Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 472
Gene Symbol: ATM
ATM
Q13315 ATM serine/threonine kinase kinase; nucleic acid binding; transferase 486 0.401 0.862 6.0E-46 0.600 0.905 23 0 1998 2017
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2, apoptosis regulator signaling molecule 987 0.312 0.862 0.57 0.500 0.949 283 0 1987 2018
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit 425 0.421 0.759 1.00 0.500 1.000 33 3 2001 2018
Entrez Id: 4615
Gene Symbol: MYD88
MYD88
Q99836 myeloid differentiation primary response 88 234 0.470 0.828 0.14 0.500 1.000 18 1 2011 2017
Entrez Id: 5551
Gene Symbol: PRF1
PRF1
P14222 perforin 1 225 0.475 0.690 4.4E-06 0.490 0.889 9 0 1995 2016
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
P40692 mutL homolog 1 nucleic acid binding 356 0.424 0.759 5.1E-05 0.470 0.833 8 0 1997 2005
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
P01111 NRAS proto-oncogene, GTPase enzyme modulator 477 0.420 0.690 0.53 0.430 0.667 4 1 1993 2013
Entrez Id: 641
Gene Symbol: BLM
BLM
P54132 Bloom syndrome RecQ like helicase 137 0.562 0.690 9.3E-15 0.410 1.000 1 0 2002 2002
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.400 0.948 177 8 1986 2018
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 891 0.321 0.828 0.38 0.400 0.911 49 0 1995 2016
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch 1 389 0.415 0.759 1.00 0.400 1.000 20 0 1999 2015
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog hydrolase; phosphatase 915 0.334 0.828 0.82 0.400 0.923 15 0 1998 2018
Entrez Id: 1030
Gene Symbol: CDKN2B
CDKN2B
P42772 cyclin dependent kinase inhibitor 2B 300 0.438 0.759 8.2E-03 0.390 1.000 10 0 1995 2011
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 699 0.354 0.828 1.2E-09 0.390 1.000 10 1 2004 2016
Entrez Id: 1019
Gene Symbol: CDK4
CDK4
P11802 cyclin dependent kinase 4 kinase; transferase 266 0.449 0.724 7.8E-02 0.380 1.000 8 1 2000 2017
Entrez Id: 29126
Gene Symbol: CD274
CD274
Q9NZQ7 CD274 molecule defense/immunity protein; receptor; signaling molecule 257 0.458 0.828 2.2E-02 0.360 1.000 7 0 2011 2018
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3
P21580 TNF alpha induced protein 3 hydrolase; nucleic acid binding; protease 104 0.538 0.621 1.00 0.360 1.000 6 1 2009 2016
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1
Q13422 IKAROS family zinc finger 1 transcription factor 102 0.575 0.621 1.00 0.340 1.000 5 0 2000 2008
Entrez Id: 64919
Gene Symbol: BCL11B
BCL11B
Q9C0K0 B cell CLL/lymphoma 11B transcription factor 72 0.624 0.483 0.99 0.340 0.750 5 0 2003 2015
Entrez Id: 387
Gene Symbol: RHOA
RHOA
P61586 ras homolog family member A enzyme modulator 96 0.565 0.586 0.86 0.340 1.000 4 0 2014 2016
Entrez Id: 8651
Gene Symbol: SOCS1
SOCS1
O15524 suppressor of cytokine signaling 1 enzyme modulator 188 0.483 0.759 0.58 0.340 0.667 4 0 2003 2013
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase enzyme modulator 886 0.350 0.724 9.0E-04 0.330 1.000 4 1 1997 2013
Entrez Id: 3718
Gene Symbol: JAK3
JAK3
P52333 Janus kinase 3 123 0.532 0.621 3.3E-05 0.330 0.667 3 0 2002 2014
Entrez Id: 4853
Gene Symbol: NOTCH2
NOTCH2
Q04721 notch 2 287 0.474 0.724 1.00 0.330 1.000 3 0 2005 2015
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
P07099 epoxide hydrolase 1 hydrolase; protease 150 0.510 0.759 3.7E-09 0.320 1.000 3 0 2001 2014