Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 472
Gene Symbol: ATM
ATM 		Q13315 ATM serine/threonine kinase Kinase 684 0.374 0.885 5.6E-47 0.900 strong 0.955 22 0 1998 2020
Entrez Id: 5551
Gene Symbol: PRF1
PRF1 		P14222 perforin 1 163 0.540 0.692 5.5E-06 0.620 strong 1.000 2 0 2008 2015
Entrez Id: 641
Gene Symbol: BLM
BLM 		P54132 BLM RecQ like helicase 158 0.535 0.808 1.5E-15 0.610 strong 1.000 2 0 2002 2017
Entrez Id: 7454
Gene Symbol: WAS
WAS 		P42768 WASP actin nucleation promoting factor Cellular structure 204 0.529 0.808 1.00 0.610 strong 1.000 2 0 2017 2019
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.500 None 0.981 262 0 1987 2020
Entrez Id: 2146
Gene Symbol: EZH2
EZH2 		Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 653 0.376 0.885 1.00 0.500 None 1.000 44 3 2003 2020
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.500 None 0.951 41 0 1995 2019
Entrez Id: 4615
Gene Symbol: MYD88
MYD88 		Q99836 MYD88 innate immune signal transduction adaptor Enzyme modulator 480 0.414 0.923 0.12 0.500 None 1.000 26 1 2011 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.500 None 0.923 13 1 1998 2018
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		P40692 mutL homolog 1 Nucleic acid binding 526 0.399 0.808 3.4E-05 0.490 None 1.000 10 0 1997 2019
Entrez Id: 4068
Gene Symbol: SH2D1A
SH2D1A 		O60880 SH2 domain containing 1A 160 0.525 0.731 0.39 0.470 strong 0.857 7 0 1998 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.440 None 1.000 5 1 1997 2013
Entrez Id: 3981
Gene Symbol: LIG4
LIG4 		P49917 DNA ligase 4 293 0.478 0.846 4.2E-06 0.420 strong 1.000 3 0 2002 2017
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		P01111 NRAS proto-oncogene, GTPase Enzyme modulator 611 0.390 0.808 0.49 0.410 None 1.000 2 1 1993 1997
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.400 None 0.955 156 9 1986 2019
Entrez Id: 29126
Gene Symbol: CD274
CD274 		Q9NZQ7 CD274 molecule Receptor 1011 0.324 0.923 1.9E-02 0.400 None 0.966 29 0 2011 2019
Entrez Id: 355
Gene Symbol: FAS
FAS 		P25445 Fas cell surface death receptor 754 0.372 0.923 0.81 0.400 strong 1.000 16 0 1995 2016
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1 		P46531 notch receptor 1 693 0.369 0.885 1.00 0.400 None 1.000 15 0 1998 2019
Entrez Id: 1030
Gene Symbol: CDKN2B
CDKN2B 		P42772 cyclin dependent kinase inhibitor 2B 440 0.417 0.769 7.3E-03 0.400 None 1.000 12 0 1995 2011
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.390 None 1.000 10 2 2004 2016
Entrez Id: 1019
Gene Symbol: CDK4
CDK4 		P11802 cyclin dependent kinase 4 Kinase 433 0.412 0.808 6.3E-02 0.390 None 1.000 9 1 1996 2018
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.370 limited 0.857 7 2 2012 2018
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3 		P21580 TNF alpha induced protein 3 Enzyme 212 0.481 0.808 1.00 0.360 None 1.000 6 1 2009 2016
Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1 		Q13422 IKAROS family zinc finger 1 Transcription factor 165 0.533 0.769 1.00 0.340 None 1.000 5 0 1999 2008
Entrez Id: 3718
Gene Symbol: JAK3
JAK3 		P52333 Janus kinase 3 Kinase 194 0.505 0.731 5.9E-06 0.340 None 1.000 4 0 2010 2018