Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2161
Gene Symbol: F12
F12
P00748 coagulation factor XII Enzyme 87 0.612 0.577 8.3E-08 0.700 strong 0.952 21 2 1984 2019
Entrez Id: 710
Gene Symbol: SERPING1
SERPING1
P05155 serpin family G member 1 Enzyme modulator 207 0.507 0.769 0.96 0.600 strong 0.991 335 2 1971 2020
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
P01042 kininogen 1 Enzyme modulator 279 0.481 0.885 3.2E-10 0.400 None 0.983 60 0 1983 2020
Entrez Id: 5340
Gene Symbol: PLG
PLG
P00747 plasminogen Enzyme 586 0.389 0.923 1.0E-02 0.200 None 1.000 13 2 1978 2019
Entrez Id: 3818
Gene Symbol: KLKB1
KLKB1
P03952 kallikrein B1 Enzyme 88 0.604 0.692 6.3E-13 0.100 None 1.000 18 0 1985 2019
Entrez Id: 2870
Gene Symbol: GRK6
GRK6
P43250 G protein-coupled receptor kinase 6 Kinase 51 0.670 0.654 4.9E-04 0.100 None 1.000 8 2 2006 2015
Entrez Id: 5267
Gene Symbol: SERPINA4
SERPINA4
P29622 serpin family A member 4 Enzyme modulator 45 0.641 0.654 9.7E-09 0.090 None 1.000 9 0 2006 2019
Entrez Id: 404203
Gene Symbol: SPINK6
SPINK6
Q6UWN8 serine peptidase inhibitor Kazal type 6 16 0.760 0.385 3.5E-07 0.090 None 1.000 9 0 2006 2019
Entrez Id: 284
Gene Symbol: ANGPT1
ANGPT1
Q15389 angiopoietin 1 Signaling 340 0.446 0.808 0.95 0.040 None 1.000 4 1 2018 2019
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.030 None 1.000 3 0 2012 2016
Entrez Id: 5176
Gene Symbol: SERPINF1
SERPINF1
P36955 serpin family F member 1 Enzyme modulator 294 0.460 0.846 7.8E-08 0.020 None 1.000 2 0 1984 1985
Entrez Id: 5345
Gene Symbol: SERPINF2
SERPINF2
P08697 serpin family F member 2 Enzyme modulator 104 0.575 0.808 1.4E-02 0.020 None 1.000 2 0 1984 1985
Entrez Id: 5443
Gene Symbol: POMC
POMC
P01189 proopiomelanocortin 873 0.356 0.846 1.2E-04 0.020 None 1.000 2 0 1989 1992
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
P30411 bradykinin receptor B2 G-protein coupled receptor 105 0.585 0.808 0.12 0.020 None 1.000 2 0 1994 1997
Entrez Id: 3516
Gene Symbol: RBPJ
RBPJ
Q06330 recombination signal binding protein for immunoglobulin kappa J region Nucleic acid binding 161 0.518 0.808 1.00 0.020 None 1.000 2 0 2017 2018
Entrez Id: 716
Gene Symbol: C1S
C1S
P09871 complement C1s Enzyme 43 0.705 0.462 6.8E-04 0.020 None 1.000 2 0 2010 2019
Entrez Id: 717
Gene Symbol: C2
C2
P06681 complement C2 71 0.617 0.692 1.3E-16 0.020 None 0.500 2 0 1983 1985
Entrez Id: 9118
Gene Symbol: INA
INA
Q16352 internexin neuronal intermediate filament protein alpha 58 0.633 0.500 1.5E-08 0.020 None 1.000 2 0 1984 1984
Entrez Id: 23676
Gene Symbol: SMPX
SMPX
Q9UHP9 small muscle protein X-linked 37 0.682 0.500 0.62 0.020 None 1.000 2 0 2017 2018
Entrez Id: 1401
Gene Symbol: CRP
CRP
P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.020 None 1.000 2 0 2014 2019
Entrez Id: 1444
Gene Symbol: CSHL1
CSHL1
Q14406 chorionic somatomammotropin hormone like 1 Signaling 49 0.647 0.577 3.1E-12 0.020 None 1.000 2 0 2017 2018
Entrez Id: 6738
Gene Symbol: RO60
RO60
P10155 Ro60, Y RNA binding protein Nucleic acid binding 61 0.610 0.692 0.58 0.010 None 1.000 1 0 1997 1997
Entrez Id: 10404
Gene Symbol: CPQ
CPQ
Q9Y646 carboxypeptidase Q Enzyme 87 0.579 0.769 1.3E-14 0.010 None 1.000 1 0 2016 2016
Entrez Id: 10747
Gene Symbol: MASP2
MASP2
O00187 mannan binding lectin serine peptidase 2 Enzyme 86 0.582 0.692 3.0E-14 0.010 None 1.000 1 0 2006 2006
Entrez Id: 5972
Gene Symbol: REN
REN
P00797 renin Enzyme 721 0.370 0.923 2.4E-07 0.010 None 1.000 1 0 1985 1985