Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.320 None 1.000 3 0 2006 2016
Entrez Id: 10411
Gene Symbol: RAPGEF3
RAPGEF3
O95398 Rap guanine nucleotide exchange factor 3 Enzyme modulator 99 0.593 0.692 7.1E-23 0.320 None 1.000 2 0 2012 2019
Entrez Id: 2920
Gene Symbol: CXCL2
CXCL2
P19875 C-X-C motif chemokine ligand 2 Signaling 186 0.513 0.885 3.6E-07 0.310 None 1.000 2 0 2013 2016
Entrez Id: 4323
Gene Symbol: MMP14
MMP14
P50281 matrix metallopeptidase 14 Enzyme 340 0.447 0.769 1.00 0.310 None 1.000 2 0 2006 2009
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2
P45379 troponin T2, cardiac type Cellular structure 79 0.601 0.423 2.0E-03 0.310 None 1.000 2 0 2007 2008
Entrez Id: 688
Gene Symbol: KLF5
KLF5
Q13887 Kruppel like factor 5 Nucleic acid binding 143 0.534 0.769 0.82 0.310 None 1.000 1 0 2019 2019
Entrez Id: 925
Gene Symbol: CD8A
CD8A
P01732 CD8a molecule 87 0.587 0.769 1.7E-05 0.310 None 1.000 1 0 2007 2007
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Q16236 nuclear factor, erythroid 2 like 2 Enzyme 823 0.357 0.885 3.6E-03 0.300 None 0.972 36 2 2008 2019
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
Q16552 interleukin 17A 1074 0.324 0.923 4.3E-02 0.300 None 0.963 27 2 2004 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.300 None 0.963 27 0 2003 2019
Entrez Id: 4586
Gene Symbol: MUC5AC
MUC5AC
P98088 mucin 5AC, oligomeric mucus/gel-forming Enzyme modulator 224 0.483 0.808 1.0E-08 0.300 None 1.000 17 0 2004 2020
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 603 0.380 0.885 0.50 0.300 None 1.000 13 1 2001 2019
Entrez Id: 407001
Gene Symbol: MIR218-2
MIR218-2
microRNA 218-2 19 0.716 0.385 0.300 None 1.000 1 0 2017 2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.280 None 0.889 9 0 2012 2019
Entrez Id: 836
Gene Symbol: CASP3
CASP3
P42574 caspase 3 Enzyme 819 0.351 0.923 0.10 0.250 None 1.000 6 0 2009 2019
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
P05121 serpin family E member 1 Enzyme modulator 770 0.359 0.885 4.4E-02 0.240 None 1.000 5 0 2007 2017
Entrez Id: 4582
Gene Symbol: MUC1
MUC1
P15941 mucin 1, cell surface associated 594 0.384 0.885 1.9E-02 0.230 None 1.000 4 0 2011 2019
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
P00749 plasminogen activator, urokinase Enzyme 439 0.425 0.923 2.3E-06 0.230 None 1.000 4 0 2005 2019
Entrez Id: 6590
Gene Symbol: SLPI
SLPI
P03973 secretory leukocyte peptidase inhibitor Enzyme modulator 310 0.449 0.846 9.0E-04 0.230 None 1.000 4 0 2000 2020
Entrez Id: 1490
Gene Symbol: CCN2
CCN2
P29279 cellular communication network factor 2 Signaling 518 0.399 0.846 5.0E-04 0.220 None 1.000 3 0 2009 2015
Entrez Id: 4353
Gene Symbol: MPO
MPO
P05164 myeloperoxidase Enzyme 653 0.377 0.923 7.1E-15 0.220 None 1.000 3 0 2007 2017
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
Q14765 signal transducer and activator of transcription 4 Nucleic acid binding 316 0.471 0.769 0.77 0.220 None 1.000 3 0 2013 2019
Entrez Id: 1649
Gene Symbol: DDIT3
DDIT3
P35638 DNA damage inducible transcript 3 264 0.467 0.846 0.59 0.210 None 1.000 2 0 2008 2014
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
Q13485 SMAD family member 4 Transcription factor 575 0.401 0.808 1.00 0.210 None 1.000 2 0 2008 2018
Entrez Id: 664
Gene Symbol: BNIP3
BNIP3
Q12983 BCL2 interacting protein 3 158 0.520 0.731 2.0E-05 0.210 None 1.000 2 0 2015 2018