
Gene Symbol: GLI2
GLI2 		P10070 GLI family zinc finger 2 351 0.446 0.846 0.97 0.110 None 1.000 1 0 2017 2017
Entrez Id: 2475
Gene Symbol: MTOR
MTOR 		P42345 mechanistic target of rapamycin kinase Kinase 960 0.343 0.885 1.00 0.110 None 1.000 1 0 2013 2013
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1 		P11362 fibroblast growth factor receptor 1 Kinase 816 0.362 0.885 1.00 0.110 None 1.000 1 0 2017 2017
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.110 None 1.000 1 0 2007 2007
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.110 None 1.000 1 1 2019 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.100 None 0.962 26 1 1999 2019
Entrez Id: 7994
Gene Symbol: KAT6A
KAT6A 		Q92794 lysine acetyltransferase 6A Enzyme 129 0.560 0.769 1.00 0.100 None 1.000 1 1 2015 2015
Entrez Id: 8506
Gene Symbol: CNTNAP1
CNTNAP1 		P78357 contactin associated protein 1 166 0.554 0.577 3.4E-05 0.100 None 1.000 1 1 2017 2017
Entrez Id: 7468
Gene Symbol: NSD2
NSD2 		O96028 nuclear receptor binding SET domain protein 2 Epigenetic regulator 224 0.507 0.769 1.00 0.100 None 0 0
Entrez Id: 23135
Gene Symbol: KDM6B
KDM6B 		O15054 lysine demethylase 6B Epigenetic regulator 173 0.514 0.808 1.00 0.100 None 0 0
Entrez Id: 6496
Gene Symbol: SIX3
SIX3 		O95343 SIX homeobox 3 Transcription factor 117 0.560 0.692 0.95 0.100 None 0 0
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		P21912 succinate dehydrogenase complex iron sulfur subunit B Enzyme 316 0.474 0.846 2.4E-04 0.100 None 0 0
Entrez Id: 1991
Gene Symbol: ELANE
ELANE 		P08246 elastase, neutrophil expressed Enzyme 346 0.447 0.846 1.2E-03 0.100 None 0 0
Entrez Id: 23592
Gene Symbol: LEMD3
LEMD3 		Q9Y2U8 LEM domain containing 3 112 0.582 0.731 1.00 0.100 None 0 0
Entrez Id: 6392
Gene Symbol: SDHD
SDHD 		O14521 succinate dehydrogenase complex subunit D Transporter 348 0.472 0.885 0.34 0.100 None 0 0
Entrez Id: 6469
Gene Symbol: SHH
SHH 		Q15465 sonic hedgehog signaling molecule 303 0.461 0.846 0.98 0.100 None 0 0
Entrez Id: 6125
Gene Symbol: RPL5
RPL5 		P46777 ribosomal protein L5 Nucleic acid binding 92 0.617 0.615 1.00 0.100 None 0 1