Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.400 limited 0.988 83 3 1994 2019
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1
Q13422 IKAROS family zinc finger 1 Transcription factor 165 0.533 0.769 1.00 0.400 moderate 1.000 81 4 1999 2019
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch receptor 1 693 0.369 0.885 1.00 0.400 limited 1.000 20 0 2005 2019
Entrez Id: 10019
Gene Symbol: SH2B3
SH2B3
Q9UQQ2 SH2B adaptor protein 3 212 0.527 0.692 1.0E-04 0.330 moderate 1.000 3 0 2013 2018
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
Q969H0 F-box and WD repeat domain containing 7 Enzyme modulator 257 0.465 0.808 1.00 0.330 limited 1.000 3 0 2008 2016
Entrez Id: 4297
Gene Symbol: KMT2A
KMT2A
Q03164 lysine methyltransferase 2A 535 0.410 0.885 1.00 0.300 None 0.970 203 1 1993 2020
Entrez Id: 3981
Gene Symbol: LIG4
LIG4
P49917 DNA ligase 4 293 0.478 0.846 4.2E-06 0.300 strong 1.000 1 0 2017 2017
Entrez Id: 641
Gene Symbol: BLM
BLM
P54132 BLM RecQ like helicase 158 0.535 0.808 1.5E-15 0.300 strong 1.000 1 0 2017 2017
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.270 None 1.000 7 0 2003 2019
Entrez Id: 4005
Gene Symbol: LMO2
LMO2
P25791 LIM domain only 2 83 0.585 0.654 0.16 0.250 None 1.000 5 0 1993 2019
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 653 0.376 0.885 1.00 0.220 None 1.000 2 0 2016 2016
Entrez Id: 4854
Gene Symbol: NOTCH3
NOTCH3
Q9UM47 notch receptor 3 418 0.435 0.808 0.41 0.210 None 1.000 1 0 2019 2019
Entrez Id: 2120
Gene Symbol: ETV6
ETV6
P41212 ETS variant transcription factor 6 Transcription factor 241 0.477 0.731 0.97 0.200 None 0.985 197 4 1995 2020
Entrez Id: 2322
Gene Symbol: FLT3
FLT3
P36888 fms related receptor tyrosine kinase 3 Kinase 270 0.462 0.654 0.61 0.200 None 0.979 48 3 1996 2020
Entrez Id: 4683
Gene Symbol: NBN
NBN
O60934 nibrin Nucleic acid binding 291 0.467 0.808 2.2E-16 0.140 None 1.000 4 8 2004 2014
Entrez Id: 25
Gene Symbol: ABL1
ABL1
P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 395 0.432 0.923 1.00 0.100 None 0.970 264 5 1987 2020
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1
Q01196 RUNX family transcription factor 1 Transcription factor 412 0.425 0.808 0.65 0.100 None 0.976 209 0 1995 2020
Entrez Id: 613
Gene Symbol: BCR
BCR
P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 392 0.431 0.885 0.99 0.100 None 0.956 135 0 1981 2020
Entrez Id: 930
Gene Symbol: CD19
CD19
P15391 CD19 molecule 365 0.430 0.885 0.90 0.100 None 0.970 101 0 1987 2020
Entrez Id: 374569
Gene Symbol: ASPG
ASPG
Q86U10 asparaginase 116 0.559 0.654 6.2E-13 0.100 None 0.988 80 0 1994 2020
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.100 None 0.946 74 7 1999 2019
Entrez Id: 80150
Gene Symbol: ASRGL1
ASRGL1
Q7L266 asparaginase and isoaspartyl peptidase 1 Enzyme 205 0.494 0.808 2.8E-05 0.100 None 0.986 73 0 1983 2020
Entrez Id: 923
Gene Symbol: CD6
CD6
P30203 CD6 molecule Enzyme 216 0.489 0.808 9.3E-05 0.100 None 0.972 72 0 1994 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.100 None 0.956 68 3 1986 2020
Entrez Id: 5087
Gene Symbol: PBX1
PBX1
P40424 PBX homeobox 1 Transcription factor 167 0.534 0.846 1.00 0.100 None 0.955 67 0 1991 2019