Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 999
Gene Symbol: CDH1
CDH1
P12830 cadherin 1 322 0.432 0.759 0.11 0.700 0.947 117 4 1997 2018
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase 407 0.405 0.793 0.99 0.700 1.000 52 3 1997 2018
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 650 0.352 0.862 1.8E-03 0.600 0.977 224 1 1986 2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha kinase; transferase 835 0.341 0.897 1.00 0.600 1.000 56 0 2005 2018
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 891 0.321 0.828 0.38 0.600 0.968 33 0 1995 2017
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
P21802 fibroblast growth factor receptor 2 665 0.398 0.759 1.00 0.600 1.000 29 1 1995 2018
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC, WNT signaling pathway regulator 462 0.397 0.828 1.00 0.600 0.900 20 0 1992 2017
Entrez Id: 472
Gene Symbol: ATM
ATM
Q13315 ATM serine/threonine kinase kinase; nucleic acid binding; transferase 486 0.401 0.862 6.0E-46 0.600 1.000 15 0 1998 2018
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
O15392 baculoviral IAP repeat containing 5 enzyme modulator 191 0.479 0.655 5.7E-02 0.590 1.000 11 0 2002 2017
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
P38936 cyclin dependent kinase inhibitor 1A 369 0.415 0.724 2.1E-03 0.590 1.000 11 1 1998 2016
Entrez Id: 3659
Gene Symbol: IRF1
IRF1
P10914 interferon regulatory factor 1 nucleic acid binding; transcription factor 165 0.503 0.724 0.99 0.550 1.000 5 1 1998 2017
Entrez Id: 1316
Gene Symbol: KLF6
KLF6
Q99612 Kruppel like factor 6 nucleic acid binding; transcription factor 125 0.534 0.690 0.98 0.540 1.000 4 1 2005 2012
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Q9UIF7 mutY DNA glycosylase hydrolase; nucleic acid binding 99 0.551 0.621 2.7E-17 0.540 1.000 4 2 2004 2011
Entrez Id: 843
Gene Symbol: CASP10
CASP10
Q92851 caspase 10 enzyme modulator; hydrolase; protease 102 0.561 0.517 5.2E-12 0.520 1.000 2 0 2002 2004
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.400 0.919 163 2 1991 2018
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 oxidoreductase 832 0.338 0.897 1.00 0.400 0.988 86 7 1999 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor 892 0.325 0.862 0.50 0.400 1.000 76 1 1995 2018
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1035 0.312 0.931 0.13 0.400 0.928 71 1 2000 2017
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor signaling molecule 1640 0.263 0.966 0.80 0.400 0.966 60 2 1992 2018
Entrez Id: 864
Gene Symbol: RUNX3
RUNX3
Q13761 runt related transcription factor 3 nucleic acid binding; transcription factor 168 0.494 0.690 0.96 0.400 0.962 54 4 2002 2017
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
P10145 C-X-C motif chemokine ligand 8 signaling molecule 758 0.342 0.862 0.400 1.000 45 2 1992 2017
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
P40692 mutL homolog 1 nucleic acid binding 356 0.424 0.759 5.1E-05 0.400 0.921 39 3 1997 2018
Entrez Id: 960
Gene Symbol: CD44
CD44
P16070 CD44 molecule (Indian blood group) 467 0.389 0.862 2.1E-07 0.400 0.973 37 1 1993 2018
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 nucleic acid binding; transcription factor 706 0.358 0.862 1.00 0.400 1.000 36 1 2004 2018
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
P04818 thymidylate synthetase transferase 256 0.457 0.759 0.76 0.400 1.000 34 1 1993 2016