Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.400 0.940 87 1 1991 2017
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor signaling molecule 1640 0.263 0.966 0.80 0.400 0.957 48 0 1989 2016
Entrez Id: 196
Gene Symbol: AHR
AHR
P35869 aryl hydrocarbon receptor receptor; transcription factor 276 0.462 0.862 1.00 0.400 0.920 26 1 1990 2018
Entrez Id: 3082
Gene Symbol: HGF
HGF
P14210 hepatocyte growth factor hydrolase; protease 478 0.394 0.793 1.00 0.400 1.000 23 0 1992 2014
Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10
P50591 TNF superfamily member 10 signaling molecule 295 0.440 0.828 0.13 0.400 0.950 21 0 2003 2015
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor nucleic acid binding; transcription factor 499 0.382 0.724 1.00 0.400 1.000 18 0 1985 2015
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 nucleic acid binding; transcription factor 706 0.358 0.862 1.00 0.400 1.000 17 0 1994 2016
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 enzyme modulator 589 0.365 0.828 0.90 0.400 0.929 15 0 2001 2016
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 891 0.321 0.828 0.38 0.400 0.909 14 0 2000 2016
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
P05181 cytochrome P450 family 2 subfamily E member 1 212 0.473 0.759 3.9E-07 0.400 1.000 13 0 1997 2017
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
P05121 serpin family E member 1 enzyme modulator 506 0.384 0.793 4.7E-02 0.400 0.917 13 0 1991 2011
Entrez Id: 3481
Gene Symbol: IGF2
IGF2
P01344 insulin like growth factor 2 505 0.399 0.828 4.7E-02 0.400 0.800 11 0 1990 2005
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase enzyme modulator 545 0.404 0.828 8.7E-02 0.390 0.889 13 0 1987 2009
Entrez Id: 3558
Gene Symbol: IL2
IL2
P60568 interleukin 2 564 0.373 0.931 0.49 0.390 1.000 10 0 1994 2017
Entrez Id: 5465
Gene Symbol: PPARA
PPARA
Q07869 peroxisome proliferator activated receptor alpha nucleic acid binding; receptor; transcription factor 247 0.465 0.793 3.7E-02 0.390 1.000 10 0 2002 2015
Entrez Id: 9971
Gene Symbol: NR1H4
NR1H4
Q96RI1 nuclear receptor subfamily 1 group H member 4 nucleic acid binding; receptor; transcription factor 149 0.522 0.655 1.3E-03 0.380 1.000 12 0 2003 2017
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 nucleic acid binding; receptor; transcription factor 686 0.355 0.897 1.00 0.380 1.000 9 0 1996 2016
Entrez Id: 2705
Gene Symbol: GJB1
GJB1
P08034 gap junction protein beta 1 cell junction protein 165 0.527 0.621 0.84 0.380 0.875 9 0 1990 2016
Entrez Id: 7015
Gene Symbol: TERT
TERT
O14746 telomerase reverse transcriptase nucleic acid binding 541 0.393 0.828 1.00 0.380 1.000 9 0 2002 2016
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 412 0.417 0.759 1.00 0.370 1.000 9 0 1998 2014
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
P09601 heme oxygenase 1 oxidoreductase 460 0.403 0.862 7.9E-03 0.370 1.000 8 0 2003 2009
Entrez Id: 3439
Gene Symbol: IFNA1
IFNA1
P01562 interferon alpha 1 405 0.403 0.828 0.370 1.000 8 0 2004 2013
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
P04141 colony stimulating factor 2 signaling molecule 670 0.356 0.966 0.84 0.370 1.000 7 0 2001 2012
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
P46527 cyclin dependent kinase inhibitor 1B 334 0.424 0.724 0.66 0.360 1.000 7 0 1998 2006
Entrez Id: 540
Gene Symbol: ATP7B
ATP7B
P35670 ATPase copper transporting beta hydrolase; transporter 166 0.547 0.621 5.4E-30 0.350 0.800 6 1 2000 2015