Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4297
Gene Symbol: KMT2A
KMT2A
Q03164 lysine methyltransferase 2A 311 0.460 0.793 1.00 0.300 0.968 158 1 1993 2018
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog hydrolase; phosphatase 915 0.334 0.828 0.82 0.260 1.000 6 0 2003 2017
Entrez Id: 4005
Gene Symbol: LMO2
LMO2
P25791 LIM domain only 2 44 0.639 0.414 0.17 0.240 1.000 4 0 1994 2011
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit 425 0.421 0.759 1.00 0.220 1.000 2 0 2016 2017
Entrez Id: 2120
Gene Symbol: ETV6
ETV6
P41212 ETS variant 6 nucleic acid binding; signaling molecule; transcription factor 157 0.509 0.655 0.99 0.200 0.971 140 3 1995 2018
Entrez Id: 613
Gene Symbol: BCR
BCR
P11274 BCR, RhoGEF and GTPase activating protein enzyme modulator 244 0.470 0.759 1.00 0.200 0.940 100 0 1981 2018
Entrez Id: 2322
Gene Symbol: FLT3
FLT3
P36888 fms related tyrosine kinase 3 168 0.503 0.517 0.61 0.200 1.000 42 3 1996 2018
Entrez Id: 6886
Gene Symbol: TAL1
TAL1
P17542 TAL bHLH transcription factor 1, erythroid differentiation factor nucleic acid binding; transcription factor 85 0.572 0.483 0.58 0.200 1.000 11 0 1993 2016
Entrez Id: 4854
Gene Symbol: NOTCH3
NOTCH3
Q9UM47 notch 3 312 0.469 0.690 0.87 0.200 0 0
Entrez Id: 4683
Gene Symbol: NBN
NBN
O60934 nibrin nucleic acid binding 214 0.502 0.759 2.6E-16 0.140 1.000 5 7 2004 2015
Entrez Id: 9487
Gene Symbol: PIGL
PIGL
Q9Y2B2 phosphatidylinositol glycan anchor biosynthesis class L 98 0.636 0.621 6.9E-09 0.110 1.000 1 0 1997 1997
Entrez Id: 25
Gene Symbol: ABL1
ABL1
P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase 233 0.475 0.690 1.00 0.100 0.964 193 3 1987 2018
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1
Q01196 runt related transcription factor 1 nucleic acid binding; transcription factor 248 0.467 0.690 0.88 0.100 0.987 150 0 1995 2017
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 891 0.321 0.828 0.38 0.100 0.969 65 2 1994 2018
Entrez Id: 923
Gene Symbol: CD6
CD6
P30203 CD6 molecule hydrolase; oxidoreductase; protease; receptor 107 0.540 0.586 5.0E-04 0.100 0.966 59 0 1994 2016
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
T cell receptor beta variable 20/OR9-2 (non-functional) 319 0.423 0.897 0.100 0.982 55 0 1987 2016
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.100 0.941 51 1 1986 2017
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1
Q13422 IKAROS family zinc finger 1 transcription factor 102 0.575 0.621 1.00 0.100 1.000 50 1 2000 2018
Entrez Id: 5087
Gene Symbol: PBX1
PBX1
P40424 PBX homeobox 1 nucleic acid binding; transcription factor 89 0.577 0.655 1.00 0.100 0.938 48 0 1991 2017
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 699 0.354 0.828 1.2E-09 0.100 0.927 41 4 1999 2018
Entrez Id: 4311
Gene Symbol: MME
MME
P08473 membrane metalloendopeptidase hydrolase; protease 237 0.461 0.690 7.0E-17 0.100 0.951 41 0 1985 2013
Entrez Id: 930
Gene Symbol: CD19
CD19
P15391 CD19 molecule 214 0.483 0.724 0.89 0.100 0.972 36 0 1987 2017
Entrez Id: 7172
Gene Symbol: TPMT
TPMT
P51580 thiopurine S-methyltransferase 50 0.636 0.483 9.5E-06 0.100 0.943 35 2 1987 2016
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
P08183 ATP binding cassette subfamily B member 1 hydrolase; protease 606 0.371 0.828 1.3E-05 0.100 0.886 35 2 1989 2015
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2, apoptosis regulator signaling molecule 987 0.312 0.862 0.57 0.100 0.971 34 0 1995 2016