Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3586
Gene Symbol: IL10
IL10
P22301 interleukin 10 961 0.320 0.931 6.5E-03 0.700 0.987 79 4 1995 2018
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor signaling molecule 1640 0.263 0.966 0.80 0.600 0.963 110 0 1992 2018
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
Q9HC29 nucleotide binding oligomerization domain containing 2 hydrolase; nucleic acid binding; protease; transcription factor 265 0.458 0.862 1.6E-30 0.500 0.901 152 12 1998 2018
Entrez Id: 149233
Gene Symbol: IL23R
IL23R
Q5VWK5 interleukin 23 receptor defense/immunity protein; signaling molecule 170 0.505 0.724 7.0E-04 0.500 0.917 65 6 2006 2017
Entrez Id: 55054
Gene Symbol: ATG16L1
ATG16L1
Q676U5 autophagy related 16 like 1 66 0.586 0.586 0.94 0.500 0.957 26 3 2007 2017
Entrez Id: 9966
Gene Symbol: TNFSF15
TNFSF15
O95150 TNF superfamily member 15 signaling molecule 82 0.584 0.621 3.0E-03 0.500 1.000 17 4 2004 2017
Entrez Id: 345611
Gene Symbol: IRGM
IRGM
A1A4Y4 immunity related GTPase M 35 0.648 0.345 0.500 1.000 14 2 2009 2017
Entrez Id: 64170
Gene Symbol: CARD9
CARD9
Q9H257 caspase recruitment domain family member 9 52 0.624 0.448 9.8E-12 0.460 0.833 10 3 2008 2018
Entrez Id: 8807
Gene Symbol: IL18RAP
IL18RAP
O95256 interleukin 18 receptor accessory protein receptor 22 0.720 0.517 2.0E-03 0.410 1.000 3 2 2008 2016
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 1330 0.287 0.966 0.34 0.400 0.931 29 0 1992 2018
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 nucleic acid binding; transcription factor 706 0.358 0.862 1.00 0.400 1.000 20 2 2006 2018
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 oxidoreductase 832 0.338 0.897 1.00 0.400 1.000 12 0 1998 2015
Entrez Id: 283463
Gene Symbol: MUC19
MUC19
Q7Z5P9 mucin 19, oligomeric 8 0.799 0.310 8.9E-30 0.400 2 1 2011 2012
Entrez Id: 5336
Gene Symbol: PLCG2
PLCG2
P16885 phospholipase C gamma 2 calcium-binding protein; enzyme modulator; hydrolase; signaling molecule 50 0.636 0.621 1.00 0.400 1 1 2017 2017
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
P05362 intercellular adhesion molecule 1 489 0.386 0.897 3.8E-02 0.380 1.000 9 2 1995 2017
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Q9Y2R2 protein tyrosine phosphatase, non-receptor type 22 210 0.497 0.793 3.6E-19 0.360 0.667 7 1 2005 2014
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC, WNT signaling pathway regulator 462 0.397 0.828 1.00 0.360 0.667 7 1 1998 2016
Entrez Id: 6556
Gene Symbol: SLC11A1
SLC11A1
P49279 solute carrier family 11 member 1 transporter 107 0.537 0.793 3.5E-19 0.350 1.000 6 0 1999 2011
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
P01589 interleukin 2 receptor subunit alpha receptor 361 0.419 0.828 5.2E-02 0.340 1.000 6 1 2004 2016
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 signaling molecule 847 0.336 0.931 0.17 0.330 1.000 4 1 2013 2018
Entrez Id: 1670
Gene Symbol: DEFA5
DEFA5
Q01523 defensin alpha 5 19 0.743 0.345 5.9E-06 0.320 1.000 2 0 2008 2017
Entrez Id: 8876
Gene Symbol: VNN1
VNN1
O95497 vanin 1 hydrolase 20 0.727 0.310 3.1E-06 0.310 1.000 2 0 2007 2014
Entrez Id: 55765
Gene Symbol: INAVA
INAVA
Q3KP66 innate immunity activator 1 0.310 1.000 2 2 2011 2017
Entrez Id: 3676
Gene Symbol: ITGA4
ITGA4
P13612 integrin subunit alpha 4 73 0.596 0.655 8.8E-05 0.310 1.000 2 0 2016 2017
Entrez Id: 10297
Gene Symbol: APC2
APC2
O95996 APC2, WNT signaling pathway regulator 82 0.633 0.552 1.00 0.310 1.000 1 0 2009 2009