Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 498 0.400 0.793 0.39 0.700 0.964 33 0 1997 2012
Entrez Id: 3643
Gene Symbol: INSR
INSR
P06213 insulin receptor 338 0.459 0.724 2.0E-05 0.700 limited 0.870 25 0 1989 2016
Entrez Id: 2746
Gene Symbol: GLUD1
GLUD1
P00367 glutamate dehydrogenase 1 oxidoreductase 47 0.636 0.552 7.3E-03 0.590 strong 1.000 10 0 1998 2016
Entrez Id: 3172
Gene Symbol: HNF4A
HNF4A
P41235 hepatocyte nuclear factor 4 alpha nucleic acid binding; receptor; transcription factor 236 0.486 0.690 0.16 0.470 strong 1.000 8 1 2007 2015
Entrez Id: 3767
Gene Symbol: KCNJ11
KCNJ11
Q14654 potassium voltage-gated channel subfamily J member 11 179 0.542 0.552 9.8E-03 0.470 strong 1.000 7 1 2000 2011
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
P48357 leptin receptor defense/immunity protein; signaling molecule 264 0.474 0.793 1.00 0.440 1.000 9 0 1986 2015
Entrez Id: 6833
Gene Symbol: ABCC8
ABCC8
Q09428 ATP binding cassette subfamily C member 8 transporter 232 0.508 0.690 2.7E-23 0.400 strong 1.000 28 1 1997 2017
Entrez Id: 3630
Gene Symbol: INS
INS
P01308 insulin 309 0.458 0.828 0.32 0.390 0.833 13 0 1984 2015
Entrez Id: 2641
Gene Symbol: GCG
GCG
P01275 glucagon 152 0.529 0.655 2.5E-02 0.380 0.875 9 0 1986 2018
Entrez Id: 4160
Gene Symbol: MC4R
MC4R
P32245 melanocortin 4 receptor receptor 84 0.580 0.586 9.1E-04 0.370 0.714 8 3 2004 2013
Entrez Id: 2645
Gene Symbol: GCK
GCK
P35557 glucokinase 160 0.547 0.586 0.66 0.370 strong 1.000 7 0 2004 2016
Entrez Id: 3667
Gene Symbol: IRS1
IRS1
P35568 insulin receptor substrate 1 137 0.532 0.621 3.5E-02 0.360 0.833 6 0 2000 2017
Entrez Id: 3033
Gene Symbol: HADH
HADH
Q16836 hydroxyacyl-CoA dehydrogenase 75 0.652 0.414 8.0E-05 0.340 strong 1.000 4 0 2005 2013
Entrez Id: 5770
Gene Symbol: PTPN1
PTPN1
P18031 protein tyrosine phosphatase, non-receptor type 1 87 0.569 0.621 0.78 0.320 1.000 3 0 1999 2017
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
P29474 nitric oxide synthase 3 467 0.401 0.862 8.9E-07 0.320 1.000 2 1 2008 2009
Entrez Id: 2876
Gene Symbol: GPX1
GPX1
P07203 glutathione peroxidase 1 oxidoreductase 172 0.498 0.759 4.5E-05 0.310 1.000 3 0 2004 2010
Entrez Id: 1281
Gene Symbol: COL3A1
COL3A1
P02461 collagen type III alpha 1 chain 222 0.510 0.759 1.00 0.310 1.000 1 0 2010 2010
Entrez Id: 6927
Gene Symbol: HNF1A
HNF1A
P20823 HNF1 homeobox A nucleic acid binding; transcription factor 187 0.515 0.621 0.96 0.310 strong 1.000 1 0 2012 2012
Entrez Id: 2176
Gene Symbol: FANCC
FANCC
Q00597 FA complementation group C 120 0.569 0.655 2.6E-13 0.310 1.000 1 0 2014 2014
Entrez Id: 2200
Gene Symbol: FBN1
FBN1
P35555 fibrillin 1 calcium-binding protein; cell adhesion molecule; extracellular matrix protein; signaling molecule 413 0.469 0.690 1.00 0.310 1.000 1 0 2010 2010
Entrez Id: 93587
Gene Symbol: TRMT10A
TRMT10A
Q8TBZ6 tRNA methyltransferase 10A nucleic acid binding; transferase 23 0.752 0.345 1.4E-10 0.300 limited 1 0 2015 2015
Entrez Id: 1831
Gene Symbol: TSC22D3
TSC22D3
Q99576 TSC22 domain family member 3 34 0.667 0.483 0.42 0.300 1 0 2012 2012
Entrez Id: 79661
Gene Symbol: NEIL1
NEIL1
Q96FI4 nei like DNA glycosylase 1 47 0.636 0.586 5.1E-07 0.300 1 0 2006 2006
Entrez Id: 2175
Gene Symbol: FANCA
FANCA
O15360 FA complementation group A 123 0.567 0.621 4.3E-68 0.300 1 0 2014 2014
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
P09601 heme oxygenase 1 oxidoreductase 460 0.403 0.862 7.9E-03 0.300 1 0 2009 2009