Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.400 None 0.914 105 5 1995 2019
Entrez Id: 4548
Gene Symbol: MTR
MTR 		Q99707 5-methyltetrahydrofolate-homocysteine methyltransferase 245 0.482 0.808 2.4E-12 0.100 None 0.810 21 5 1996 2019
Entrez Id: 5077
Gene Symbol: PAX3
PAX3 		P23760 paired box 3 257 0.481 0.769 0.24 0.400 None 0.905 21 0 1988 2019
Entrez Id: 4552
Gene Symbol: MTRR
MTRR 		Q9UBK8 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 207 0.502 0.808 2.2E-14 0.100 None 1.000 18 3 2003 2019
Entrez Id: 4522
Gene Symbol: MTHFD1
MTHFD1 		P11586 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Enzyme 121 0.554 0.769 4.5E-03 0.400 None 0.941 17 6 1998 2019
Entrez Id: 57216
Gene Symbol: VANGL2
VANGL2 		Q9ULK5 VANGL planar cell polarity protein 2 78 0.588 0.615 0.84 0.600 None 1.000 12 2 1990 2015
Entrez Id: 174
Gene Symbol: AFP
AFP 		P02771 alpha fetoprotein Transporter 392 0.429 0.885 1.1E-11 0.100 None 0.909 11 0 1975 2018
Entrez Id: 2348
Gene Symbol: FOLR1
FOLR1 		P15328 folate receptor alpha 174 0.522 0.885 0.13 0.400 None 1.000 11 1 1998 2019
Entrez Id: 649
Gene Symbol: BMP1
BMP1 		P13497 bone morphogenetic protein 1 121 0.554 0.769 8.9E-04 0.100 None 1.000 10 0 2009 2019
Entrez Id: 5981
Gene Symbol: RFC1
RFC1 		P35251 replication factor C subunit 1 144 0.541 0.808 0.97 0.100 None 0.800 10 0 2001 2019
Entrez Id: 54858
Gene Symbol: PGPEP1
PGPEP1 		Q9NXJ5 pyroglutamyl-peptidase I Enzyme 116 0.581 0.769 8.5E-03 0.100 None 1.000 10 0 2009 2019
Entrez Id: 5547
Gene Symbol: PRCP
PRCP 		P42785 prolylcarboxypeptidase Enzyme 68 0.633 0.692 8.8E-12 0.100 None 1.000 10 2 2009 2019
Entrez Id: 102724560
Gene Symbol: CBSL
CBSL 		P0DN79 P35520 cystathionine beta-synthase like 129 0.540 0.808 0.090 None 0.889 9 0 1996 2014
Entrez Id: 875
Gene Symbol: CBS
CBS 		P0DN79 P35520 cystathionine beta-synthase Enzyme 295 0.465 0.885 3.1E-05 0.090 None 0.778 9 2 1996 2014
Entrez Id: 6573
Gene Symbol: SLC19A1
SLC19A1 		P41440 solute carrier family 19 member 1 Transporter 155 0.523 0.692 6.5E-06 0.090 None 0.778 9 4 2001 2017
Entrez Id: 80199
Gene Symbol: FUZ
FUZ 		Q9BT04 fuzzy planar cell polarity protein 75 0.597 0.731 1.3E-05 0.590 None 0.889 9 0 1997 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.080 None 0.875 8 0 1996 2019
Entrez Id: 25902
Gene Symbol: MTHFD1L
MTHFD1L 		Q6UB35 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like Enzyme 41 0.674 0.538 1.9E-12 0.080 None 1.000 8 4 1998 2020
Entrez Id: 57822
Gene Symbol: GRHL3
GRHL3 		Q8TE85 grainyhead like transcription factor 3 Transcription factor 106 0.572 0.692 0.99 0.370 None 1.000 8 0 1983 2019
Entrez Id: 2346
Gene Symbol: FOLH1
FOLH1 		Q04609 folate hydrolase 1 Enzyme 311 0.453 0.885 6.2E-09 0.060 None 1.000 6 7 2003 2018
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA 		P16234 platelet derived growth factor receptor alpha Kinase 452 0.415 0.808 1.00 0.060 None 1.000 6 0 1998 2008
Entrez Id: 2350
Gene Symbol: FOLR2
FOLR2 		P14207 folate receptor beta 105 0.559 0.654 5.5E-06 0.340 None 1.000 5 2 1998 2019
Entrez Id: 6948
Gene Symbol: TCN2
TCN2 		P20062 transcobalamin 2 104 0.578 0.615 1.0E-06 0.050 None 1.000 5 1 1986 2019
Entrez Id: 7546
Gene Symbol: ZIC2
ZIC2 		O95409 Zic family member 2 Transcription factor 125 0.556 0.769 0.97 0.340 None 0.800 5 1 2002 2012
Entrez Id: 27443
Gene Symbol: CECR2
CECR2 		Q9BXF3 CECR2 histone acetyl-lysine reader Epigenetic regulator 15 0.743 0.385 1.00 0.340 None 1.000 5 0 2005 2017