Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
P05305 endothelin 1 signaling molecule 419 0.417 0.828 0.46 0.530 9 0 1995 2011
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
P31645 solute carrier family 6 member 4 transporter 329 0.446 0.724 0.26 0.530 7 0 2001 2009
Entrez Id: 4879
Gene Symbol: NPPB
NPPB
P16860 natriuretic peptide B 112 0.567 0.552 9.1E-06 0.530 6 0 2005 2011
Entrez Id: 94
Gene Symbol: ACVRL1
ACVRL1
P37023 activin A receptor like type 1 kinase; receptor; transferase 130 0.570 0.621 8.2E-04 0.510 3 0 2004 2016
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
P29474 nitric oxide synthase 3 467 0.401 0.862 8.9E-07 0.500 4 0 2006 2011
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha nucleic acid binding; transcription factor 586 0.367 0.793 0.97 0.500 3 0 2005 2010
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
P13500 C-C motif chemokine ligand 2 signaling molecule 691 0.353 0.897 0.62 0.500 3 0 1998 2008
Entrez Id: 1910
Gene Symbol: EDNRB
EDNRB
P24530 endothelin receptor type B 223 0.492 0.793 1.2E-02 0.500 3 0 2004 2008
Entrez Id: 4773
Gene Symbol: NFATC2
NFATC2
Q13469 nuclear factor of activated T cells 2 transcription factor 74 0.588 0.517 1.00 0.500 2 0 2007 2017
Entrez Id: 959
Gene Symbol: CD40LG
CD40LG
P29965 CD40 ligand signaling molecule 291 0.447 0.828 0.73 0.500 2 0 2005 2015
Entrez Id: 240
Gene Symbol: ALOX5
ALOX5
P09917 arachidonate 5-lipoxygenase oxidoreductase 214 0.482 0.724 1.5E-06 0.500 2 0 1996 2004
Entrez Id: 3741
Gene Symbol: KCNA5
KCNA5
P22460 potassium voltage-gated channel subfamily A member 5 43 0.648 0.414 1.2E-03 0.500 2 0 2010 2017
Entrez Id: 659
Gene Symbol: BMPR2
BMPR2
Q13873 bone morphogenetic protein receptor type 2 kinase; receptor; transferase 96 0.573 0.552 1.00 0.370 16 0 2002 2014
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme hydrolase; protease 624 0.367 0.897 1.6E-37 0.320 3 0 2003 2004
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
P01135 transforming growth factor alpha signaling molecule 290 0.447 0.724 0.74 0.310 2 0 2003 2008
Entrez Id: 1317
Gene Symbol: SLC31A1
SLC31A1
O15431 solute carrier family 31 member 1 37 0.681 0.379 7.1E-02 0.300 1 0 2016 2016
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor signaling molecule 1640 0.263 0.966 0.80 0.300 1 0 1990 1990
Entrez Id: 7166
Gene Symbol: TPH1
TPH1
P17752 tryptophan hydroxylase 1 62 0.611 0.586 3.2E-07 0.300 1 0 2008 2008
Entrez Id: 2308
Gene Symbol: FOXO1
FOXO1
Q12778 forkhead box O1 190 0.490 0.724 1.00 0.300 1 0 2017 2017
Entrez Id: 440275
Gene Symbol: EIF2AK4
EIF2AK4
Q9P2K8 eukaryotic translation initiation factor 2 alpha kinase 4 kinase; transferase 37 0.696 0.414 1.4E-15 0.300 1 0 2014 2014
Entrez Id: 3778
Gene Symbol: KCNMA1
KCNMA1
Q12791 potassium calcium-activated channel subfamily M alpha 1 99 0.572 0.586 1.00 0.300 1 0 2016 2016
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
P10145 C-X-C motif chemokine ligand 8 signaling molecule 758 0.342 0.862 0.300 1 0 2005 2005
Entrez Id: 3357
Gene Symbol: HTR2B
HTR2B
P41595 5-hydroxytryptamine receptor 2B receptor 34 0.696 0.310 3.5E-10 0.300 1 0 2004 2004
Entrez Id: 5592
Gene Symbol: PRKG1
PRKG1
Q13976 protein kinase cGMP-dependent 1 94 0.575 0.724 1.00 0.300 1 0 2011 2011
Entrez Id: 2658
Gene Symbol: GDF2
GDF2
Q9UK05 growth differentiation factor 2 signaling molecule 43 0.656 0.448 2.5E-03 0.300 1 0 2016 2016