Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5896
Gene Symbol: RAG1
RAG1
P15918 recombination activating 1 Enzyme 209 0.509 0.769 2.8E-05 0.200 None 0.947 19 1 1999 2019
Entrez Id: 959
Gene Symbol: CD40LG
CD40LG
P29965 CD40 ligand Signaling 453 0.414 0.846 0.72 0.170 None 1.000 7 0 1999 2018
Entrez Id: 930
Gene Symbol: CD19
CD19
P15391 CD19 molecule 365 0.430 0.885 0.90 0.170 None 1.000 7 0 1992 2013
Entrez Id: 7015
Gene Symbol: TERT
TERT
O14746 telomerase reverse transcriptase Enzyme 703 0.374 0.846 0.99 0.170 None 0.857 7 0 2003 2018
Entrez Id: 2624
Gene Symbol: GATA2
GATA2
P23769 GATA binding protein 2 229 0.496 0.654 0.98 0.160 None 0.833 6 0 2012 2018
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.160 None 1.000 6 0 2009 2018
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4
P16410 cytotoxic T-lymphocyte associated protein 4 722 0.369 0.923 0.94 0.150 None 1.000 5 0 2004 2019
Entrez Id: 695
Gene Symbol: BTK
BTK
Q06187 Bruton tyrosine kinase Kinase 290 0.464 0.808 1.00 0.150 None 1.000 5 2 1994 2017
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 821 0.344 0.923 1.00 0.150 None 1.000 5 0 1989 2019
Entrez Id: 6772
Gene Symbol: STAT1
STAT1
P42224 signal transducer and activator of transcription 1 Nucleic acid binding 531 0.399 0.885 1.00 0.150 None 1.000 5 0 2001 2018
Entrez Id: 987
Gene Symbol: LRBA
LRBA
P50851 LPS responsive beige-like anchor protein 71 0.608 0.692 7.2E-12 0.150 None 1.000 5 0 2015 2019
Entrez Id: 940
Gene Symbol: CD28
CD28
P10747 CD28 molecule 364 0.436 0.885 0.36 0.150 None 1.000 5 0 1997 2004
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.150 None 1.000 5 0 1996 2019
Entrez Id: 7454
Gene Symbol: WAS
WAS
P42768 WASP actin nucleation promoting factor Cellular structure 204 0.529 0.808 1.00 0.140 None 1.000 4 0 2005 2018
Entrez Id: 857
Gene Symbol: CAV1
CAV1
Q03135 caveolin 1 Enzyme modulator 633 0.388 0.885 8.3E-03 0.140 None 1.000 4 0 2017 2019
Entrez Id: 331
Gene Symbol: XIAP
XIAP
P98170 X-linked inhibitor of apoptosis Enzyme modulator 321 0.447 0.808 0.92 0.140 None 1.000 4 0 2005 2019
Entrez Id: 1536
Gene Symbol: CYBB
CYBB
P04839 cytochrome b-245 beta chain Ion channel 343 0.452 0.885 1.00 0.140 None 1.000 4 0 2017 2019
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.140 None 1.000 4 0 1990 2018
Entrez Id: 59067
Gene Symbol: IL21
IL21
Q9HBE4 interleukin 21 321 0.441 0.769 0.63 0.130 None 1.000 3 0 2013 2018
Entrez Id: 931
Gene Symbol: MS4A1
MS4A1
P11836 membrane spanning 4-domains A1 Receptor 451 0.411 0.846 5.1E-05 0.130 None 1.000 3 0 2005 2018
Entrez Id: 84876
Gene Symbol: ORAI1
ORAI1
Q96D31 ORAI calcium release-activated calcium modulator 1 Ion channel 195 0.520 0.808 1.9E-05 0.130 None 1.000 3 0 2006 2019
Entrez Id: 60
Gene Symbol: ACTB
ACTB
P60709 actin beta Cellular structure 1110 0.325 0.923 0.99 0.130 None 1.000 3 0 2016 2020
Entrez Id: 4068
Gene Symbol: SH2D1A
SH2D1A
O60880 SH2 domain containing 1A 160 0.525 0.731 0.39 0.130 None 1.000 3 0 2003 2017
Entrez Id: 958
Gene Symbol: CD40
CD40
P25942 CD40 molecule 528 0.396 0.846 0.85 0.120 None 1.000 2 0 2005 2019
Entrez Id: 5873
Gene Symbol: RAB27A
RAB27A
P51159 RAB27A, member RAS oncogene family 108 0.585 0.692 3.0E-07 0.120 None 1.000 2 0 2003 2013